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Volume 63, Issue 6
Displaying 1-6 of 6 articles from this issue
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Michio TSUKAMURA1988 Volume 63 Issue 6 Pages 433-439
Published: June 15, 1988
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSThe occurrence of infection due to M.ulcerans is restricted to three area, South America, Africa, and Oceania including Malaya.Recently, Hayman has proposed ahypothesis that these areas had formed one group in Jurassic time and at that time M.ulcerans developed and has survived until now in these areas after separation of thesecontinents.Recently, we have found one case of infection due to a variety of M.ulcerans (M.ulcerans subsp.shinshuense) in this country.This occurrence is understood if weconsider that Japan is located in the northern end of the Oceania area.M.haemophilum isa mycobacterium which requires hemin for growth and its characteristics are very similarto those of M.avium complex except for its requirement of hemin and its growthtemperature limited to 28-30°C.Infection due to this organism is found most frequentlyin Australia but also in Israel, France and U.S.A.View full abstractDownload PDF (901K) -
THE EVALUATION OF ADA ACTIVITY IN PLEURAL EFFUSION FOR THE DIAGNOSIS OF TUBERCULOUS PLEURAL EFFUSIONShang-Jyh KAO, David WANG, Feng-Yee CHANG, Kang HSU, Chien-Yeh SHEN, J ...1988 Volume 63 Issue 6 Pages 441-446
Published: June 15, 1988
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSPleural effusion from 59 cases of various diseases were studied by high pressure liquidchromatography (HPLC) in order to evaluate the diagnostic value of measurement ofadenosine deaminase (ADA) activity.Patients were divided into 4 groups: (1) 18 cases oftuberculosis; (2) 5 cases of bacterial empyema; (3) 22 cases with malignancies; (4) 14miscellaneous group cases including uremia, cirrhosis of liver, congestive heart failure andsystemic lupus erythematosus.The mean ADA activity was 110.79±33.85U/L in group1, 207.55±65.82U/L in group 2, 33.43±11.80U/L in group 3, and 25.53±9.30U/L ingroup 4.Comparing the levels obtained in each group, significant differences (p<0.001) were found between the tuberculosis group and both the malignancies and miscellaneousgroups.The empyema group also showed significant differences (p<;0.001) in comparisonto both the malignancies and miscellaneous groups.The sensitivity (100%) and specifity (87.8%) of the test in tuberculosis were very high when a value of more than 60U/L wasemployed as a diagnostic standard.View full abstractDownload PDF (633K) -
Nobuo SAKURAI1988 Volume 63 Issue 6 Pages 447-460
Published: June 15, 1988
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSThe therapeutic effect of five agents: sulfamethoxazole-trimethoprim (ST), minocycline (MINO), cefmenoxime (CMX), streptomycin (SM) and amikacin (AMK) and fourthree-drug-regimens: kanamycin (KM) rif ampicin (RFP)-ethambutol (EB), KM-CMXMINO, KM-RFP-ST and MINO-leucomycin (LM)-sulfadimethoxine were evaluated invivo for ddY or BALB/c mice infected intravenously with Mycobacterium avium-intracellulare, 31F093T strain.These drugs were all administered to the animals five daysa week in dosages roughly comparable with clinical use from 1 wk of infection.Themacroscopic lesions, the weights of organs and the counts of viable bacilli in lungs, spleenand kidneys were observed every three weeks during treatment (9 weeks).
KM and AMK (both in single use), and three three-drug-regimens (KM-RFP-EB, KM-CMX-MINO and KM-RFP-ST) exerted suppresive effect of macroscopic lesions andviable count of bacilli in the lungs.However, MINO, CMX and SM (all in single use) anda three-drug-regimen: MINO-LM-sulfadimethoxine demonstrated only slight tendancy ofsuppresion of macroscopic diseases and viable counts of bacilli in the lungs.Observationsof viable counts of bacilli in spleeen and kidneys showed almost the same tendencies.
In these experiments, AMK that was one of aminoglycosides had the same therapeuticeffect as KM on murine M.avium-intracellulare infection.And CMX, MINO and ST couldalso exerted therapeutic effect if they were used as a combined drug in multiple-drugregimens.These drugs might be taken into consideration in the therapy of human M.avium-intracellulare infection.View full abstractDownload PDF (1576K) -
Kikuo HIDA1988 Volume 63 Issue 6 Pages 461-468
Published: June 15, 1988
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSA mass screening for both lung tuberculosis and cancer was conducted on 25, 800inhabitant of Yaizu City in 1986, and 77.9% participated to this screening and thirteentuberculosis patients (0.06%) were found.
X-ray examination for lung cancer was conducted on 81.7% of inhabitants over fourtyyears of age (18, 060) in the city.Cytoscreening of sputum was carried out on 638participants who were over fifty years of age with Brinkman Index 600 and over, and elevenpatients (74.6per 100, 000) were found including eight cases in the early stage of lungcancer.
In conclusion, the establishment of an integrated system of precise diagnosis of X-rayfilms, phathological diagnosis and cytodiagnosis is needed for mass screening of lungcancer.View full abstractDownload PDF (920K) -
Chest Disease Cooperative Study Unit, Tetsuya MATSUMOTO, Nobuaki IKED ...1988 Volume 63 Issue 6 Pages 469-474
Published: June 15, 1988
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSDownload PDF (808K) -
[in Japanese]1988 Volume 63 Issue 6 Pages 483-486
Published: June 15, 1988
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSDownload PDF (483K)
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