Kekkaku(Tuberculosis)
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
Volume 29, Issue 11
Displaying 1-8 of 8 articles from this issue
  • TOYOHO MUROHASHI, TATSUICHIRO HASHIMOTO, HIROSHI TAKAHASHI
    1954 Volume 29 Issue 11 Pages 423-426
    Published: November 15, 1954
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    Studies were made on the relationship between the viable units of the dried BCG vaccine of mass production (products from the year 1949 to 1951) and the course of tuberculin allergy produced by it in pupils received the primary inoculation.
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  • I. STUDIES ON THE CELL GROWTH, THE UTILIZATION AND BIOSYNTHESIS OF AMINOACIDS, AND THE PH OF CULTURE FILTRA TES
    TOMIO KATAYAMA, SHINICHI TANAKA
    1954 Volume 29 Issue 11 Pages 427-432
    Published: November 15, 1954
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    In the presence of various aminoacids as nitrogen source in Sauton culture, the cell growth rate of tubercle bacillus (avian Jucho strain) and its aminoacids utilization and their biosynthesis were investigated by paper chromatography.
    1. In these experiments, no difference between streptomycin resistant strain (R-strain) and its sensitive one (S-strain), were found except in asparagine Sauton culture. In asparagine Sauton culture, S-strain exceeds R-strain in growth rate, and it may be said that the asparaginase activity in R-strain is a little higher than in S-strain.
    2. The tubercle bacillus markedly utilizes L-asparagine, L-alanine, L-histidine, and L-arginine, and moderately L-aspartic acid, D-alanine, L- and D-glutamic acid, and glycine. DL-serine and DL-phenylalanine were little effective as its nitrogen source. L-lysine and DL-methionine were not utilized at all.
    3. Concerning streoisomer of these aminoacids, L-form was more effective than D-form.
    4. The aminoacids biosynthesis in their culture filtrates such as aspartic acid, glutamic acid, alanine, serine, and valine was observed by paperchromatography.
    5. The pH of their culture filtrate inclines alkaline with their culture ages. When L-arginine and L-histidine were used as nitrogen source, the pH of their culture filtrate was lower then in other cases.
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  • II. ON THE FLUCTUATION OF BODY-WEIGHT DUE TO THORACOPLASTY
    HISATAKA UGAI
    1954 Volume 29 Issue 11 Pages 433-436
    Published: November 15, 1954
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    As reported in Part I on the artificial pneumothorax cases, observations were made on the fluctuation in the body weight of 106 pulmonary tuberculosis patients who had undergone thoracoplasty with desired results.
    More than a half of the patients observed lost weight by the end of six months after treatment. Those who had more ribs taken away, viz, those who had larger collapse in their lungs were more likely to lose their weight than the others. Neither the condition and the dimensions of the lesions of lungs before the treatment, whether or not chemotherapy was applied, nor whether or not blood transfusion was made after operation, had anything to do with the fluctuation in their body weight.
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  • KEN YANAGISAWA, OYOHO MUROHASHI, NOZOMU ASAMI, MASAHARU HOSOI, KOJI TS ...
    1954 Volume 29 Issue 11 Pages 437-441
    Published: November 15, 1954
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    Potency of old tuberculin together with purified tuberculin (PT) which have been in use in japan was compared with those of Denmark, Sweeden, Norway, England and of America. Comparisons were done on both animal and human following the method described under the potency test of the minimum requirements for the diluted old tuberculin to be used in Mantoux test.
    The findings of the comparisons are shown in the tables from which it has been concluded as follows:
    1. The potency of Japanese OT was found to be equivalent to those used in Denmark, Norway, England and America, however, the one used in Sweeden was found to be slightly lower.
    2. The potency of our UT in a dilution of 1: 2, 000 (0.05 mg/0.1 ml) was found to be equivalent to the 5 TU (0.1 γ/0.1 ml) of PT used in Denmark.
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  • YUTAKA SHIRAI
    1954 Volume 29 Issue 11 Pages 442-444
    Published: November 15, 1954
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    Investigations were made, this time, on the decomposition of 1-tyrosine by various tubercle bacilli excepting the avian type and non-pathogenic ones.
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  • MASAO SUGIYAMA, SHINICHI TANAKA
    1954 Volume 29 Issue 11 Pages 445-455
    Published: November 15, 1954
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    Biochemical studies of the problems on the appearance of streptomycin resistant organisms in tubercle bacilli have been undertaken from the genetic point of view.
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  • HIROSHI OKAMOTO
    1954 Volume 29 Issue 11 Pages 456-457
    Published: November 15, 1954
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    In 18 cases of the inpatients at the Fukuoka National Sanatorium from January to June 1954, pleural punctures were made for the comparisons of 02 and CO2 contents between the respiratory air and that obtained by pleural puncture. Following are the results obtairied thereof.
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  • II. STUDIES ON THE PHARMACO-DYNAMIC FUNCTIONS OF PARA-AMINOSALICYLIC ACID AND ISONICOTINIC ACID HYDRAZIDE
    MASAYASU YAMASAKI, SYUJI DAIMON
    1954 Volume 29 Issue 11 Pages 458-460
    Published: November 15, 1954
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    Our previous study demonstrated the effect of streptomycin (STM) on the autonomic nervous functions and we ascertained that STM promoted the function of the parasympathetic nervous system.
    In this report, the experiments on the action of para-aminosalicylic acid (PAS) and isonicotinic acid hydrazid (INAH) on the autonomic nervous functions were performed as in the case of STM (1st report).
    The results of these experiments show that PAS and INAH give little effect on the intestinal tracts of guinea pigs and on the blood pressure of rabbits, and that these drugs neither promote the action of acetylcholin, nor inhibit the action of epinephrine. Furthermore, PAS and INAH have no inhibitory effect upon cholinesterase in the blood serum. But when rabbits are administered with a large dose of INAH, it produces a convulsion. An excessive dose of INAH, therefore, may stimulate the sympathetic nervous system. From these facts, it is conceivable that PAS and INAH, unlike STM, have little effect directly on the autonomic nervous system of the living body.
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