結核
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
63 巻, 9 号
選択された号の論文の6件中1~6を表示しています
  • 束村 道雄, 一山 智
    1988 年 63 巻 9 号 p. 597-600
    発行日: 1988/09/15
    公開日: 2011/05/24
    ジャーナル フリー
    Mycobacterium avium complex, Mycobacterium tuberculosis, Mycobacterium kansasii and Mycobacterium marinum strains were cultivated in a 10 ml-sample of Dubos liquid medium and the amount of growth and the number of viable units per mg wet weight of these bacteria were determined in two days-intervals. M. avium complex strains contained 108-109 viable units per mg wet weight, whereas other mycobacteria 106-107.The factors influencing this number of viable units per mg should be as follows: 1) The viability duration of individual bacteria; 2) the size of bacteria;3) the clumping of bacteria; 4) the specific weight of bacteria.M.kansasii exhibited long rods but the length of rods was at most twofold.The clumping of M. tuberculosis was most marked but this was until a clumping of several bacteria.The specific weight of bacteria differed not so significantly from each other ranging from 0.93 to 1.11.Therefore, the greatest number of colony-forming units of M.avium complex strains was considered to be due to their longer viability duration. Other bacteria probably die soon after their multiplication, but the M. avium complex bacteria might live longer than the others even after multiplication.
  • 佐藤 勝昌, 斎藤 肇, 冨岡 治明
    1988 年 63 巻 9 号 p. 601-604
    発行日: 1988/09/15
    公開日: 2011/05/24
    ジャーナル フリー
    In vitro antimicrobial activities of rifabutin (RFB) and rifampicin (RFP) against Mycobacterium tuberculosis, M. kansasii, M. scrofulaceum, M. avium complex, M. fortuitum and M. chelonae were evaluated using 7H10agar and 1% Ogawa egg medium. RFB showed appreciable antimicrobial activity against RFP-sensitive M. tuberculosis (MIC90=0.05μg/ml), M. kansasii (0.05μg/ml), M.scrofulaceum (1.56μg/ml), and M. avium complex (0.78μg/ml) when MICs were determined on 7H10 agar medium.The activity of RFB was higher than that of RFP in all organisms tested.In the case of both the antimicrobials, their MIC values against test organisms were considerably lower by using 7H10 agar medium instead of Ogawa egg medium.
  • 束村 道雄
    1988 年 63 巻 9 号 p. 605-610
    発行日: 1988/09/15
    公開日: 2011/05/24
    ジャーナル フリー
    The nocardiae which may cause disease in humans are Nocardia asteroides, N. nova, N. farcinica, N. brasiliensis and N. otitidis-caviarum. Of these, N. asteroides, N. nova and N. farcinica had previously been regarded as belonging to only one species, N. asteroides (Gordon and Mihm, 1957). In 1969, Tsukamura divided the N. asteroides species into two species, N. asteroides sensu stricto and N.farcinica, reviving the name N. farcinica Trevisan 1889. The N. asteroides in the new sense could furthermore be divided into two species, N. asteroides in a newer sense and N. nova sp. nov. (Table 1). The genus Nocardia is differentiated from genera Mycobacterium and Rhodococcus by the characteristics shown in Table 2. The identification of Nocardia species is carried out according to the schedule shown in Table 3.
  • 山岸 文雄, 村木 憲子, 佐藤 展将, 鈴木 公典, 伊藤 隆, 庵原 昭一
    1988 年 63 巻 9 号 p. 611-615
    発行日: 1988/09/15
    公開日: 2011/05/24
    ジャーナル フリー
    Three cases of pulmonary tuberculosis, who mainly complained of hoarseness and were diagnosed as being complicated with laryngeal tuberculosis, were reported.
    In Case 1, the larynx showed granulomatous lesion; its histology revealed the presence of epithelioid cell granuloma with Langhans giant cells.
    In Case2, there was granulomatous lesion with ulceration in larynx.
    In Case3, the mucosa of larynx showed redness, erosion and edema 4 months after the beginning of treatment.
    These3patients were determined to be highly sputum positive cases with Gaffky's number5-7. In fact, Cases2and3caused an epidemic and familial infection, respectively. Although laryngeal tuberculosis has decreased in number, it was thought that this disease could as yet not be excluded from a group of diseases for differential diagnosis, as its clinical symptoms and findings are similar to those of laryngeal cancer.
  • 藤野 忠彦, 田野崎 隆二, 本間 敏明, 渡辺 定友, 村松 信彦
    1988 年 63 巻 9 号 p. 617-623
    発行日: 1988/09/15
    公開日: 2011/05/24
    ジャーナル フリー
    The patient, a 63 year old female, was admitted to a nearby hospital with acute fever and severe cough.Her chest X-ray showed a solid shadow, indicating a foreign body in the right intermedius bronchus and a pneumonia shadow in the right lower lung field (Fig.1). The foreign body-which was proven to be her denture bridge-was removed, and the fever subsided.The patient has been ill and unconcious for 10 years following meningitis and cerebral atrophy.Therefore it is not known when the denture bridge was swallowed into the bronchus.But it is thought that the foreign body had been lodged there for at least 4 years.After removal of the foreign body, the pneumonia shadow on the chest X-ray film was much improved, but sputum examination showed frequent expectoration of acid-fast bacilli.The acid-fast bacilli were identified as Mycobacterium scrofulaceum using the Atypical Mycobacterium Identification Kit (Kyokuto, Co., Tokyo, Japan) as shown in Table 3.Anti-tuberculous agents including SM, INH, and RFP, were administered.
    The patient had no history of previous tuberculous infection.The chest X-ray films showed no abnormal foci indicative of tuberculosis.The tomogram showed bronchiectatic changes in the right lower bronchus (Fig.3). In this case, it is suspected that 1) a foreign body-the denture bridge-caused bronchiectasis of the right lower bronchus and then 2) atypical mycobacterial infection ocurred at this spot.Pulmonary. Mycobacterium scrofulaceum infection is rare (0.7% of total atypical mycobacterial infections) in Japan.
  • 厚生省保健医療局結核難病感染症課編
    1988 年 63 巻 9 号 p. 627-628
    発行日: 1988/09/15
    公開日: 2011/05/24
    ジャーナル フリー
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