Kekkaku(Tuberculosis)
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
Volume 58, Issue 4
Displaying 1-5 of 5 articles from this issue
  • [in Japanese], [in Japanese]
    1983 Volume 58 Issue 4 Pages 235-245
    Published: 1983
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
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  • Michio TSUKAMURA
    1983 Volume 58 Issue 4 Pages 247-250
    Published: 1983
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    Sulfadimethoxine inhibited growth of strains of Mycobacterium avium-M. intracellulare complex at a concentration of 1 to 10μg/ml, and Kitasamycin inhibited its growth at a concentration of 2.5 to >20μg/ml. These agents may be tried clinically as chemotherapeutic agents, together with minocycline which was reported as effective previously, in the treatment of lung disease due to this organism.
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  • 9. Bone and Joint Tuberculosis
    Hajime INAMOTO
    1983 Volume 58 Issue 4 Pages 251-254
    Published: 1983
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    Patients undergoing maintenance hemodialysis show impaired immunity. In order to clarify the characteristics of bone and joint tuberculosis in dialysis patients, an epidemiological study was made.
    Study subjects were 7, 274 dialysis patients including 150 cases complicated with tuberculosis treated in 161 institutions, and among them 4 males and 4 females had bone and joint tuberculosis. They were aged between 21 and 53, and the majority were in the age groups 40s and 50s. Two males and two females died from tuberculosis.
    Incidence of bone and joint tuberculosis was 76 case/105 persons·Eyear in males and 140 in females. The mortality rate was 38 case/105 persons·Eyear in males and 70 in females. The fatality rate was 50% both in males and in females. Incidence of tuberculosis localised solely in bone and joint was 12 case/105 persons·Eyear in dialysis patients, which was 5 times higher than that of the age and sex matched general population.
    Bone and joint tuberculosis occupied 4.8% in males and 7.5% in females of all tuberculosis among dialysis patients. Deaths from bone and joint tuberculosis occupied 13% in males and 20% in females of all deaths from tuberculosis in dialysis patients.
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  • Joichi KONISHIIKE, Toshiko ASAHI, Nobuhiko KITA, Kunihiko YOKOYAMA, Yo ...
    1983 Volume 58 Issue 4 Pages 255-265
    Published: 1983
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    According to the review of the past literatures, the chemotherapy for silico-tuberculosis in the earlier days was almost unsuccessful.
    The present paper reports the follow-up studies of all the originally or retreated cases with silicotuberculosis, 140 in number, admitted to our hospital during the past 28 years (1953-1980).
    The results were summarized as follows:
    1. Fourty-three previously untreated cases with positive sputum for tubercle bacilli, were treated with the combination of primary antituberculous drugs, SM, INH, and PAS. The negative conversion of tubercle bacilli in sputum was seen in 40 cases (93.0%), however, the bacteriological relapse was observed in 11 cases (27.5%) within three years.
    2. Sixty-one previously treated cases with positive sputum for tubercle bacilli, were treated with regimens containing primary and/or secondary antituberculous drugs. Only 30 cases (49.2%) converted to negative, while the others showed continuous bacilli discharge.
    3. The rate of bacteriological relapse before the introduction of RFP was higher in silico-tuber culosis than in tuberculosis of similar extent without complicating silicosis.
    These results indicate that bacteriological relapse is the important factor causing clinical aggravation of the disease.
    4. The effects of intensive chemotherapy regimens containing RFP at the initial stage of treat ment were studied in 26 originally treated cases.
    The negative conversion of tubercle bacilli in sputum was reached revealed in 100% of cases within 5 month and continued until 34th month on the average after starting chemotherapy.
    5. It is conceivable that an intensive chemotherapy regimens containing RFP for originally treated cases makes it possible to control and cure silico-tuberculosis as well as to shorten the duration of chemotherapy.
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  • Kiyohiko HATAKE, Ken SAITO, Shotaro OZAWA
    1983 Volume 58 Issue 4 Pages 267-270
    Published: 1983
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    We present a male case with pulmonary tuberculosis who developed ileal perforation during antituberculous therapy. A 30 year-old man was admitted to our department in September 1979. He had a three-month history of night sweating and slight fever. Tubercle bacilli were demonstrated on light microscopy from his sputa. We started treatment using RFP, EB, and INH. Four months after starting treatment he complained of abdominal pain, and laparotomy was performed. We observed ileal perforation with surrounding adhesion. Histopathologic examination of resected ileum and mesenteric lymph nodes showed chronic ulcer and granuloma with Schaumann body in ileal submucosa, and presence of giant cell with asteroid body. There was no foci with caseous necrosis. These findings were also compatible with sarcoidosis, but good response to antituberculous therapy or absence of bilateral hilar lymphadenopathy of the lung lead us to the result of ileal tuberculosis.
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