巻号一覧
55 巻, 5 号
選択された号の論文の6件中1～6を表示しています
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島尾 忠男1980 年 55 巻 5 号 p. 225-229
発行日: 1980/05/15
公開日: 2011/05/24
ジャーナル フリーA review on tuberculosis prevalence and its control programme in Kanto Region was made based on the routine annual statistics of tuberculosis registry and the results of sampling survey of tubercu losis registry in 1978. The region consists of metropolis Tokyo, 2 municipalities and 8 prefectures. The results are summarized as follows:
1) The prevalence of tuberculosis in the region was, in general, lower than the national average. Tochigi, Ibaragi, Yamanashi and Yokohama were areas in which the prevalence was relatively high within the region.
2) Most of newly registered tuberculosis patients were detected by symptomatic visit to physi cians. The time interval from the appearance of symptoms to the first visit to physicians was slightly longer in the region except Kawasaki than the national average.
3) The rate of bacteriological examination among newly registered patients was 83% in whole Japan, and the rates in Tochigi and Nagano were lower than the national average.
4) No information on the activity of patients within one year was available in 21 % of all regis tered persons in whole Japan, and the rate was higher than this figure in Tochigi, Saitama, Chiba and Ibaragi.
5) The average duration of treatment as well as of registration was longer in Tochigi, Ibaragi and Nagano than those of whole Japan. The use of rifampicin was less in Ibaragi, Tochigi and Chiba. The duration of treatment has to be shortened through the active introduction of intensive regimen of chemotherapy containing isoniazid and rifampicin.
6) The ratio of tuberculosis death to pulmonary cancer death might be used as an index to make the overall evaluation of tuberculosis control programme, as both diseases are highly prevalent among male of higher age, and the reduction of tuberculosis problem could be accelerated through the active implementation of the control programme, while the control of lung cancer is still rather difficult. Tuberculosis death was 44% of pulmonary cancer death, and the ratio in Ibaragi (28), Nagano (30), Gumma and Chiba (33 each), Kawasaki (37) and Yokohama (38) was lower, the ratio. in Yamanashi and Tokyo (43 each), Saitama (44) and Kanagawa (45) was nearly similar, and the ratio in Tochigi (56) was much higher than the national average.抄録全体を表示PDF形式でダウンロード (715K) -
高田 伸介1980 年 55 巻 5 号 p. 231-240
発行日: 1980/05/15
公開日: 2011/05/24
ジャーナル フリーRecently, some pulmonary diseases such as sarcoidosis, Hamman-Rich's syndrome and Good pasture's syndrome are thought to be caused by immunological reactions. As to animal models of these diseases, there are many reports on pulmonary lesions induced by lung antigen.
In this study, allogeneic soluble antigen was injected to mice subcutaneously and the lung tissue was studied by light microscopy and electron microscopy.
Allogeneic soluble lung antigen was shown to be capable of producing pulmonary lesions in mice following subcutaneous injection. The pulmonary lesions were consisted of the followings; a) peribronchial and perivascular plasma cell aggregation; b) numerous macrophage infiltration into the alveolar space; c) swelling and proliferation of granular pneumocytes following intravenous booster injection.
The immunological pathogenesis was suggested by the demonstration of antibody in the sera to allogeneic soluble antigen by hemagglutination test.
The serum angiotensin I converting enzyme (ACE) activity was also tested. The injection of allogeneic soluble lung antigen caused significantly high serum ACE level compared with that of normal controls, and it was suggested that the high level of serum ACE was due to proliferation of macrophages in the alveolar space抄録全体を表示PDF形式でダウンロード (13973K) -
金井 興美, 近藤 瑩子, 保田 友義1980 年 55 巻 5 号 p. 241-245
発行日: 1980/05/15
公開日: 2011/05/24
ジャーナル フリーIn response to mycobacterial infection, the alveolar epithelium of mice revealed some ultrastruc tural changes. Particularly, Type II epithelial cells increased in number, more than one being often found in a single alveolus. Their proliferation was indicated by mitotic figures. Their characteristic lamellar inclusions showed sometimes abnormal morphology.抄録全体を表示PDF形式でダウンロード (7960K) -
亀田 和彦, 川幡 誠一, 白井 誠一1980 年 55 巻 5 号 p. 247-251
発行日: 1980/05/15
公開日: 2011/05/24
ジャーナル フリーA 62 years old male who suffered from acute hepatitis soon after starting the treatment with isoniazid, ethambutol and rifampicin for pulmonary tuberculosis was reported.
For 2 weeks before admission, isoniazid and ethambutol were given without any abnormal sign, butassoon as rifampicin was added after admission, thepatient suffered from nausea, loss of appetite, vomiting and headache, and thereafterjaundice and coma appeared with serum transaminase level up to 900 units.
When isoniazid was resumed after his recovery, liver function again became abnormal. However as regimen of rifampicin associated with ethambutol was resumed, no manifestation of hepato toxicity was seen at all.
Abnormality of liver function was more freqeuntly found in cases treated with rifampicin plus isoniazid than in cases with rifampicin plus drugs other than isoniazid.
Disturhance of liver function under treatment with isoniazid and rifampicin was discussed.抄録全体を表示PDF形式でダウンロード (641K) -
平田 世雄1980 年 55 巻 5 号 p. 253-258
発行日: 1980/05/15
公開日: 2011/05/24
ジャーナル フリーTwo cases of tuberculosis exacerbation, both with calcified foci on the chest roentgenogram, in duced during treatment for different cancer are presented. One is a miliary tuberculosis affecting a 65-year-old female with relapsed breast cancer who had received adjuvant chemotherapy containing 5mg-a-day predonin for 28 days after radical mastectomy. The other case is a fibroproductive tuber culosis with cavity beneath the radiation fibrosis at the apex found in a 69-year-old male who had received left radical tonsillectomy with radiation five years ago and reirradiated three years ago because of emergence of abnormal shadow suspecting of lung metastasis.
As for M. tuberculosis sputum obtained by bronchoscopy were negative in both cases at the beginning, lung metastases were strongly suspected until tubercle was verified from bone marrow three weeks later prior to the admission on the first case and positive sputum for tubercle bacilli was obtained by bronchofiberscope one year later on the second case.
Particular emphasis has been laid on the risk of exacervation of lung tuberculosis in these patients with various cancer and dormant tuberculous foci when receiving anticancer therapy.抄録全体を表示PDF形式でダウンロード (7385K) -
松島 敏春, 副島 林造, 栗田 啓, 中嶋 健博, 藤井 芳郎, 原 義人1980 年 55 巻 5 号 p. 259-263
発行日: 1980/05/15
公開日: 2011/05/24
ジャーナル フリーA case of tuberculous patient with bronchial compression by thoracic vertebrae was reported. Atelectasis of the left lung by compression of left mediastinal lymph nodes appeared in 41-year-old woman with bronchial tuberculosis. As the left lung was gradually shrinking and rotating to left back, the trachea and right main bronchus was compressed by thoracic vertebrae. Dyspnea appeared due to narrowing of the right main bronchus, and the pneumonectomy of atelectatic left lung was performed resulting relief of the symptom.抄録全体を表示PDF形式でダウンロード (6048K)
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