巻号一覧
62 巻, 12 号
選択された号の論文の8件中1～8を表示しています
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村西 寿一, 中島 道夫, 恒松 英明, 重松 信昭, 磯部 隆一1987 年 62 巻 12 号 p. 627-633
発行日: 1987/12/15
公開日: 2011/05/24
ジャーナル フリーMass chromatogram of gas chromatography/mass spectrometry (GC/MS) was used to detect 10-methyloctadecanoic acid (tuberculostearic acid, denoted TSA hereafter) which is known as characteristic fatty acid of acid-fast bacteria of order Actinomycetales. The analysis was performed on 5-7-day-old cultures of sputum specimens from 18 patients with pulmonary tuberculosis (TB) and non TB. Fatty acids extracted from cultures were converted to methyl ester then purified by thin-layer chromatography prior to subjecting to the GC/MS analysis. The average turn over time was 10 day, and this is much shorter than ordinary culture method of 4-8 weeks. TSA was detected in three of four specimens from TB patients and in all four from atypical mycobacteriosis patients, already diagnosed, but neither in six from non TB patients nor in four from obsolete pulmonary TB patients. The relative sensitivity and specificity were 87.5% and 100%, respectively. Since only two of above TSA positive specimens were culture (8 wks) positive, the high intrinsic sensitivity of this method is emphasized.抄録全体を表示PDF形式でダウンロード (779K) -
中俣 正美, 月岡 一治, 近藤 有好, 橋本 正1987 年 62 巻 12 号 p. 635-639
発行日: 1987/12/15
公開日: 2011/05/24
ジャーナル フリーWe studied plasma ADH (antidiuretic hormone) in 92 patients with pulmonary tuberculosis.Abnormally high plasma ADH was observed in 27 patients. PaO2 was less than 60mmHg in 25 out of these 27 patients, and other 2 had wide spread tuberculous lesion. Abnormally high plasma ADH was observed more frequently in the patients with hypercapnic acidosis than in the patients with eucapnic respiratory failure. In the majority of the patients, relation between osmotic pressure and ADH was in the reasonable range. There was no relation between plasma ADH and activity of pulmonary tuberculosis.
It was suggested that abnormally high plasma ADH in the patients with pulmonary tuberculosis was caused mainly by the reaction against abnormal arterial blood gases and partially by reduced blood flow in the pulmonary vessels damaged by tuberculosis or by respiratory failure.
2 patients were suspected of SIADH (syndrome of inappropriate secretion of ADH), although abnormally high plasma renin activity was observed in 2 patients. Furthermore, high plasma ADH may thought to be a reaction. Therefore some discussion will be required that these patients are true SIADH or not.抄録全体を表示PDF形式でダウンロード (586K) -
原 宏紀, 沖本 二郎, 藤井 芳郎, 原 義人, 中嶋 健博, 松島 敏春1987 年 62 巻 12 号 p. 641-645
発行日: 1987/12/15
公開日: 2011/05/24
ジャーナル フリーBy X-ray mass screening of a total of 1, 134, 532 participants during a six year period from April, 1980 to March, 1986, 385 were suspected of lung cancer. One hundred and thirty-five cases out of these 385 cases were diagnosed as lung cancer, and 67 cases underwent thoracotomy. To evaluate the efficacy of X-ray mass screening, we studied the histological type, clinical stage, tumor size, location, and the period from screening to resection.
Many of these resected cases were peripherally situated adenocarcinoma in early clinical stage. The interval from screening to thoracotomy, ranged from 17 to 165 days (average 52.1 days), and in17 cases (28.3%), it was30days or less. However, there were 17 cases in which the interval was more than 60 days. The reason for such a delay was the difficulty in diagnosis. If good communication and cooperation were established between medical staff and patients, it seems possible to resect of lung cancer shortly after the detection.抄録全体を表示PDF形式でダウンロード (635K) -
石橋 凡雄, 原田 泰子, 高本 正祇, 原田 進, 北原 義也, 篠田 厚1987 年 62 巻 12 号 p. 647-654
発行日: 1987/12/15
公開日: 2011/05/24
ジャーナル フリーThe present study was undertaken to enumerate the proportion and absolute number of various lymphocyte subsets in the peripheral blood of 119 normal healthy adults using combination of monoclonal antibodies and two color flow cytometry.
The results obtained were as follows:
1) The proportion and absolute number of pan T cells (Leu 4+) was significantly lower in the eldest group more than 70years of age. The proportion but not the absolute number of helper T cells (Leu3+8-) was significantly higher in the age groups over 50, whereas the absolute number of inducer T cells (Leu3+8+) was lower in the eldest group. The absolute number of suppressor/cytotoxic T cells (Leu2+) was significantly lower in the eldest group. However the proportion and absolute number of suppressor T cells (Leu2+15+) was not influenced by age. The ratio of T4/T8 (Leu3/Lou2) cells tends to increase with age.
2) The proportion and absolute number of B cells (Leu 4-DR+) was not influenced by age.
3) Among the natural killer cell subsets, the proportions but not the absolute numbers of Lou7+ cells and Leu11+ cells were significantly higher in the eldest group. The proportion and the absolute number of Lou 11+7- cells was not influenced by age, whereas both values of Lou 11+7+ cells were significantly higher in the eldest group. The proportion and absolute number of Lou 11-7+ cells was clearly lower in the youngest group. The absolute number of Lou 7+2+ cells was also lower in the youngest group.抄録全体を表示PDF形式でダウンロード (1066K) -
山岸 文雄, 鈴木 公典, 村木 憲子, 伊藤 隆, 佐藤 展将1987 年 62 巻 12 号 p. 655-659
発行日: 1987/12/15
公開日: 2011/05/24
ジャーナル フリーA 23-year-old man was found to have bilateral hydrothorax by a physical checkup, and admitted to a hospital, where he was medicated with adrenocortic al hormones because of the presence of persistent fever, but not in combination with antituberculous agents. After about 6 weeks, he fell into acute respiratory failure and was equipped with respirator after tracheotomy. Later on, thoracic fluid culture revealed positivity of M. tuberculosis. Therefore, this patient was transferred to our hospital when his general condition was improved to tolerate the transport.
Because his fever persisted after admission to our hospital, transbronchial lung biopsy was performed, and Ziehl-Neelsen stain showed a large number of acid-fast bactilli. Therefore, he was diagnosed as miliary tuberculosis, and then successfully treated with antituberculous agents.
Although this patient was discharged after abatement, his respiratory failure was so severe that a single misstep would have been followed by death. The administration of adrenocortical hormones without use of antituberculous agents, even though the presence of persistent fever, seemed to be thoughtless.抄録全体を表示PDF形式でダウンロード (6119K) -
II. 基礎疾患を有する患者への抗結核薬の投与青柳 昭雄1987 年 62 巻 12 号 p. 661-684
発行日: 1987/12/15
公開日: 2011/05/24
ジャーナル フリーPDF形式でダウンロード (3292K) -
厚生省保健医療局結核難病感染症課編1987 年 62 巻 12 号 p. 685-686
発行日: 1987/12/15
公開日: 2011/05/24
ジャーナル フリーPDF形式でダウンロード (275K) -
1987 年 62 巻 12 号 p. e1
発行日: 1987年
公開日: 2011/05/24
ジャーナル フリーPDF形式でダウンロード (162K)
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