The Journal of the Kyushu Dental Society
Online ISSN : 1880-8719
Print ISSN : 0368-6833
ISSN-L : 0368-6833
Volume 61, Issue 2.3
Displaying 1-4 of 4 articles from this issue
Oliginal Articles
  • Min Zhang, Hiroshi Fukuyama, Kou Matsuo, Yoshihiro Yamashita, Soichi H ...
    Article type: Original Article
    2007 Volume 61 Issue 2.3 Pages 55-66
    Published: 2007
    Released on J-STAGE: September 16, 2008
    JOURNAL FREE ACCESS
    The revised histopathological classification of odontogenic tumours by the World Health Organization (WHO) was published in 2005 in "Pathology and Genetics of the Head and Neck Tumours". This study sought to determine the relative frequency of odontogenic tumours in the Japanese population and to compare these data with previous classifications of odontogenic tumours.
    289 patients with odontogenic tumours diagnosed at the Department of Oral Pathology in Kyushu Dental College, Japan during a 20-year period from 1985 to 2004 were reviewed and reclassified according to the revised histopathological classification of odontogenic tumours by WHO published in 2005. Clinical data, including frequency, age, gender, and anatomical location, were also analyzed and collected.
    Odontogenic tumours accounted for 4.1% of all the oral and maxillofacial lesions (n=289).Of these, 289 patients (99.31%) had benign tumours and 2 (0.69%) had malignant tumours. The most frequent of the benign tumours were keratocystic odontogenic tumours (n=86), followed by ameloblastomas (n=81) and odontomas (n=79).These tumours constituted 84.43% of the all the odontogenic tumours. The mean age for benign odontogenic tumours was 32.36 ±19.83 years and for malignant tumours was 30 years, with the majority 189 (65.40%) of odontogenic tumours occurring in the second and the third molar region of the mandible, especially the posterior region 139 (48.10%). The male:female ratio for the all odontogenic tumours was 1:0.91.
    Conclusions:Keratocystic odontogenic tumours therefore tend to show a higher frequency of occurrence among odontogenic tumours than ameloblastoma, according to this new classification.
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  • Kazumi Sakamoto, Kou Matsuo, Tomotaka Hayashi, Mitsuhiro Yoshida, Min ...
    Article type: Original Article
    2007 Volume 61 Issue 2.3 Pages 67-76
    Published: 2007
    Released on J-STAGE: September 16, 2008
    JOURNAL FREE ACCESS
    Thymosinβ4 (TB4), a 43 amino acid (a.a.) peptide, is regarded as the main globular-actin (G-actin) sequestering peptide which binds to G-actin and prevents polymerization into actin filament. Recent studies have revealed that TB4 is a multifunctional peptide involved in cell migration, angiogenesis, wound healing, inflammation, morphogenesis and tumor metastasis. However, there are few reports associated with dental research, except for our previous reports suggesting the important role of TB4 in tooth germ development. In this study, we investigated the effects of TB4 on wound healing after tooth extraction, using a 20 a.a. synthetic peptide which includes the nine a.a. G-actin binding motif and the seven a.a essential site for angiogenic activity. After extraction of a rat mandibular first molar tooth, the synthetic peptide was injected intraperitoneously into each rat at the time of extraction and every day thereafter for four days. Controls for the treatment received identical amounts of phosphate buffered saline in the same manner. Histological sections were processed from decalcified mandibles of Day2, Day3 and Day4 cases. Histochemical and immunohistochemical stainings were also performed as needed. Total RNAs from granulation tissues in the sockets were isolated, and semi-quantitative RT-PCR for matrix metalloproteinase-2 (MMP-2) and vascular endothelial growth factor (VEFG) genes was performed. MMP-2 was only amplifed in TB4-treated samples. Though VEGF was detected in both TB4-treated and control samples, the expression level in TB4-treated cases was lower than with controls. Histological examination showed that the synthetic peptide accelerates the process of wound healing after tooth extraction such as absorption of blood clots, formation of granulation tissue, reepithelialization and new bone formation. These results demonstrate the usefulness of TB4 in dental clinical application.
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  • Keiko Nakamura, Shin-ichi Masumi, Shunsuke Andoh, Toshihiro Takeuchi, ...
    Article type: Original Article
    2007 Volume 61 Issue 2.3 Pages 77-81
    Published: 2007
    Released on J-STAGE: September 16, 2008
    JOURNAL FREE ACCESS
    The mandibular torus is a bony protuberance and its contributory causes include heredity, masticatory pressure and/or parafunction. However, no obvious single cause is known.
    In this study, we evaluated the relationships between mandibular torus and occlusal force, occlusal contact area and parafunction by using a dental prescaleTM and questionnaire. All subjects were patients who visited Kyushu Dental College Hospital for dental treatment.
    The relationships between the presence or absence of mandibular torus and maximum occlusal force showed statistically significant differences. Also the relationships between the presence or absence of mandibular torus and occlusal contact area showed statistically significant differences. Moreover, the relationships between the presence or absence of mandibular torus and parafunction, especially clenching and preference for hard food showed statistically significant differences based on results of the questionnaire. However, there was no relationship between mandibular torus and grinding, muscle pain, or stress, based on the results of questionnaire.
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  • Part 1:Coating Methods for a Titanium Dioxide Coating Solution on Acrylic Resin Plates
    Eri Makihara, Shin-ichi Masumi, Masahiro Arita, Toshihiro Takeuchi, To ...
    Article type: Original Article
    2007 Volume 61 Issue 2.3 Pages 82-86
    Published: 2007
    Released on J-STAGE: September 16, 2008
    JOURNAL FREE ACCESS
    Denture plaque control is very important for elderly patients with removable dentures to keep their oral cavity healthy. We thought that a titanium dioxide solution could remove denture plaque and investigated coating methods for this solution on acrylic resin plate in this first report. Two types of acrylic resin plates polished with different stage (paper-corn and lathe) were made. Two types of solutions (an original solution and a solution with a surfactant material) were painted on the surface of these resin plates. Although the combination a resin plate with lathe polishing and an original solution made an uniform coating impossible, the combination a resin plate with paper-corn polishing and an original solution did allow an uniform coating. On the other hand, the combination a resin plate with lathe polishing and an original solution with surfactant material allowed a more uniform and smooth coating than the combination a resin plate with paper-corn polishing and an original solution with surfactant material. We found that the best coating method was the combination a resin plate with lathe polishing and an original solution with surfactant material.
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