結核
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
67 巻, 10 号
選択された号の論文の5件中1~5を表示しています
  • A. A. Hafeiz, H. A. Issa, B. EL-Kammah, M. A. Abdel-Hafez, M. A. Abdou ...
    1992 年 67 巻 10 号 p. 647-652
    発行日: 1992/10/15
    公開日: 2011/05/24
    ジャーナル フリー
    Fifty pulmonary tuberculous patients (minimal moderate and far-advanced), 18 TB-healed persons and 15 healthy control subjects were examined for plasma levels of adrenaline (AD), noradrenaline (NA), dopamine (DA), ACTH and cortisol. The estimated hormones were found to be increased significantly with the severity of the disease suggesting that the stress of infection plays a role in induction of enzymes responsible for catecholamines synthesis with subsequent stimulation of ACTH and cortisol secretion. Noradrenaline appeared the most effective in this respect.
  • 池田 一成, 杉森 光子, 川崎 一輝, 黒川 博, 錐本 忠市
    1992 年 67 巻 10 号 p. 653-658
    発行日: 1992/10/15
    公開日: 2011/05/24
    ジャーナル フリー
    Twelve children who developed active tuberculosis even after receiving isoniazid (INH) chemoprophylaxis were seen at Tokyo Metropolitan Children's Hospital from 1982 through 1991. All cases received INH more than 9mg/kg/day, except for one case in which the amount of INH administered at the referring hospital was unknown and Streptomycin was administered together with INH. The age of starting INH prophylaxis ranged from 2 months to 13 years, and the age at which clinical symptoms and/or laboratory evidences of active tuberculosis were first manifested ranged from 4 months to 18 years. Five patients developed active tuberculosis after the completion of chemoprophylaxis and patients during chemoprophylaxis, with the first presentation ranging from primary complex (seven), chronic pulmonary tuberculosis (two), tuberculous meningitis (two), and tuberculous pleuritis (one). None of the Mycobacterium tuberculosis resistant to INH was isolated.
    Reviewing these patients, eleven cases had at least one of the following factors: (1) age less than two years old (2) infectious sources expectorated more Mycobacterium tuberculosis (3) delay in starting INH. Above factors should be considered in initiating INH chemopro phylaxis and subsequent follow-up of the patients.
  • 乾 健二, 青木 稔, 和田 洋巳, 人見 滋樹
    1992 年 67 巻 10 号 p. 659-662
    発行日: 1992/10/15
    公開日: 2011/05/24
    ジャーナル フリー
    A 64-year-old woman was admitted with the chief complaints of severe back pain. Chest X-ray film on admission showed an abnormal mass lesion in the right upper mediastinum. Chest tomography and chest CT films revealed destruction of thoracic vertebrae (Th 2 and 3) and paravertebral abscess. Chemotherapy containing RFP was started under diagnosis of active tuberculous spondylitis of thoracic vertebrae. Three months later, curative operation for spondylitis were performed. She underwent the resection of necrotic bone and the anterior spinal fusion using transplanted bone autograft. Her post-operative course was good and she discharged three months after curative operation. Tuberculous spondylitis is still important diseases at the differential diagnosis from metastatic vertebral tumors. This report describes a successful case of surgical treatment for tuberculous spondylitis of thoracic vertebrae.
  • 佐藤 勝昌
    1992 年 67 巻 10 号 p. 663-665
    発行日: 1992/10/15
    公開日: 2011/05/24
    ジャーナル フリー
    I compared counting efficacies of CFU-enumerating method for the number of mycobacteria (Mycobacterium intracellulare and M. fortuitum) locating in cultured macrophages with that of microscopic counting method. Zymosan A-induced macrophages from ddY mice were infected with either M. intracellulare or M. fortuitum by incubation in 10% FBS-RPMI 1640 medium containing the organisms for 1 hr, thereafter thoroughly washed to remove extracellular bacilli, and cultured for 3 to 5 days. At intervals, macrophages were thoroughly rinsed and subjected to either CFU-enumeration or microscopic counting, as follows. In the former method, macrohages were lysed with 0.2% Tween 80-distilled water by sonication using Handy Sonic and CFUs were counted on 7H11 agar plates. In the latter method, the number of acid-fast bacilli was counted by microscopy for macrophages after Ziehl-Toda's staining. The number of bacteria by the CFU-enumerating method was much greater than that by the microscopic counting method.
  • 1992 年 67 巻 10 号 p. 667-693
    発行日: 1992/10/15
    公開日: 2011/05/24
    ジャーナル フリー
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