結核
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
64 巻, 9 号
選択された号の論文の8件中1~8を表示しています
  • 井村 价雄, 大塚 十九郎, 山本 弘, 小林 利子, 鈴木 光, 中野 裕康, 今橋 正令
    1989 年 64 巻 9 号 p. 545-549
    発行日: 1989/09/15
    公開日: 2011/05/24
    ジャーナル フリー
    In 13 patients undergone reoperation for chronic empyema during 9 years period from 1975 to 1983, the operative technique employed for the initial treatment, number of operations, findings of fistula and residual cavity and complications associated with each technique were reviewed with following results.
    Among these reoperated patients, the initial operation was thoracic cavity reduction in 5 cases, pulmonary detachment in 6 cases and air-plombage (Kinchu method) in 2 cases. Reoperation was carried out in a total of 27 times.There were 6 cases (46%) which were operated more than 3 times.These 6 cases included none of the cases which underwent air plombage.At the time of the first reoperation, fistula was observed in 11 out of 13 cases. At the final operation the residual cavity was accompanied with fistula in 7 cases and empyema in 5 cses.As the final operation, chest wall plombage chiefly by a modification of Grow's method combined with pedicle muscle plombage was employed.In cases indicated for more than two times of operations of thoracic cavity reduction, chest wall plombage was useful for reoperation.
    On the basis of these results, indication of each operation to improve results of surgical treatment of chronic empyema was discussed by taking into consideration advantages and complications of each operative technique.
  • 伊奈 康孝, 佐道 理文, 高田 勝利, 山本 正彦, 荒川 啓基, 野田 正治, 柿原 秀敏, 宮地 厚雄, 森下 宗彦, 吉川 公章
    1989 年 64 巻 9 号 p. 551-556
    発行日: 1989/09/15
    公開日: 2011/05/24
    ジャーナル フリー
    Antigen presenting capacity (APCC) by monocytes (Mono) and alveolar macrophages (AM), using PPD as the antigen, was determined in 15 patients with pulmonary tuberculosis and 9 healthy controls who all showed positive PPD skin tests.
    Results were as follows:
    1) Mono from both healthy controls and tuberculosis showed APCC to autologous peripheral T lymphocytes, and no significant difference was observed between the two groups.
    2) AM from tuberculosis showed APCC to autologous peripheral T lymphocytes, however AM from healthy controls did not.
    3) APCC by autologous Mono or AM to lung T-lymphocytes was lower than that to peripheral T-lymphocytes, but the difference was not significant.
    4) In tuberculosis, APCC, observed before chemotherapy, was remarkably weakened during the first two months of therapy, and almost recovered to the previous level thereafter.
    5) The mechanism which enhances APCC by AM in tuberculosis is uncertain.But neither increased DR antigen expression on AM nor release of IL-1 from AM suggested to be responsible for the enhanced APCC in tuberculosis.
  • 束村 道雄
    1989 年 64 巻 9 号 p. 557-562
    発行日: 1989/09/15
    公開日: 2011/05/24
    ジャーナル フリー
    In vitro susceptibility testing to streptomycin, kanamycin and enviomycin was carried out in nontuberculous mycobacteria and the results were compared with those of M. tuberculosis strains.Among nontuberculous mycobacteria tested, only M.xenopi strains exhibited similar minimal inhibitory concentration (MIC) values to streptomycin with M. tuberculosis strains.On the other hand, M.xenopi, M.malmoense and M.marinum strains showed the same MIC values to kanamycin with the MIC values for M.tuberculosis strains. The MICs of enviomycin for M.kansasii, M.malmoense, M.szulgai, M.xenopi and M. marinum strains were similar to those for M.tuberculosis strains.Out of 64 strains of M.avium complex, the MIC value similar to that for M.tuberculosis strains was shown in 16% of strains to streptomycin, in 42% of strains to kanamycin, and in 50% of strains to enviomycin.
  • 第1報: 運動負荷時の血液ガス分圧測定方法
    吉田 文香
    1989 年 64 巻 9 号 p. 563-577
    発行日: 1989/09/15
    公開日: 2011/05/24
    ジャーナル フリー
    With advances in treatment for tuberculosis, pulmonary tuberculosis has become curable.However, chronic respiratory failure has been more often observed in those who have ever had thoracic operation, and were cured with anti-tuberculous chemotherapy in spite of initially severe pulmonary tuberculosis with wide spread lesions in both lungs, particularly in the aged.Therefore it is now necessary to understand accurately the real physio-dynamic situation of respiro-circuratory impairment in these patients.
