Kekkaku(Tuberculosis)
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
Volume 67, Issue 5
Displaying 1-8 of 8 articles from this issue
  • Abdel Rahman A. Hafiez, Bothaina El-Kamma, Mohamed A. Abdel-Hafez, Ess ...
    1992 Volume 67 Issue 5 Pages 363-367
    Published: May 15, 1992
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    This work was carried out on 150 subjects. They were classified into four groups: group I: Bronchogenic pulmonary T. B. (n=96); group II: Haematogenous T. B. (n=15); group III: Healed T. B. (n=16), group IV: Healthy control (n=23). Insulin tolerance test was done for each subject to assess the hypothalamo-hypophyseal axis. Glucose, ACTH, cortisol, GH, and PRL levels were estimated during fasting and over three hours after insulin administration. In group I and II the patients exhibited higher fasting levels of anti-insulin hormones and they respond greater than normals to insulin-induced hypoglycaemia. This might indicate early affection of the pituitary gland by TB infection, yet insulin-induced hypogly caemia assured efficient function of the gland. In healed TB patients, no significant changes were obtained in the different hormonal behaviour, whether in the fasting state or after stimulation. This might be explained by improvement of the health condition of the patients, and relief of the stress induced by TB infection.
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  • with Modified Conservative Operation
    Tokuro OTSUKA, Yoshio IMURA, Hiroshi YAMAMOTO, Toshiko KOBAYASHI
    1992 Volume 67 Issue 5 Pages 369-376
    Published: May 15, 1992
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    During the past 10 years 26 patients were operated on for pulmonary aspergilloma (20 males and six females, mean age of 55.8 years). Lung resections were peformed on 13 cases (Group 1). Conservative operations were performed on the remaining cases, including one bilateral operation case (Group 2). New paragraph.
    The oparative techniques in Group 1 were: lobectomy 11 cases of lobectomy, one case of partial resection; and one case of segmental resection. The operative techniques for Group 2 were; five cases of thoracoplasty and cavernoplasty; three cases of thoracoplasty plus cavernoplasty and muscle flap; three cases of thoracoplasty and muscle flap; one case of thoracoplasty and air-plombage; and two cases of cavernoplasty. A second operation was required in four and seven cases in Groups 1 and 2, respectively, and a third operation in two and four cases respectively. The conservative technique was used in all of additional operations required.
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  • Yuka SASAKI, Fumio YAMAGISHI, Kiminori SUZUKI, Noriko MORI, Takenori Y ...
    1992 Volume 67 Issue 5 Pages 377-381
    Published: May 15, 1992
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    A clinical study of 23 patients with Mycobacterium kansasii infection of the lung encountered at National Chiba Higashi Hospital from 1988 to 1990 was carried out. All 23 cases were male, aged from 25 to 81 years-old. Diagnoses were confirmed by sputum culture. The cases consisted of 15 primary infections and 8 secondary infections. Out of the 23 cases, 11 were detected by mass screening with chest X-ray findings, 10 cases were discovered when visiting the hospital because of chest complications and two cases were diagnosed during the observation of other diseases. On admission, sputum smear examintions were positive for 15 patients and negative for 8 patients. Chest X-ray findings using the roentgenological classification criterion for pulmonary tuberculosis established by the Japanese Society for Tuberculosis, 20 cases revealed a Type II shadow and three cases revealed a Type III shadow. One patient has died from another disease, two are undergoing chemotherapy, two have ceased chemotherapy treatment, and 18 patients have completed the treatment, Sputum cultures rapidly turned to negative for mycobacterium detection after chemotherapy treatment. The prognosis is considered to be quite good.
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  • Hiroyuki NOZAKI, Takeo TOYODA, Shutaro TAKASHIMA, Tetuya URANO, Kazuko ...
    1992 Volume 67 Issue 5 Pages 383-392
    Published: May 15, 1992
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    We have experienced 6 cases of intracranial tuberculosis since 1985. 2 cases were diagnosed as intracranial tuberculoma without tuberculous meningitis, and 4 cases were diagnosed as tuberculous meningitis. Brain CT showed intracranial tuberculomas in three of them, and showed cerebral infarcts in two cases, and showed hydrocephalus in two cases. Brain CT on intracranial tuberculosis showed various findings.
