All issues
Volume 64 (2010 - 201･･･
- Issue 6 Pages 201-
- Issue 5 Pages 169-
- Issue 4 Pages 93-
- Issue 3 Pages 59-
- Issue 2 Pages 15-
- Issue 1 Pages 1-
Volume 64, Issue 3
Displaying 1-4 of 4 articles from this issue
- |<
- <
- 1
- >
- >|
-
Hisako Hikiji2010 Volume 64 Issue 3 Pages 59-65
Published: October 25, 2010
Released on J-STAGE: September 09, 2024
JOURNAL FREE ACCESSBiomembranes function as barriers and serve as stores for precursors of lipid mediators. Phospholipases generate lipid mediators such as prostaglandins, leukotrienes, and lysophospholipids. The production of a variety of lipid mediators is enhanced in bone resorptive disorders such as osteoporosis, rheumatoid arthritis, osteoarthritis, and periodontitis. Many studies have examined the physiological and pathological effects of prostanoids, especially PGE2, on bone. PGE2 is one of the most important local regulators of bone metabolism. In vitro studies have demonstrated that PGE, promotes osteoclast formation, thus leading to bone resorption. However, PGE2 also promotes bone formation by stimulating osteoblast proliferation and differentiation. These contrasting PGE2-mediated activities make it difficult to understand precisely its role during bone remodeling. Other lipid mediators including leukotrienes and lysophospholipids also play an important role in bone metabolism. In vivo studies using receptor gene-deficient mice have shown that these lipid mediators enhance osteoclast functions, thus leading to bone resorption. Here, we provide an overview of and an update regarding recent developments in the study of lipid mediators and their role in bone metabolism.View full abstractDownload PDF (809K) -
Chiaki Kitamura, Takanobu Nishino, Junya Yano, Masato Nagayoshi, Ayako ...2010 Volume 64 Issue 3 Pages 66-73
Published: October 25, 2010
Released on J-STAGE: September 09, 2024
JOURNAL FREE ACCESSWith the establishment of dental prophylaxis, rising standards of oral care, and the advent of an aging society, higher accuracy of dentists'skils in diagnosis and treatment becomes further required. At the same time, with the development of high precision devices for diagnosis and treatment, exteriorization of intractable and chronic pain, and increase in expectations for regenerative therapy, the direction of research in conservative dentistry has been changing. Here, we would like to introduce the current status of conservative dentistry, as well as that of our research.View full abstractDownload PDF (1969K) -
Eijiro Jimi, Shizu Hirata, Hidefumi Fukushima2010 Volume 64 Issue 3 Pages 74-83
Published: October 25, 2010
Released on J-STAGE: September 09, 2024
JOURNAL FREE ACCESSIn case of implantation involving large bone defects, the gold standard for reconstruction of these defects is the use of autogeneous bone grafts. However, the use of autogeneous bone is limited by concerns for donor site morbidity and its finite supply. Recently, regenerative medicine has been developing in various areas. Regenerative medicine is the process of creating living, functional tissues to repair or replace tissue or organ function lost due to age, disease, damage, or congenital defects. Tissues and organs are prepared in the laboratory and then safely implanted into the defect. Importantly, regenerative medicine has the potential to solve the problem of the shortage of organs available for donation compared to the number of patients who require lifesaving organ transplantation, as well as to solve the problem of organ transplant rejection, since the organ's cells will match those of the patknt. In this review, we summarize the basic concepts of regenerative medicine, such as stem cells, scaffolds, and grow出factors. We also introduce recent advances in tooth and bone regeneration in the oral area using cell-based techniques.View full abstractDownload PDF (1276K) -
Ikuya Miyamoto, Kenkou Tanaka, Kensuke Yamauchi, Noriaki Yamamoto, Yos ...2010 Volume 64 Issue 3 Pages 84-88
Published: October 25, 2010
Released on J-STAGE: September 09, 2024
JOURNAL FREE ACCESSThis case report describes a case of juvenile masticatory muscle tendon-aponeurosis hyperplasia. A 15 year-old boy had been complaining of a vague feeling of discomfort when opening his mouth since he was in the uppergrades of elementary school, and he was referred to our hospital. Three-dimensional computed tomography revealed that bilateral hyperplasia of the coronoid process of the mandible and interference of the coronoid process of the mandible and zygomatic arch were detected. Under general anesthesia, the bilateral coronoid processes were surgically resected and a bilateral-angle splitting osteotomy was performed. After 20 months follow-up, symptoms completely disappeared and sufficient range of jaw-opening was retained.View full abstractDownload PDF (1115K)
- |<
- <
- 1
- >
- >|