巻号一覧
58 巻, 1 号
選択された号の論文の7件中1～7を表示しています
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重松 信昭, 小橋 修, 松葉 健一1983 年 58 巻 1 号 p. 1-9
発行日: 1983/01/15
公開日: 2011/05/24
ジャーナル フリーPDF形式でダウンロード (1631K) -
束村 道雄1983 年 58 巻 1 号 p. 11-14
発行日: 1983/01/15
公開日: 2011/05/24
ジャーナル フリーMycobacterium gadium Casal & Rey Calero 1974 (Tubercle, 55: 299-308, 1974) is a rapidly growing, scotochromogenic Mycobacterium, which exists in the “Approved Lists of Bacterial Names” (Int. J. Syst. Bacteriol. 30: 225-420, 1980). It was documented that the type strain ATCC 27726 (M. Casal 1066) was differentiated from all other rapidly growing, scotochromogenic mycobacteria and was considered to belong to a distinct species (Tsukamura, M. et al.: Int. J. Syst. Bacteriol. 31: 263-275, 1981). However, since it was described on a single strain by Casal and Rey Calero, it is desired to characterize the species using more strains. We received three additional strains from Prof. M. Casal and studied on four strains, including the type strain ATCC 27726.
The characters of the type strain are shown in Table 1, and characters useful for differentiating among rapidly growing, scotochromogenic mycobacteria are shown in Table 2.
The species M. gadium together with other three, Mycobacterium aurum, M. thermoresistibile and M. duvalii, are characteristic in their negative arylsulfatase activity after 14 days. Among rapidly growing, scotochromogenic mycobacteria, only these four species show a negative arylsulfatase activity after 14 days. Differentiation of M. gadium from M. aurum, M. thermoresistibile and M. duvalii is made as shown in Table 3.抄録全体を表示PDF形式でダウンロード (517K) -
特に発症および死亡要因について堀越 裕一, 花島 恒雄, 森田 武子, 白石 透, 近内 康夫, 早川 欽哉1983 年 58 巻 1 号 p. 15-20
発行日: 1983/01/15
公開日: 2011/05/24
ジャーナル フリーThe purpose of this report is to elucidate the present status of miliary tuberculosis. Material for this study was obtained by reviewing the annual of pathological autopsy cases in Japan, 1967-1976.
Results were as follows:
1) Autopsy cases in patients who died of miliary tuberculosis within 10-year period were 940 cases. The aged were predominant. 492 cases were of males, 444 cases were of females and 4 cases were of unknown sexuality. Autopsy cases within the latter 5-year period increased compared with those within the former 5-year period.
2) Non-miliary tuberculosis was present in 47% of all cases and non-tuberculous disease was present in 25% of them.
3) Corticosteroids were used in 30% of them, which were noted as the predisposing factor.
4) Miliary tubercles were distributed in several organs. Concerning their distribution in various organs in relation to age of patients, no remarkable difference by age was seen in liver, spleen and kidney. On the contrary, meninges were involved more frequently in small children and loss in the aged, and the involvement of bone marrow was higher in the aged and lower in small children.
5) Only 12% of all cases were correctly diagnosed before autopsy.
From the above results, importance of recognition of the changing feature of present miliary tuber culosis was emphasized.抄録全体を表示PDF形式でダウンロード (888K) -
第7報 リンパ節結核の易感染性稲本 元1983 年 58 巻 1 号 p. 21-24
発行日: 1983/01/15
公開日: 2011/05/24
ジャーナル フリーDialysis patients are known to be immunodeficient. To study their susceptibility to lymphnode tuberculosis, an epidemiological study was done.
The subjects consisted of 2, 034 dialysis patients in 1976 and 2, 403 patients in 1977. Among them 12 patients in 1976 and 25 patients in 1977 had tuberculous lesions in lymphnode.
