All issues
Volume 60, Issue 6
Displaying 1-5 of 5 articles from this issue
- |<
- <
- 1
- >
- >|
-
[in Japanese]1985 Volume 60 Issue 6 Pages 343-350
Published: June 15, 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSDownload PDF (1142K) -
FOR MORE THAN FIVE YEARS AT THE SURVEY OF 1975 (Part 1)The Tuberculosis Research Committee RYOKEN1985 Volume 60 Issue 6 Pages 351-360
Published: June 15, 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSAt the survey on October 15th, 1975, a total of 1936 patients had stayed at hospitalsfor more than five years and out of them, 1574 patients (81.3%) were followed till June, 1981. Out of 1574 patients, 501 (31.8%) were still staying at hospitals, 566 (36.0%) haddied and 498 (31.6%) were discharged from hospitals, as 48 (9.6%) died after the discharge, a total number of death reached 614 patients (39.0%.)
The death rate was higher in aged patients 41.5, in patients with positive sputumfor tubercle bacilli (53.6%), in patients with pulmonary failure (71.2%), especially inpatients both with positive tubercle bacilli and dyspnea 85.7, in advanced cases (53.9%) and in patients who had been treated by many drugs (47.6%).
Death from tuberculosis occured in 437 patients (71.2%) and 143 patients (23.3%) died of non-tuberculous diseases and 34 (5.5%) due to unknown causes. Although theproportion of death from tuberculosis was almost similar in all the age groups excepteighty years and more death due to non-tuberculous diseases increased with age, and itexceeded death from tuberculosis in the age group 80 years and more.
During the first year of follow-up study, the death rate from tuberculosis was 6.5%and that from non-tuberculous disease was 2.1%. Accumulated death rate for six yearswas 27.4% for tuberculos is, 8.8% for non-tuberculous diseases and the total death ratewas 36.2%.
Out of 498 patients who were discharged during six years, 28 patients (5.6%) showedconstantly positive sputum for tubercle bacilli and 15 patients (3.0%) discharged ocasionally tubercle bacilli.
Patients who are working or stopped treatment after the discharge were observedmore frequently among those who showed cirrotic lesions on chest X-ray and had nocomplaint of dyspnea.View full abstractDownload PDF (1202K) -
Hiroshi SATO, Ken SATO, Masako SASAKI, Kotaro OIZUMI, Masakichi MOTOMI ...1985 Volume 60 Issue 6 Pages 361-364
Published: June 15, 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSOut of 1592 primary lung cancer cases who were confirmed by the histological findings, 101 cases (6.3 %) had been treated as pulmonary tuberculosis before the final diagnosis was made as lung cancer.
Sixty percent of these patients were detected by the mass survey and 49% of themwere adenocarcinoma.
Treatment for tuberculosis had been stopped within 3 months in 50% of these cases, while treatment by anti-tuberculous drugs had been continued for more than 13 monthsin 15%.
The duration of the treatment as tuberculosis was longer in cases detected by themass survey and showing abnormal shadows in peripheral lung field on chest X-ray film, than in other cases.View full abstractDownload PDF (562K) -
Michio TSUKAMURA, Eiichi NAKAMURA, Saiji YOSHII, Masayuki YANASE, Yuki ...1985 Volume 60 Issue 6 Pages 365-369
Published: June 15, 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSThe therapeutic effect of a new antibacterial substance ofloxacin (DL 8280) is reportedbased on the data of one year-administration for 16 treatment-failure patiants with pulmonary tuberculosis. All patients had chronic cavitary lung tuberculosis with the disease history of 3 to 25 years. The study started with 19 patients, but three patients died until the 8thmonth due to cor pulmonare. These three patients were not included in the data of this study. The remaining 16 patients received oral administration of ofloxacin (DL 8280) as a single daily dose of 300mg. A few antituberculosis agents, which failed to bring in the bacilli negative conversion were used in combination.
The culture positivity was reduced markedly by the adrrinistrati on of ofloxacin (Table1 and Fig.1).
The negative conversion of tubercle bacilli in sputum cultures occurred in three patients, cases no.2, 5 and 19 (Table 1). Another one patient (case no.3) also seemed to havereached the negative conversion, as the patient showed negative culture until the fourteenthmonth of the observation (Table 1 shows the results until the twelfth month). Case no. 1had orice the negative conversion, but later showed occasional excretion of small amounts (1 to 10 colonies) of tubercle bacilli (Table 1).
Improvement of the x-ray feature (reduction of cavity size) was observed in 5 patients (cases no. 2, 3, 5, 7 and 12), and increase of body weight more than 4 kg in four patients (cases no. 3, 4, 5 and 19).
The resistance of tubercle bacilli to ofloxacin appeared in the the third or fourth monthof administration (Table 2).
No side effects were observed during during the administration period of one year. Nopathologic findings were observed in the following examinations: Blood cell counts; amount of hemoglobin; leucocyte components; amounts; amounts of inorganic ions in serum; serum-transamidase activities; alkaline phosphatase activity in serum; amount of ureanitrogen and creatinine in the serum; amounts of protein, sugar and sediments in theurine.
In conclusion, ofloxacin (DL 8280) has been considered to be an effective agent forthe treatment of pulmonary tuberculosis.View full abstractDownload PDF (585K) -
Hitoshi TERASAKI, Shuichi OKUBO, Shinichi ODAMA, Yasuyuki YOSHIZAWA, H ...1985 Volume 60 Issue 6 Pages 371-377
Published: June 15, 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSThe incidence of tuberculous peritonitis has been decreasing since the introduction ofspecific chemotherapy against Mycobacterium tuberculosis.
The diagnosis of tuberculous peritonitis is often missed in the differential diagnosis ofabdominal disorders, especially when chest X-ray abnormalities consistent with tuberculosis are absent. Hence the start of antituberculous chemotherapy is often delayed.
Recently we have experienced a case of tuberculous peritonitis and pleurisy: 41 yearsold female who complained abdominal distention, slight fever, night sweats and weight loss.Chest X-ray revealed bilateral pleural effusion. Tuberculin skin testing was negative.Lymphocytic exudative ascites was observed. Barium-enema finding was normal.The diagnosis of tuberculosis was made early on the histological findings from the specimens with percutaneousperitoneal biopsy.The bacteriological culture revealed positive for Tb. bacilli in both ascitesand pleural fluid.
Seventy-six cases of tuberculous peritonitis were reported in Japan between 1978 and1982, and the female/male ratio was 3: 2. Chest X-ray revealed abnormality suggestive of tuberculosis in only 28%, and pleural effusion was present in 30%, of all cases.
Tuberculin skin testing was negative in 32% of cases. The prognosis of tuberculous peritonitiswas fairly good. Only 3 (4%) out of these 76 cases died.Tuberculous peritonitis should be considered in the differential diagnosis in patientswith abdominal disorders, and the diagnosis should be confirmed early by laparoscopyand peritoneal biopsy.View full abstractDownload PDF (5659K)
- |<
- <
- 1
- >
- >|