巻号一覧
42 巻, 6 号
選択された号の論文の4件中1～4を表示しています
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亀田 和彦1967 年 42 巻 6 号 p. 197-202
発行日: 1967年
公開日: 2011/05/24
ジャーナル フリーCultivation of tubercle bacilli and drug resistance test were carried out on 500 resected specimens of pulmonary tuberculosis which were treated with chemotherapy before operation during the period from 1962 to 1966 in our sanatorium. The strains were defined as resistant if there was equal growth of tubercle bacilli on culture media containing 10 mcg SM, 1 mcg PAS, or 0.1 mcg INH. A schema useful for treatment was designed from the results of this study with special reference to the clinical course (Fig.5).抄録全体を表示PDF形式でダウンロード (1316K) -
中川 英雄, 砂原 茂一1967 年 42 巻 6 号 p. 203-212
発行日: 1967年
公開日: 2011/05/24
ジャーナル フリーSunahara et al. have reported that t h e frequency distribution curve of the biologically active isoniazid serum levels was trimodal, corresponding to the three patterns of isoniazid metabolism: slow, intermediate and rapid inactivation. They classified the subjects as rapid inactivators if the concentration at 6 hours after the oral dose of 4 mg of isoniazid per kg of body weight was equal to or less than 0.15μg per ml, intermediate if it was between 0. la and 0.8μg per ml, and slow if it was equal to or greater than 0.8μg per ml. But such a classification of isoniazid metabolism obtained by a biological assay method has not yet been confirmed by a chemical assay method. In this study, the investigation on the metabolic patterns in the isoniazid metabolism was undertaken by the chemical assay method of isoniazid which had been devised by Nakagawa, and a few factors participating in the isoniazid metabolism were also studied.抄録全体を表示PDF形式でダウンロード (2013K) -
束村 道雄, 束村 純雄, 板坂 安修1967 年 42 巻 6 号 p. 213-218
発行日: 1967年
公開日: 2011/05/24
ジャーナル フリーBacteriological and biochemical characters of rapidly growing mycobacteria that caused pulmonary disease were studied in comparison with three Mycobacterium runyonii strains and ten Mycobacterium fortuitum strains. Pathogenic rapid growers tested were one strain from patient Yamamoto (Urabe & Kawai, 1957), one strain from patient Sato (Konno et al., 1964) and six strains from patient Yoshida. The third case was found in our hospital and described firstly in this paper. The patient is a forty-year old woman and had a large cavity in her left upper lobe. In spite of the presence of drug resistances to all antituberculous drugs (streptomycin, PAS, isoniazid, kanamycin, ethionamide, cycloserine and ethambutol), the cavity was closed by a six-month-regimen of the chemotherapy with streptomycin, PAS and isoniazid, but leaving a continuous excretion of a small number of acid-fast bacilli other than tubercle bacilli in her sputum.抄録全体を表示PDF形式でダウンロード (1060K) -
束村 道雄, 束村 純雄, 水野 松司1967 年 42 巻 6 号 p. 219-224
発行日: 1967年
公開日: 2011/05/24
ジャーナル フリーIt was shown in the second report of this study (Kekkaku 41: 401, 1966) that the pathogenic scotochromogens isolated in this country represented almost uniform characters and could be considered to form one species. We obtained a number of well documented strains of the group II scotochromogens from the American Type Culture Collection in the courtesy of Dr. E. H. Runyon and Dr. E. F. Lessel and compared them with the pathogenic scotochromogens isolated in Japan.抄録全体を表示PDF形式でダウンロード (1211K)
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