Kansenshogaku Zasshi
Online ISSN : 1884-569X
Print ISSN : 0387-5911
ISSN-L : 0387-5911
Volume 84, Issue 5
Displaying 1-7 of 7 articles from this issue
ORIGINAL ARTICLES
  • Eriko KASUGA, Takehisa MATSUMOTO, Shinichiro KANAI, Kozue OANA, Takayu ...
    2010 Volume 84 Issue 5 Pages 469-574
    Published: September 20, 2010
    Released on J-STAGE: August 18, 2017
    JOURNAL FREE ACCESS
    Carbapenemases including Klebsiella pneumoniae carbapenemases (KPC) are widespread among clinical isolates in the family Enterobacteriaceae. In 2008, we isolated 4 IMP-1 metallo-β-lactamase (MBL) producers of this family having transferable carbapenem-resistance markers. When examined with MicroScan NegCombo Panels, all 4 showed imipenem-MIC of either <1μg/mL or 2μg/mL, although they were highly resistant to ceftazidime (MIC : >16μg/mL). When isolates were examined by Sensi-Disc, however, discrepancies were seen in susceptibility testing results against carbapenems, i.e., some strains were susceptible to imipenem but resistant to meropenem. MBL productivity of isolates could be ensured by both sodium mercaptoacetic acid (SMA) and modified Hodge testing. Noted that atypical carbapenemase-producers may be overlooked in routine clinical microbiology laboratory testing, and both SMA disks and modified Hodge tests proved appropriate for accurately detecting such carbapenemase-producers.
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  • Masato KAWAMURA, Taro KAMIGAKI, Nao NUKIWA, Akiko HASHIMOTO, Raita TAM ...
    2010 Volume 84 Issue 5 Pages 575-582
    Published: September 20, 2010
    Released on J-STAGE: August 18, 2017
    JOURNAL FREE ACCESS
    Many influenza-like illness (ILI) outpatients visit healthcare facilities such as internal medicine and pediatric clinics every year. In Japan, however, ILI is reported only by sentinel healthcare facilities. We studied the number of ILI subjects visiting sentinel and non-sentinel healthcare facilities during the 2008-09 season in Saku, Nagano prefecture, obtaining the numbers of cases from sentinel and non-sentinel facilities. Most ILI subjects visited internal and pediatric facilities, and some visited otorhinolaryngological clinics not included as sentinel sites. We also estimated the total number of influenza cases based on data from sentinel facilities and total surveyed facilities, including non-sentinel. We divided facilities into hospitals with pediatrics, pediatric clinics, internal medicine and pediatric clinics, hospitals and clinics with internal medicine but no pediatrics, and otorhinolaryngological clinics. Estimated sentinel-site ILI cases was 2,862, including 1,020 for hospitals with pediatrics and 1,674 for clinics with internal medicine and pediatrics. The estimated number of ILI cases from total facilities surveyed was significantly lower, at 503 for hospitals with pediatrics,and 741 for clinics with internal medicine and pediatrics. Estimated ILI cases from categories not including sentinel sites were 967 for hospitals and clinics with internal medicine but no pediatrics, and 71 for otorhinolaryngological clinics. The estimated number of total ILI cases differed by 18.5%, depending on facility categories. This indicates that more detailed analysis is needed to accurately estimate ILI cases.
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  • Myonsun YOH, Junko MATSUYAMA, Akiko SHIME, Kana OKAYAMA, Rei SAKAMOTO, ...
    2010 Volume 84 Issue 5 Pages 583-587
    Published: September 20, 2010
    Released on J-STAGE: August 18, 2017
    JOURNAL FREE ACCESS
    Contaminated hospital linen has caused some cases of Bacillus cereus bacteremia in Japan. We analyzed the disinfection efficacy of industrial washing of hospital towels and sheets by counting the number of B. cereus on linen before and after washing. That before washing averaged 7.6 cells/cm2 on unwashed sheets,decreasing to 1.2 cells/cm2 after washing. That on unwashed towels, however, averaged 106 cells/cm2 before washing and 1,096cells/cm2 after washing, which was very high and suggested the possibility of causingnosocomial infection.
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CASE REPORTS
  • Takahiro FUJITA, Yoshiaki GU, Naoki KISHIDA, Keiji OKINAKA, Norio OHMA ...
