Kekkaku(Tuberculosis)
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
Volume 43, Issue 11
Displaying 1-4 of 4 articles from this issue
  • Hiroshi NAGANO
    1968 Volume 43 Issue 11 Pages 461-472
    Published: 1968
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    Although previous studies on the incidence of unclassified mycobacteria in Japan revealed the rate of 0.2 to 3.5% in healthy persons, 0.5 to 1.3% in patients in tuberculosis sanatorium and 0.6 to 12.5% in factory workers, the incidence of unclassified mycobacteria in patients with non-tuberculous respiratory diseases has not yet been reported in Japan. The purpose of this paper is to isolate unclassified mycobacteria am o ng patients with nontuberculous respiratory diseases and to differentiate unclassified mycobacteria from mycobacterial strains cultured at the laboratory. Unclassified mycobac t eria was isolated and differentiated from the materials in each of the following three groups: The first group consists of sputa taken from 142 cases with nontuberculous respiratory diseases from February 1963 to February 1965, the second group consists of mycobacterial strains which were obtained by mycobacterial culture of sputa and gastric lavage at the laboratory from September 1964 to February 1965, the third group, mycobacterial strains, which showed unusual colony formation and/or resistance to antituberculous drugs(SM, PAS, INH) though previously untreated, from February 1963 to August 1964. As the results of this study, 20 strains of unclassified mycobacteria we r e obtained, the total rate of isolation of unclassified mycobacteria was 1.1%, and it was 4.9% in the first group and 0.4% in the second groud Therefore a high incidence was revealed in the patients with non-tuberculous respiratory diseases. In the second group, 3 s t r ains (5.3%) of unclassified mycobacteria were differentiated from 56 mycobacterial strains. It suggests that the differentiation between unclassified mycobacteria and Mycobacterium tuberculosis is necessary as a routine procedure in the laboratory. The diagnosis of the patients, at the isolation, was as follows: 13 ca s es of pulmonary tuberculosis, 2 cases of pulmonary emphysema, 1 case of chronic bronchitis, 1 case of pulmonary cancer, 1 case of sarcoidosis, 1 case of systemic lupus erythematosus and 1 case of Goodpasture's syndrome. No ca s es with non-tuberculous respiratory diseases fulfilled the diagnostic criteria of unclassified mycobacteriosis by Hibino. According to Runyon's classi f ication, 18 strains were Nonphotochromogens, 1 strain was Scotochromogens and another 1 strain was Rapid growers. The frequency of isolation of unclassified myc o bacteria was only once in 11 cases, twice in 4 cases, 3 times in 3 cases, 5 times in 1 case and 7 times in 1 case.
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  • Toshio OHSATO, Mareichi TOYOHARA, Masakazu AOKI, Hiroshi HATORI
    1968 Volume 43 Issue 11 Pages 473-479
    Published: 1968
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    To clarify the reasons why the infection of INH highly-resistant tubercle bacilli is much less frequent than that of SM highly-resistant tubercle bacilli, the following experiments were carried out. The methods and the results of experiments were summarized as follows: 1. First experiment The propor t ion of INH resistant bacilli in the strains isolated from 9 patients discharging bacilli completely resistant for 5 mcg INH clinically, was examined by using the proportion method, and 2 out of 9 strains did not show full population of resistance for 5 mcg INH.
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  • Tsuneo MATSUYAMA
    1968 Volume 43 Issue 11 Pages 481-488
    Published: 1968
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    Since July 1960 when the aftercare institution was established in Yawata Iron and Steel Works as a rehabilitation center for pulmonary tuberculosis patients after the hospital treatment, the total number of persons entered to the institution amounted to 838 up to the end of 1967. During six months stay in the institution, their prognosis was pretty favorable and the relapse rate was only 2 percent. The restoration of their pulmonary functions and physical abilities has been so remarkable that they are able to work in their former jobs. These results were already reported in the 38th annual meeting of the Japanese Society for Tuberculosis and published in the Bulletin of the Research Institute for Diseases of the Chest of Kyushu University.
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  • 1968 Volume 43 Issue 11 Pages 489-502
    Published: 1968
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
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