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Volume 61, Issue 6
Displaying 1-5 of 5 articles from this issue
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Akiko TAKAI, Hitoshi MUROMOTO, Masahiko KURATA, Akira NAGAI, Tsunesuke ...1986 Volume 61 Issue 6 Pages 327-331
Published: June 15, 1986
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSSingle radial immunodiffusion technique using complement film was applied to tuberculous patients in order to evaluate its diagnostic value comparing with the traditional test tube technique (modified Ogata's method). As mycobacterial antigen for the reaction unheated tuberculoprotein was prepared from viable BCG cells.
Single radial immunodiffusion technique using complement film was applied totuberculous patients in order to evaluate its diagnostic value comparing with the traditional test tube technique (modified Ogata's method). As mycobacterial antigen for the reaction unheated tuberculoprotein was prepared from viable BCG cells.
Because of its technical simplicity, the single radial immunodiffusion method using complement film will be worthy of routine use for the differential diagnosis of tuberculosis.View full abstractDownload PDF (528K) -
(1) Delayed Therapy of Murine InfectionNobuo SAKURAI, Fumiyuki KUZE1986 Volume 61 Issue 6 Pages 333-339
Published: June 15, 1986
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSA murine chronic model of M. avium-intracellulare infection was established in our labolatory and reported at the 58th annual meeting. The evaluation of therapeutic effects of some regimens against the murine chronic model has been studied, and the several multidrug regimens including Kanamycin (KM) revealed to be effective.
In the previous experiments, however, the treatments were uniformly begun one week after infection. This time, the treatments were begun immediately, two weeks and four weeks after infection, and the evaluation of the effects was done by observing the macroscopic lesions of each organ, weighing the lungs, spleens, kidnies and livers, and counting the number of viable bacilli per lung and spleen. The regimens used in this experiment were KM-Rifampicin (RFP)-Ethambutol (EB) and KM-RFP-EB-Cyclocerine (CS)-Ethionamide (TH).
The two regimens, even when they were given four weeks after infection, were found effective in the macroscopic lesions, weights and viable counts of bacilli of the organs. The effect of delayed treatments was almost the same as that of the immediate therapy. The difference between these two regimens was, however, not significant.View full abstractDownload PDF (829K) -
Fumiyuki KUZE, Nobuo SAKURAI, Fumiaki OGINO, Shinichi TOGAWA1986 Volume 61 Issue 6 Pages 341-349
Published: June 15, 1986
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSDownload PDF (1187K) -
Hironobu IWASAKI, Nobuyuki KATAKAMI, Hiroko SAKAMOTO, Eitetsu LEE, Kyo ...1986 Volume 61 Issue 6 Pages 351-355
Published: June 15, 1986
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSWe reported a case with pulmonary tuberculosis who developed ileal perforation
A 35 year-old man was admitted to our hospital in September 1984 with severe dyspnea. Chest X-ray revealed massive bilateral pleural effusion and tubercle bacilli was demonstrat ed from the pleural effusion. We started treatment using SM, INH and RFP. Six days after starting treatment he complained of abdominal pain and the sign of peritonitis developed. Emergency laparotomy was performed and we observed ileal perforation and miliary dissemination of tuberculous nodules over the peritoneum. Histopathologic examination of resected ileum showed ulcers and epitheloid granuloma with caseous necrosis. Acid-bacilli were demonstrated from the lesion by special-stained tissue sections.
Perforation of the intestinal tuberculosis is rare in recent years but we should keep in mind as possible cause of the acute abdomen.View full abstractDownload PDF (1601K) -
Comparison of Antimycobacterial Spectra between Ofloxacin and CiprofloxacinMichio TSUKAMURA, Shoji MIZUNO1986 Volume 61 Issue 6 Pages 357-359
Published: June 15, 1986
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSSenior author studied previously on the susceptibility of various mycobacteria to ofloxacin (Tsukamura, M.: Microbiol. Immunol. 27: 1129-1132, 1983) and reported that the susceptibility tests to the agent are useful for differentiating M. nonchromogenicum from M. terrae-M. triviale, and for differentiating M. fortuitum from M. chelonae. In the same study, high susceptibilities of M. tuberculosis, M. bovis, M. kansasii, M. xenopi and M. fortuitum also were reported. In the present study, we studied on the susceptibility of various mycobacteria to an analogue, ciprofloxacin, and found that the antimycobacterial spectra of ofloxacin and ciprofloxacin are the same and their antimycobacterial activities also are the same. The susceptibility tests for these agents are useful for differentiating some important pathogens of mycobacteria.View full abstractDownload PDF (354K)
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