Incidence of lymphnode tuberculosis was 233 per 10, 000 person-years in male and 804per 10, 000 person-years in female dialysis patients, which was 106 times in males and 122 times in females higher than the rate of the age-matched general population. The incidence was 3.5 times higher in female than that in male dialysis patients. Prevalence of the disease was 1.7 times and 2.3 times higher in female than those in male dialysis patients in 1976 and in 1977, respectively. Mean duration time of lymphnode tuberculosis among female dialysis patients was half of that among male dialysis patients. Mortality of lymphnode tuberculosis was 544 times higher in the dialysis patients than that in the general population.
Lymphnode tuberculosis occupied 16% in male and 35% in female of all tuberculosis developed during 1976 among the dialysis patients in contrast to 1.4% in male and 8.2% in female of the general population.
Thus, an extremely high susceptibility to lymphnode tuberculosis in dialysis patients was proved for the first time epidemiologically. Furthermore, the present study demonstrated a remarkably high frequency of lymphnode tuberculosis among all tuberculosis in dialysis patients.抄録全体を表示PDF形式でダウンロード (497K) -
川幡 誠一, 船越 正信, 亀田 和彦1983 年 58 巻 1 号 p. 25-31
発行日: 1983/01/15
公開日: 2011/05/24
ジャーナル フリーWe examined 140 patients with newly diagnosed pulmonary tuberculosis complicated with diabetes mellitus who were admitted during the period from 1977 to 1980. Out of these 140 cases, 88 culture positive cases with pretreatment drug sensitive strains were picked up and were compared with 87 control tuberculous patients without complicating diabetes. All of them were treated with SHR (or EHR) regimen.
1. Monthly culture results.
Regardless with presence or absence of diabetes and good or poor control, sputum culture converted to negative with similar speed. In all cases, culture converted to negative within 4 months after starting chemotherapy.
2. Evaluation of radiographic findings and their course by Gakken standard.
Kc (fresh multilocular) and Kd (tuberculem) type cavities were more frequently found in diabetic patients. But, good radiographic response to chemotherapy was obtained in both groups.
3. Follow up study after cessation of chemotherapy.
61 patients out of 88 diabetics were followed up for more than six months after the completion of chemotherapy. Nine out of 61 diabetics (14.8%) showed radiographic worsening and the rate was significantly higher than that of the patients without diabetes (1 out of 54 or 1.9%). However, only two (3.3%) of the diabetic patients relapsed bacteriologically. None relapsed bacteriologically in the control, but the difference in the relapse rate between these two groups was statistically not significant.
From our results, 9-12 months chemotherapy appears to be satisfactory even for pulmonary tuberculosis patients complicated diabetes.抄録全体を表示PDF形式でダウンロード (944K) -
持続排菌例の家族よりの患者発生に関する検討 (続報)亀田 和彦, 久池井 暢, 堀井 冨士子, 大塚 順子, 田中 麗子, 矢野 周子, 中原 歌子1983 年 58 巻 1 号 p. 33-37
発行日: 1983/01/15
公開日: 2011/05/24
ジャーナル フリーIn order to confirm our conclusion mentioned last year, that is-the contacts examination of chronics should thoroughly be carried out for the first three to four years after the discovery o f index cases, especially for infants and school children, and the same careful consideration should also be given to infants who were born after the index cases have become chronics-family contacts of chronics who were subjected to the study in the last year were investigated again in this year.
At this time 189 (66.3%) out of 285 were examined, but no new patient was found among the whole family contacts including 19 infants and school children who were born after the index cases have become chronics. Four out of 74 infants and school children were diagnosed as primarily infected, but all cases would have been found earlier if examination had been given for at least three to four years after the discovery of index cases.
Based on the results of the study, it can be said that above mentioned recommendation for contacts examination of chronics is reasonable.抄録全体を表示PDF形式でダウンロード (756K) -
田中 渥1983 年 58 巻 1 号 p. 39-51
発行日: 1983/01/15
公開日: 2011/05/24
ジャーナル フリーMDPはモルモット腹腔浸出マクロファージのDNA複製を強く抑制した. この抑制はマクロファージ活性化に伴つて起こる現象であることが示唆された. おそらく, MDPによるマクロファージの強い活性化はより強い細胞への分化の始まりと思われる.抄録全体を表示PDF形式でダウンロード (7134K)
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