巻号一覧
69 巻, 11 号
選択された号の論文の7件中1～7を表示しています
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野崎 博之, 福内 靖男, 厚東 篤生, 田中 耕太郎, 小張 昌宏1994 年 69 巻 11 号 p. 663-670
発行日: 1994/11/15
公開日: 2011/05/24
ジャーナル フリーThe level of adenosine deaminase (ADA) activity in the cerebrospinal fluid is used as a supportive diagnostic measure for tuberculous meningitis. However the time-course of adenosine deaminase activity of the cerebrospinal fluid in patients with tuberculous meningitis remains unknown. The present study describes 4 patients with tuberculous meningitis in whom ADA activity in the cerebrospinal fluid was serially determined in order to clarify the effects of anti-tuberculous chemotherapy on ADA activity in the cerebrospinal fluid. In two of these patients the ADA did not show a high activity in the early stage of the disease. But in all cases the ADA showed a high activity after all, and gradually declined and reached the normal level at approximately 1 month after the initiation of chemotherapy. It seems that the decrease in the ADA activity was seen when T cells in the cerebrospinal fluid returned to a static state upon removal of mycobacterial antigen by the treatment. The level of ADA in the cerebrospinal fluid is considered to be one of the useful measures for diagnosis and follow-up in patients with tuberculous meningitis.抄録全体を表示PDF形式でダウンロード (1252K) -
和田 雅子, 吉山 崇, 吉川 正洋, 尾形 英雄, 杉江 琢美, 中園 智昭, 杉田 博宣1994 年 69 巻 11 号 p. 671-680
発行日: 1994/11/15
公開日: 2011/05/24
ジャーナル フリーFrom January 1991 to December 1992, 419 patients with pulmonary tuberculosis were initially treated at Fukujuji Hospital. Among them, 190 patients, who were younger than 80 years old and had pulmonary tuberculosis with cavities or infiltration of extension 2 or 3, and/or were sputum-smear positive, had been treated by 6-month short course regimen containing pyrazinamide, 2HRS (E) Z/4HRE. And were eligible for the evaluation of the clinical usefulness of pyrazinamide-containing regimen for the initial treatment of pulmonary tuberculosis. The dose of pyrazinamide was 1.2g per day irrespective of body weight. The patients of this treatment group consisted of 151 males and 39 females, and mean age of the males was 45.3 and that of the females was 43.8 years old. At the start of the treatment, 74% of the cases were smear positive, 70% were cavitary, and 6 cases each showed primary resistance to isoniazid and to streptomycin, respectively, and only one case showed resistance to both of isoniazid and streptomycin. There was no primary resistant case to either rifampicin or ethambutol.抄録全体を表示PDF形式でダウンロード (1209K) -
浜本 康平, 小山 弘, 橋平 誠, 谷口 隆, 橋本 圭司, 大迫 努1994 年 69 巻 11 号 p. 681-687
発行日: 1994/11/15
公開日: 2011/05/24
ジャーナル フリーWe analyzed retrospectively the clinical data of 9 patients with miliary tuberculosis who had been treated in Kyoto City Hospital during the past 12 years. Majority of our patients were female (7 of 9) and were of elder age-groups (mean age: 68.5 years, range: 56-85 years). The most common symptoms at the first visit were fever, fatigue and loss of appetite, but respiratory symptoms were rather rare and moderate. Some cases showed normal chest radiograms at the onset, but during the course of the disease miliary shadows were noticed in all cases. Tuberculin test and smear examination of sputum were not diagnostic.
In 4 cases, fiberoptic bronchoscopy had been performed together with bronchoalveolar lavage (BAL), bronchial washing and transbronchial lung biopsy (TBLB). Smear examina tion of BAL-fluid or bronchial washing for acid-fast bacilli was positive in all 4 cases tested.抄録全体を表示PDF形式でダウンロード (5373K) -
鬼塚 徹, 河野 昌也, 麻生 真佐1994 年 69 巻 11 号 p. 689-692
発行日: 1994/11/15
公開日: 2011/05/24
ジャーナル フリーTuberculous involvement of the anus is very rare at present as the result of BCG-Vaccination and improvement of public health.
We report a juvenile case of tuberculous anal fistulae complicated to pulmonary tuberculosis. A 22-year-old male was admitted with symptoms of 13 month- history of intermittent anal pain, low grade fever and cough. Chest X-ray showed bilateral middlezone infiltrates with cavitation. Perianal inspection revealed a large ulcer with purulent exudate and a few fistulae. Sputum smears showed acidfast bacilli. A biopsied specimen of perianal fistulae showed granulomatous lesions with central necrosis, epitheloid cells and multi-nucleated giant cells. With three-drug antituberculous regimen, his symptoms resolved, radiographic infiltrates improved, and the perianal fistulae were cured.
It was speculated that the tuberculous anal fistulae in this case were caused by the dissemination from the pulmonary focus via the hematogeneous and lymphogeneous routes, because any tuberculous lesion was not detected in the gastrointestinal tract and rectum.抄録全体を表示PDF形式でダウンロード (2442K) -
本邦におけるHIV感染肺結核症5例の検討小山 隆三, 中西 文男, 加藤 誠也1994 年 69 巻 11 号 p. 693-698
発行日: 1994/11/15
公開日: 2011/05/24
ジャーナル フリーRecently we encountered a case of pulmonary tuberculosis with HIV infection. The patient was 54-years old male. His chief complaints were anemia, emaciation and severe diarrhea. He was admitted to our hospital on September 18, 1992. He had been diagnosed in another clinic as having pulmonary tuberculosis before the admission to our hospital. His chest films taken on admission revealed homogeneous infiltrates with cavitation in right upper lobe. Serial chest X-rays consisted with the findings of post-primary tuberculosis. Sputum smear for acid fast bacilli was positive. From his clinical manifestations and lifehistory, we had a suspicion that he had infected with HIV.
Laboratory findings were as follows: serum albumin level was 1.9 g/dl, CRP was 10.2mg/dl, serological tests for HIV were positive by ETA, IFA and western blott method, totallymphocyte count was 819/40, CD4+ T lymphocyte count was 120/g/CD4±/CD8+ ratio was 0.2.
He was treated with AZT, isoniazid, streptomycin and rifampicin. The disease progressed rapidly and interstitial pneumonia, jaundice and clouding of consciousness appeared at the terminal stage. He expired on October 14, 1992. In this paper, the authors reported a case of pulmonary tuberculosis with HIV infection and also reviewed 5 cases of pulmonary tuberculosis associated with HIV in Japan.抄録全体を表示PDF形式でダウンロード (1767K) -
大泉 耕太郎1994 年 69 巻 11 号 p. 699-738
発行日: 1994/11/15
公開日: 2011/05/24
ジャーナル フリーPDF形式でダウンロード (4973K) -
厚生省保健医療局エイズ結核感染症課編1994 年 69 巻 11 号 p. 739-741
発行日: 1994/11/15
公開日: 2011/05/24
ジャーナル フリーPDF形式でダウンロード (317K)
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