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Volume 60, Issue 7
Displaying 1-6 of 6 articles from this issue
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Hiroshi SAKURAI, Yoshimasa WATANABE, Masaaki YAMANAKA, Toshikatsu MORI ...1985 Volume 60 Issue 7 Pages 381-388
Published: July 15, 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSWe investigated 127 patients of culture-positive pulmonary tuberculosis complicated with diabetes mellitus (92 cases of initial treatment and 35 cases of retreatment) who were admitted to our hospital during the period from 1977 to 1983, and then obtained the following results:
1. The initial treatment group of tuberculosis with diabetes was predominant in terms of older ages, highly positive cultures and extensive lesions demonstrated roentgenographi callv, when compared with the similar group without complicating diabetes as control.
2. In all the 88 patients of tuberculosis with diabetes who were treated initially with combination regimens including INH and RFP known to be susceptible, sputum cultures converted to negative within 4 months irrespective of good or poor control of complicating diabetes, and thereafter no bacteriological relapse was observed by follow-up study.
3. The retreated diabetic group consisted of a considerable number of advanced patients who expectorated organisms resistant to multiple drugs and showed a poor clinical response to treatments.
However, in 19 cases having susceptibility to INH and RFP, negative smears and cultures were eventually attained independently of the severity of tuberculous lesions as well as the efficiency of control of diabetes, and a bacteriological relapse was found in only a single case by follow-up.
4. The cases treated with regimens excluding INH and RFP (4 cases of initial treatment and 16 cases of retreatment) showed an extremely poor response to the chemotherapy.
5. Although the effectiveness of chemotherapy with regimens including INH and RFP which had been confirmed to be susceptible was very satisfactory suitable duration of chemotherapy has to be studied further.View full abstractDownload PDF (848K) -
From The Experience During The Past 10 YearsShu HASHIMOTO, Yoshifumi HOSOKAWA, Koichi KAWAMURA, Takashi YOSHINOBU, ...1985 Volume 60 Issue 7 Pages 389-395
Published: July 15, 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSIn order to make clear the actual conditions of tuberculosis patients at university hospitals and the significance of T.B. wards there, a survey was conducted with the patients as hospitalized in the T.B. ward of Itabashi Hospital, Nihon University, School of Medicine, during the 10 years from October 1973. The patients were studied classified for each year by sex. age, drug, onset, complication and outcome to obtain the following findings:
1. In and after 1976 when the short-term chemotherapy based on RFP became the main treatment, the number of patients increased and the days of hospitalization decreased, temporarily. This trend has however been brought to normal soon.
2. There was seen no particular tendency in the age composition of T.B. patients from year to year.
3. There were good many patients who were examined and treated by the Respiratory Organ Dept. in cooperation with some other departments. We consider that 61 cases of total tuberculous patients (18.5% of the total) were those with compro mised host, of which 31 cases (9.4%) were with diabetes mellitus and 9 cases (2.7%) developed the disease while they were under the steroidal therapy.
4. Although T.B. wards at universities are not without some managerial problems, such are considered advantageous for the examination/ treatment of patients with complications, at the time of onset of disease in easily-infected hosts and also by way of training students and interns.View full abstractDownload PDF (794K) -
The Tuberculosis Research Committee RYOKEN1985 Volume 60 Issue 7 Pages 397-403
Published: July 15, 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSThose who still continued to stay in hospitals untill June of 1981 were 501 patients. Out of them, 136 patients (27.1%) expectorated tubercle bacilli constantly, 50 patients (10.0%) occasionally, and tubercle bacilli were negative in 307 patients (61.3%)
Tubercle bacilli were found frequently in those who were under 49 years old (47.0%), positive sputum at 1975 (87.8%), advanced cases (53.1%) and already used manydrugs (57.4%).
Vital capacity of 14 patients (2.8%) was 80% or more of predicted, while in 297 patients it was 49% or under of predicted and it was unable to measure for 50 patients. There were tendency that pulmonary failures were often observed in younger pat ients.
How many patients had diseases in addition to tuberculosis was investigated on the patients in hospitals. Respiratory diseases beside tuberculosis were found in 222 patients (44.3%) and diseases of fhe other organs were found in 225 patients (44.5%) and none was found in 142 patients (28.3%). Extra-respiratory diseases were found frequently in older ages and it was 71.2% in 70 years and older patients.View full abstractDownload PDF (784K) -
Hiroki HARA, Toshiharu MATSUSHIMA, Michifumi ADACHI, Susumu YAGI, Hiro ...1985 Volume 60 Issue 7 Pages 405-410
Published: July 15, 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSAs the result of an analysis on the process of diagnosis in 374 lung cancer patients who visited to our hospital in last 10 years, more than three months were needed to be diagnosed as lung cancer in 90 (30%) patients in the hospitals. Among them, 36 patients had been confused and treated as tuberculosis before visit to our hospital. So we studied on the frequency of the symptoms among the groups of 1) 374 lung cancer patients, 2) 36 lung cancer patients who had been treated by antituberculous chemotherapy, 3) 34pulmonary tuberculous patients who admitted in 1980 and 1981, and 4) 33 patients with lower lung field tuberculosis.
In consequence, the character and frequency of symptoms are mostry similar in these four groups, but there was the tendency that X-ray detection in cancer patients and symptoms in tuberculous patients were slightly often. It is considered to be difficult to discriminate between lung cancer and pulmonary tuberculosis by these symptoms or chest X-ray films, so it seems to need the farther valuable examinations in suspicious patients.View full abstractDownload PDF (630K) -
Yasuhito HONDA, Yuji IKEDA, Fumiko MITO, Eiichi SAKAI, Tadashi KUWAJIM ...1985 Volume 60 Issue 7 Pages 411-414
Published: July 15, 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSThe patient was a 76-year-old man who had been administered antituberculous drugs for active tuberculosis from July, 1979. In November, 1981, he complained of cough and fever, and on chest X-ray film infiltrative shadows newly appeared in the cavity of left upper lung field. M. fortuitum. was repeatedly isolated from sputum over one year, and diagnosed as a pulmonary infection due to M. fortuitum. This organism was completely resistant to all antituberculous drugs, but disappeared in March, 1981, probably by the therapy of AMK for 40 days. Three months after the disappearance of M. fortuitum M. tuberculosis appeared in his sputum. This case was a very interesting one for considering the complicated interaction between the immunity of host and the strength of M. fortuitum and M. tuberculosis in the cavity as a localized lesion.
Pulmonary fibrosis appeared in the course of M. fortuitum pulmonary infection, but this correlation was not apparent.
When considering M. fortuitum pulmonary infection as a one of opportunistic infection we emphasize the importance of investigation from the immunological viewpoint.View full abstractDownload PDF (3151K) -
Hiromichi TASAKA, Yoshiyasu MATSUO1985 Volume 60 Issue 7 Pages 415-417
Published: July 15, 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSTwo hundred and eight strains of clinical isolates of mycobacteria from Tokyo University Hospital, National Sanatrium Hiroshima Hospital, Hiroshima University Hospital and related hospitals were serologically identified with the use of absorbed anti-alpha antibodies against Mycobacterium kansasii, M. marinum, M. scrofulaceum, M. gordonae, M. szulgai, M avium, M. intracellulare and M. tuberculosis. The results were compared with those obtained by biochemical identification. Co incidence ratio by the two methods was 87.3 per cent.View full abstractDownload PDF (226K)
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