    For this purpose, an exercise test was newly designed, and changing curves of blood gas (02-and CO2-partial pressure, measured transcutaneously) were drawn in 4 healthy persons and 23 recovered patients from pulmonary tuberculosis.The newly designed method was carried out by using Treadmill walk apparatus (NIHON-DENKI SANEI Co.Japan), trans cutaneous blood gas measurement apparatus (RADIO-METER Co.Copenhagen) and automatic blood pressure measurement apparatus (KYORIN Co.Japan).Treadmill walk exercise test was done through Bruce-Sheffield coverted method.The details of this exercise test are written and illustrated in this paper.The results of the test were classified into 4 types by the changes of transcutaneously measured 02 partial pressure curve during the test: 1.unchanged, 2.slightly decreased, 3.moderately decreased, 4. markedly decreased.The significance of these 4 types will be discussed in the next report after examining more convalescents from pulmonary tuberculosis.
    The reproducibility of this test was examined in 6 patients, and it was almost good.
    In addition, in 3 out of 27 patients, odd curves contrary to our expectation, that is increase of the value of trans-cutaneously measured 02 partial pressure and/or decrease of the value of trans-cutaneously measured CO2 partial pressure immediately after the initiation of the first test were observed.But in the second test, carried out in the other
  • 横山 繁樹, 谷口 博之, 近藤 康博, 松本 浩平, 岡田 朝生
    1989 年 64 巻 9 号 p. 579-584
    発行日: 1989/09/15
    公開日: 2011/05/24
    ジャーナル フリー
    A 52-year-old man, who had undergone right upper lobectomy because of active tuberculosis 29 years before, was admitted with complaints of severe cough and expectration.Two years ago, he had pulmonary aspergillosis and was successfully treatedwith some anti-mycotic agents.This time his chest X-P showed fungus ball in a residual tuberculous cavity in the right upper field and he was diagnosed as pulmonary aspergilloma from the results of radiological findings, sputum culture, and serologic test. By bronchofiberscopy fungus ball was observed.With transbronchial infusion of Amphotericin B, intravenous administration of Miconazole and oral administration of Flucytosine, clinical symptoms have improved and lysis of fungus ball was observed. Sputum culture revealed Aspergillus flavipes group.Bronchopulmonary aspergillosis, which was incurable by surgical treatment because of underlying disease, was successfully treated with transbronchial infusion of Amphotericin B and administration of some anti-mycotic agents.
  • 永井 定
    1989 年 64 巻 9 号 p. 585-591
    発行日: 1989/09/15
    公開日: 2011/05/24
    ジャーナル フリー
    More than 10 mycobacterial proteins (MPB or MPT) have been isolated from the nutrient fluids after cultivation of Mycobacterium bovis BCG (Japanese substrain) or M.tuberculosis H37Rv on Sauton medium.The genes for 4 antigens, MPB70, MPB64, α-a ntigen (MPB59), and MPB57, were cloned so far and the complete nucleotide and amino acid sequences were determined.MPB 70 is a quite unique protein in 3 points;a highly species-specific antigen for M.bovis, a large amount of secretion more than 10% of the total protein amount in the culture fluid when the cells are actively growing, and a composition with hydrophobic amino acids in a high rate.MPB64 was also a unique antigen specific to M.bovis and M.tuberculosis with a strong reactivity in delayed-type hypersensitivity.MPB59, corresponds to α-antigen, was a protein of a group of several similar configurations and was commonly found in the mycobacterial species.These 3 antigens are synthesized in the cells binding with each signal peptide which is characteristic of secreted proteins.A heat stable protein, MPB57, a dominant component of PPD, corresponded to BCG-a or 10 kD protein and is supposed to be one of the heat shock proteins.
  • 厚生省保健医療局結核・感染症対策室編
    1989 年 64 巻 9 号 p. 593-594
    発行日: 1989/09/15
    公開日: 2011/05/24
    ジャーナル フリー
  • 1989 年 64 巻 9 号 p. e1
    発行日: 1989年
    公開日: 2011/05/24
    ジャーナル フリー
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