感染症学雑誌
Online ISSN : 1884-569X
Print ISSN : 0387-5911
ISSN-L : 0387-5911
82 巻, 2 号
選択された号の論文の7件中1~7を表示しています
  • 行政機関感染症対策担当者を対象とした質的調査
    堀口 逸子, 柏木 知子, 丸井 英二
    2008 年 82 巻 2 号 p. 67-72
    発行日: 2008/03/20
    公開日: 2011/02/07
    ジャーナル フリー
    目的: 一般住民への普及啓発として, 優先的にされるべき感染症は何であるのか明らかにすることを目的とした.
    対象と方法: 感染症予防対策に従事している行政機関に勤務する医師・獣医師25名に対してデルファイ法によって調査を行った.
    結果: 「疫学的及び臨床的特徴」「住民や医療従事者など関係者の知識の程度や意識行動」「社会的状況と対処」を選出理由として, 24疾患が挙がった.上位より, 結核, インフルエンザ, HIV/AIDS, 腸管出血性大腸菌感染症 (O157), 性器クラミジア感染症で, 上位10位以内に, 動物由来感染症が3疾患入った.
    考察: 感染症全体から普及啓発の必要性に関してそれぞれの疾患の優先順位を明らかにした研究は見られなかった.今回選出された疾患について, 選出理由を裏付ける調査・研究は散見されたが, 今回の研究結果を一般化するには十分とは言えない. また, 選出された上位疾患については, これまでも普及啓発されていると考えられるものがほとんどであった. このことは, これまでの普及啓発の質が問われることを意味している. 今後, さらに効果的な普及啓発について研究を重ねなければならない.今回の調査は優先的に普及啓発すべき感染症を選択する際の根拠の一部分となり得ると考えられる.
  • 萩原 恵里, 関根 朗雅, 佐藤 友英, 馬場 智尚, 篠原 岳, 遠藤 高広, 十河 容子, 西平 隆一, 小松 茂, 松本 裕, 小倉 ...
    2008 年 82 巻 2 号 p. 73-76
    発行日: 2008/03/20
    公開日: 2011/02/07
    ジャーナル フリー
    A 39-year-old man with dyspnea was revealed to have severe pneumothorax and received partial resection of the left upper lobe after unsuccessful drainage. Necrotizing epitheloid granuloma was found in the resected lung and Mycobacterium fortuitum was detected from the lesion. Chemotherapy with levofloxacin and clarithromycin was started one year after surgery because of the newly found nodular shadow near the lesion. The case experienced pyothorax due to pulmonary tuberculosis three years before and Mycobacterium avium pleuritis one year before this episode. Three-time mycobacterial pleural infection in three years seems to be uncommon. Furthermore this is the first report of pneumothorax associated with pulmonary Mycobacterium fortuitum infection.
  • 本邦2例目の死亡例
    和田 桂代子, 栄枝 弘司, 青野 礼, 千屋 誠造
    2008 年 82 巻 2 号 p. 77-81
    発行日: 2008/03/20
    公開日: 2011/02/07
    ジャーナル フリー
    A 77 year-old woman who have no past history, was admitted in a local hospital in Muroto City, Kochi, Japan, after several days of fever and severe general fatigue and generalized skin erythema. She was suspected to haveJapanease spotted fever, which was a local pandemic disease. She was treated with minocycline immediately. The next day, she had consciousness disturbance and low blood pressure. Laboratory findings indicated disseminated intravascular coagulation (DIC) and multiple organ failure. She was referred to our hospital. An eschar was identified in the back of lt. femur. Treatment included minocycline, ciprofloxain, gabexate mesilate, methylprednisolone, hemodialysis and mechanical ventilation. In spite of the avobe treatment, she died 3 days after admission of the local hospital. Though the serological test showed no positive antibody titer against Rickettsia japonica, Rickettsia japonica was isoleted from blood culture, to confirmJapanease spotted fever.Japanease spotted fever is generaly a curative disease with early diagnosis and minocycline. In this case, the patient died 3 days after proper diagnosis and treatment was started. We reported the second fatal Japanease spotted fever case in japan.
  • 古西 満, 米川 真輔, 中川 智代, 宇野 健司, 笠原 敬, 善本 英一郎, 前田 光一, 三笠 桂一
    2008 年 82 巻 2 号 p. 82-85
    発行日: 2008/03/20
    公開日: 2011/02/07
    ジャーナル フリー
    A 69-year-old man treated with corticosteroids and immunosuppressive agents for acutely exacerbated interstitial pneumonia was found to have an ingrown nail in the left big toe and that suppurated despite treatment by dermatologists. Culture of the pus expressed from the toe yielded Scedosporium apiospermum. The patient suffered liver dysfunction a few days later when treated with intravenous voriconazole (VRCZ), which was discontinued due to the high plasma VRCZ concentration. Discrete erythema and subcutaneous nodules developed in left leg 2 or 3 weeks later. Ultrasonography showed tubular structures with substantial echoes that were not connected to veins in the subcutaneous tissue of the left leg. These findings suggested a nodular lymphangitic pattern of spreading of S. apiospermum soft tissue infection. Oral VRCZ at 100 mg/day was started, and increased to 200mg/day after the plasma VRCZ concentration was measured. VRCZ was stopped after about 2 months, by which time the man had fully recovered.
    Because VRCZ-induced liver dysfunction was reported significantly associated with plasma level, we treated this case safely by administering VRCZ while measuring the plasma concentration.
  • 真柴 晃一, 小島 武士, 大塚 毅, 草場 公宏
    2008 年 82 巻 2 号 p. 86-89
    発行日: 2008/03/20
    公開日: 2011/02/07
    ジャーナル フリー
    We report a case ofYersinia pseudotuberculosis (Y. pseudotuberculosis) septicemia in a healthy 22-year-old woman with clinical manifestations including high fever and general fatigue. The patient's ferer sudden elevation of her fever, and, liver damage and elevated inflammatory markers were indicated. General fatigue and appetite loss were noted on hospitalization. Exanthema was recognized, and all oral medications, including antibiotics, was stopped. The fever continued and high inflammatory parameters developed. After chemotherapy with imipenem, subjective symptoms ameliorated. Membranous desquamation without itching appeared between the fingers of both hands but improved naturally.
    Y. psuedotuberculosissepticemia was diagnosed asY. psuedotuberculosisisolated from blood and elevated serum antibody titer againstY. psuedotuberculosis4b detected at 1: 160.
  • 和泉 賢一, 詫間 隆博, 岡田 貴典, 西山 政孝, 横田 英介
    2008 年 82 巻 2 号 p. 90-93
    発行日: 2008/03/20
    公開日: 2011/02/07
    ジャーナル フリー
    We report a rare case of multiple vertebral osteomyelitis due to Streptococcus pneumoniae.
    A 73 year-old man admitted for back pain and a low-grade fever was found in laboratory studies to have severe leukocytosis and increased C-reactive protein, but neither computed tomography (CT) nor vertebral magnetic resonance imaging (MRI) clarified the cause of infection in the painful hip lesion, and paralysis developed. in the left leg MRI eventually indicated a vertebral abscess involving multiple lesions at C4-7 and L4-5.
    We had started antibiotics before blood culture clarified Streptococcus pneumoniae, and antibiotics acted more effectively thereafter. The clinical course was good, little paralysis remained.
  • 2008 年 82 巻 2 号 p. 155
    発行日: 2008年
    公開日: 2011/02/07
    ジャーナル フリー
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