Kekkaku(Tuberculosis)
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
Volume 64, Issue 10
Displaying 1-6 of 6 articles from this issue
  • Michio TSUKAMURA
    1989 Volume 64 Issue 10 Pages 595-598
    Published: October 15, 1989
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    The morphology of mycobacteria is usually examined by taking a sample from colonies already developed on the medium surface. By this method, Mycobacterium avium complex is considered to form short rods or a little longer rods and occasionally some filaments. We inoculated test strains on Ogawa egg medium slants by a loop and incubated at 37°C. After incubation for 2, 3 and 4 days, unvisible or only scarecely visible growth was taken by loop and placed on slides. The samples were stained by the Ziehl-Neelsen method and observed microscopically. Of 50 strains of M. avium complex examined, 4 strains showed mycelia after incubation for 3 days. These mycelia were not observed after incubation for 7 days when visible colonies developed but only rods were observed. Other 46 strains did not show mycelium but showed filamentous growth after 3 days. The change observed was very similar to morphological change of nocardiae which first formed mycelia and thereafter the mycelia were divided into rods. In other slowly growing mycobacteria, M. tuberculosis, M. bovis, M. kansasii, M. scrofulaceum, M. gordonae, M. marinum and M. nonchromogenicum, such mycelium formation was not observed. The mycelium or filament formation in early stage of the growth seemed to be specific for M. avium complex together with M. xenopi.
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  • Fumio YAMAGISHI, Noriko MURAKI, Kiminori SUZUKI, Takashi ITOH, Aya HAY ...
    1989 Volume 64 Issue 10 Pages 599-604
    Published: October 15, 1989
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    1) Two students of different high-schools were found to have pulmonary tuberculosis by school medical examination. These two students learned in the same private extra-school tutoring institute when they were junior high-school students. Assuming this event as a group infection of tuberculosis in the extra-school tutoring institute, we performed an extraordinary examination on the teachers working there.
    2) In the extraordinary examination, a patient who could be judged as the source of infection was found.
    3) As a result of extraordinary examination on students learning in the institute, a bimodal distribution was noted in the size of tuberculintest, and compared with the results of tuberculin test at the first grade of junior high-school, the reaction was amplified. Twenty four students were subjected to chemoprophylaxis.
    4) One case of pleurisy occurred from a student recommended chemoprophylaxis by the ad hoc committee on epidemic of tuberculosis, and the recommendation was neglected by an attending physician.
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  • Part I: Factors Relating to the Onset of Tuberculosis in Three Health Centers of Tochigi Prefecture
    Masayo KOBAYASHI
    1989 Volume 64 Issue 10 Pages 605-612
    Published: October 15, 1989
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    While the incidence rate of tuberculosis had steadily decreased in Tochigi Prefecture until 1981, the rate began to increase since around 1982 in contrast to the continuous decrease in Japan.
    An interview survey of the factors and the background of newly registered tuberculosis patients in three health centers of Tochigi Prefecture was coducted to clarify the reason of the recent undesirable changes of the epidemiological picture of tuberculosis in Tochigi Prefecture. Those items included in the interview survey were X-ray and bacteriological findings at registry, mode of detection, previous history of tuberculosis, symptoms, coverage of previous examination, etc.
    Of 178 newly registered tuberculous patients in these three health center districts in Tochigi Prefecture, 175 (98%) were interviewed by public health nurses during the period from April, 1987 to January, 1988.
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  • Yasuko UEDA, Kiyo FUJITA, Kohta KOHNO, Kazuhiro ICHINOSE, Hiromichi FU ...
    1989 Volume 64 Issue 10 Pages 613-619
    Published: October 15, 1989
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    A case of isoniazid (INH)-induced lupus occurring in a 62-year-old man is presented. He visited our hospital in May 1986 and a cavitary lesion was found in the right upper lobe on a chest roentgenogram. He had no previous history of treatment with antituberculotic agents. Though acid-fast bacilli were not found in his sputum, pulmonary tuberculosis was strongly suspected and INH, rifampicin and ethanbutol were administered. Four days after starting the treatment, minimal left pleural effusion was seen on chest X-ray film. Three months later he began to complain polyarthralgia in his digital joints. In a pleural effusion many lymphocytes were found; and the antinuclear antibody (ANA), the antiextractable nuclear antigens (ENA) antibody, and the RNase resistant anti-ENA antibody were positive, and their titres were 20×, 1000× and 1000×, respectively, and the immune complex (IC) was 16.0μg/ml (LT 5). In blood serum, the ANA test the and-ENA antibody and the RNase resistant anti-ENA antibody were positive with titres 40×, 640× and 640× respectively;and the IC was 14.0μg/ml, and the RA test was positive. The improvement of clinical findings and disappearance of auto-antibodies seen after stopping INH confirmed the diagnosis as INH-induced lupus.
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  • FUTURE DIRECTION OF TREATMENT, UNDERGRADUATE, AND POSTGRADUATE TRAINING OF TUBERCULOSIS
    Masahiko YAMAMOTO
    1989 Volume 64 Issue 10 Pages 621-681
    Published: October 15, 1989
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
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  • [in Japanese]
    1989 Volume 64 Issue 10 Pages 689-690
    Published: October 15, 1989
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
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