    2010 Volume 84 Issue 5 Pages 588-591
    Published: September 20, 2010
    Released on J-STAGE: August 18, 2017
    JOURNAL FREE ACCESS
    Pseudomonas aeruginosa, the leading nosocomial pneumonia pathogen in immunocompromised patients,has Recently become typically presented as slowly progressive ventilator-associated pneumonia. We report two cases of bacteremic pneumonia due to Pseudomonas aeruginosa in non-neutropenic solid-organ cancer. Both subjects had sudden sepsis or septic shock but few respiratory symptoms. Chest radiography showed a diffuse unilateral decrease in permeability, becoming necrotizing pneumonia and lung abscess in 7- 10 days. Conventional literature describe fulminant pseudomonas bacteremic pneumonia in non-neutropenic immunocompromised hosts as the initial presentation with septic shock and interstitial lung opacity, leading lung abscess.
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  • Yumiko HOSAKA, Takuma KIMURA, Ryo SUZUKI, Tonghyo CHONG, Michi SHOJI, ...
    2010 Volume 84 Issue 5 Pages 592-596
    Published: September 20, 2010
    Released on J-STAGE: August 18, 2017
    JOURNAL FREE ACCESS
    A 64-year-old man with prostate cancer and bone metastasis admitted for nausea, left abdominal pain showed no abnormal, and fever, abdominal ultrasound or chest X-ray findings. Despite antibiotics, left abdominal pain persisted for several days. Abdominal computed tomography (CT), showed splenic infarction. Transesophageal echocardiography suggested infectious endocarditis (IE) as a possible infarction cause, and roth spots were found on the retina. Gemella morbillorum was detected from blood culture. IE commonly causes Fever of Unknown Origin found by infarction. G. morbillorum, an anaerobic grampositive, viridans group streptococci, is indigenous to the oropharynx, upper respiratory, urogenital, and gastrointestinal tracts, and is thought to have weak toxity and pathogenicity in the body.
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  • Naoki KISHIDA, Keiji OKINAKA, Takahiro FUJITA, Yoshiaki GU, Norio OHMA ...
    2010 Volume 84 Issue 5 Pages 597-601
    Published: September 20, 2010
    Released on J-STAGE: August 18, 2017
    JOURNAL FREE ACCESS
    Cryptococcal lung disease is usually diagnosed by chest X-ray abnormalities. Although no treatment exists for asymptomatically immunocompetent patients, a case with central nervous system (CNS) involvement as cryptococcus dissemination had a new chest X-ray abnormality during marked eosinophilia diagnosed as pulmonary cryptococcosis by lung biopsy. Eosinophilia may thus be associated with pulmonary cryptococcosis. We had seen reports of disseminated cryptococcosis with eosinophilia, so we conducted lumbar puncture and blood culture, but found no disseminated lesion or CNS involvement. Eosinophilia association with disseminated cryptococcosis has been reported, but not pulmonary cryptococcosis with solitary localized lung lesion with marked eosinophilia, making our case the first, in so far as we know reported of pulmonary cryptococcosis with a solitary localized lung leision with marked eosinophilia.
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  • Yusuke AINODA, Yuji HIRAI, Takayo SHOJI, Kyoichi TOTSUKA
    2010 Volume 84 Issue 5 Pages 602-605
    Published: September 20, 2010
    Released on J-STAGE: August 18, 2017
    JOURNAL FREE ACCESS
    Non-Hodgkinʼs lymphoma, a hematolymphoid malignancy, puts subjects at risk for complete infection. A 65-year-old man with non-Hodgkinʼs lymphoma Stage IV had undergone 5 R-CHOP courses in May 2008. Six days later, he was hospitalized for a high fever for which he was initially administered cefepime. When blood culture was positive for Listeria monocytogenes, he was administered ampicillin. His medical interview indicated that he had gone hunting and dressed wild animal meat at his mountain retreat, where he was exposed to wild animals and their excreta following R-CHOP course 5. CSF was not checked because his general condition was good. On hospital day 2, his fever dropped, and he was discharged following two weeks of ampicillin administration. Listeriosis cases reported in Japan number far fewer than in the United States, France or Germany. From January 1983 to February 2009, 153 cases were reported in Japan, 12 of whom were cancer patients. Despite the high incidence of meningitis with listeriosis, 7 of the 12 were not examined for CSF-an examination necessary in listeriosis, however well the subject appears.
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