    In two cases with tuberculous meningitis, brain CT showed many tuberculomas with ringed or nodular enhancement appeared after adequate chemotherapy had been started. About 1 year later, a few tuberculomas were found with homogeneous enhancement and were enlarged while the chemotherapy was continued. But later they were reduced in size.
    The above facts may suggest that intracranial tuberculoma could appear and be enlarged on cranial CT in spite of adequate anti-tuberculous chemotherapy during a course of tuberculous meningitis. They also suggest that the continuation of adequate chemotherapy might be necessary to the treatment of intracranial tuberculomas.
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  • Masako WADA
    1992 Volume 67 Issue 5 Pages 393-407
    Published: May 15, 1992
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    Flow cytometric analysis was carried out on peripheral blood cells from patients with tuberculosis (TB) (n=84) and with mycobacteriosis other than tuberculosis (MOTT) (n=38). A whole blood-staining-hemolysis procedure was used for the preparation of samples being analyzed, and the cells were double-stained with various combinations of fluorescein isothiocyanate (FITC)-and phycoerythrin (PE)-labeled monoclonal antibodies. These procedures enabled us to obtain quite reproducible results. As patients of more than 70 years old showed apparently distinct T lymphocyte profiles compared with those less than 70 years of age, this investigation was carried out only on patients of less than 70 years old.
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  • Tadaaki SAKAI, Takaaki IKEDA, Yoshihiro NISHIMURA, Hirohisa HORINOUCHI ...
    1992 Volume 67 Issue 5 Pages 409-412
    Published: May 15, 1992
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    A 79-year-old housewife complaining of shortness of breath presented with a LUL mass lesion on chest roentgenogram. Bronchofiberscopic biopsy and curettage revealed adenocarcinoma as well as acid-fast bacilli of Gaffky-4. Further investigations showed increased ESR, CRP levels and positive RF. PPD skin test was positive measuring 557times;43mm. A left upper lobectomy with mediastinal lymphnode dissection was performed. The mass was in S1+2 and measured 2.7×2.5×1.5cm. Histologically caseaous necroses and spotted granulomas of tuberculosis were surrounded by bronchioloalveolar cell carcinoma. Recent discussion concerning the simultaneous occurrence of pulmonary tuberculosis and bronchogenic carcinoma suggests a higher coexistence of both diseases. However, the coexistence of active tuberculosis with carcinoma in the same region, as in our case, is quite rare and suggests an etiological closer relationship between both diseases.
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  • Yukinori MATSUZAWA, Yoko NAKAMURA, Sawako NAKAGAWA, Keisaku FUJIMOTO, ...
    1992 Volume 67 Issue 5 Pages 413-417
    Published: May 15, 1992
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    A 42-year-old woman was admitted because of cough, sputum, and fever. A chest roentgenogram revealed a nodular density in the left upper lung field with satellite lesions compatible with tuberculoma. Mycobacterium tuberculosis was detected from sputum. Five weeks after starting the treatment with 0.4g/day of isoniazid, 0.45g/day of rifampicin, and 0.75g/day of streptomycin, she showed itching erythema in the trunk. The white blood cell count was 4, 500/mm3 with 14% eosinophils, and serum transaminases were slightly increased (GOT 101U/L, GPT 74U/L). Although isoniazid and rifampicin were stopped, the erythema with exfoliation spread to her extremities, suggesting exfoliative dermatitis. The white blood cell count reached 15, 990/mm3 with 68% eosinophils (10, 810/mm3). Stimulation indices measured with the lymphocyte stimulation test (LST) were 109% with rifampicin, 140% with isoniazid, and 275% with streptomycin, suggesting streptomycin-induced allergy. After cessation of streptomycin, the symptoms gradually improved. After the reaction had subsided, the treatment with isoniazid, rifampicin, and ethambutol was resumed, but she showed no further adverse reactions. LST seems to be very useful to identify the drug or drugs responsible for the reactions occurred during the treatment by antituberculosis drugs.
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  • [in Japanese]
    1992 Volume 67 Issue 5 Pages 421-426
    Published: May 15, 1992
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
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