Kanzo
Online ISSN : 1881-3593
Print ISSN : 0451-4203
ISSN-L : 0451-4203
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Volume 47, Issue 11
Displaying 1-6 of 6 articles from this issue
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Review Article
Editorial
Case Reports
  • Hyperplastic nodules of the liver in a patient with alcoholic liver cirrhosis: follow-up for six years
    Yuko Masaki, Takeaki Satoh, Makoto Okada, Jiro Watanabe, Haruo Kuwano, ...
    2006 Volume 47 Issue 11 Pages 503-510
    Published: 2006
    Released on J-STAGE: February 21, 2007
    DOIhttps://doi.org/10.2957/kanzo.47.503
    JOURNAL FREE ACCESS
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    A 38-year-old female was diagnosed as alcoholic liver cirrhosis in 1996. In 1999, ultrasound (US) examination of her liver revealed multiple hypoechoic nodules, 10-20 mm in diameter. US-guided biopsy of S8 nodule was performed, and the lesion was histologically diagnosed as hyperplastic nodule. Follow-up biopsy in 2002 gave the same pathological diagnosis as before, although the lesion showed a change of contrast-enhanced appearance in computed tomography (CT). This nodule gradually decreased in size and finally disappeared in 2005. S4 nodule, which was newly visualized with diameter of 5 mm in 2000, gradually increased in size. In 2004, the lesion reached 20 mm in diameter, and was diagnosed as hyperplastic nodule by targeted biopsy. A year later, the lesion showed an increase in size up to 30 mm in diameter and a distinctive change of enhanced configurations in CT. Follow-up biopsy revealed similar histopathological findings to those of the previous one.
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  • Metastasis of sarcomatous hepatocellular carcinoma to myocardium: an autopsy case
    Tadashi Doi, Shyouhei Kikuchi, Toshinori Okuda, Yasuhiro Sato, Hidetos ...
    2006 Volume 47 Issue 11 Pages 511-515
    Published: 2006
    Released on J-STAGE: February 21, 2007
    DOIhttps://doi.org/10.2957/kanzo.47.511
    JOURNAL FREE ACCESS
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    We report an unusual case of metastasis of sarcomatous HCC to the heart. The patient was a 74-year-old man who was found to have HCC in July 2002. He had undergone transcatheter arterial embolization 3 times from July 2002 to June 2003. In February 2004, he began to complain of general fatigue and backache. Abdominal CT revealed a hypovascular liver tumor measuring 6cm in diameter in segment IV of the liver with an accumulation of lipiodol in the center of the tumor. Sixteen days after admission, he died suddenly of unidentified cause and an autopsy was performed. Several nodules were scattered through segement IV, II and III. Hepatic tumor involving segment IV with massive invasion into the diaphragm was observed. The sarcomatoid cells had metastasized to the lung, bone, bilateral adrenal glands and myocardium. Histologically, the hepatic tumor and all of metastatic lesions consisted of spindle-shaped sarcomatoid cells. Immunohistochemical study showed that the sarcomatoid cells were positively stained for cytokeratin and vimentin.
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Rapid Communication
  • Timing of withdrawal of lamivudine treatment for HBeAg-negative chronic hepatitis B patients
    Takatoshi Kitada, Noriyoshi Kuzushita, Eiji Miyoshi, Shinji Tamura, No ...
    2006 Volume 47 Issue 11 Pages 516-517
    Published: 2006
    Released on J-STAGE: February 21, 2007
    DOIhttps://doi.org/10.2957/kanzo.47.516
    JOURNAL FREE ACCESS
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    We studied the timing of withdrawal of lamivudine administration for HBe Ag-negative chronic patients. The amount of serum HBV DNA was measured using the Amplicor HBV monitor (AM) and the Real-time Detection direct (RTD-direct). All values became less than 2.6 log copies/ml according to the AM method after administration. Five of 16 patients were found to have no HBV according to the RTD-direct (less than 1.0 log copies/ml). Thus, withdrawal of administration was attempted for these five patients. After the withdrawal, the viral load and ALT levels had increased in all patients. These results showed the difficulty of withdrawing lamivudine administration from HBe Ag-negative chronic patients, even though they have very low viral load in serum by the treatment.
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Special Article
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