結核
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
69 巻, 9 号
選択された号の論文の7件中1~7を表示しています
  • 宍戸 真司, 森 亨, 河合 道
    1994 年 69 巻 9 号 p. 543-547
    発行日: 1994/09/15
    公開日: 2011/05/24
    ジャーナル フリー
    The high incidence of tuberculosis among necropsy workers is well known and several problems related to their working conditions have been pointed out. We investigated the possibility of infection with tubercle bacilli under necropsy working conditions using guinea pigs housed in a necropsy room in which about 2, 000 necropsies per year were carried out. Tuberculosis infection developed in one out of five guinea pigs. In addition, we exposed five guinea pigs to tubercle bacilli and sacrificed them in a safety cabinet. The lungs, livers, and spleens were resected, flattened, and sliced finely on a cutting board. Detection of tubercle bacilli from filtered air and the surfaces of the room was attempted, however, no bacilli were cultured. The resected tuberculous lungs were intra-tracheally treated with formalin or physiological saline and the viability of the bacilli in the lung was assessed. Bacilli survived up to two hours after physiological saline injection but no viable organisms were detected after 15 minutes of formalin treatment.
    These findings indicate that the necropsy room workers were exposed to tuberculosis infection. As a preventive control measure, we reccommend to treat tuberculous organs in the safety cabinet and to slice lungs after formalin treatment.
  • 宍戸 真司, 森 亨, 徳留 修身, 河合 道
    1994 年 69 巻 9 号 p. 549-553
    発行日: 1994/09/15
    公開日: 2011/05/24
    ジャーナル フリー
    We examined the incidence of tuberculosis among necropsy staff and the environment in the necropsy rooms at five medical institutions carrying out a large number of necropsy annually in the metropolis of Tokyo. The following results were obtained: 1) Incidence of tuberculosis was high among necropsy workers. 2) The method of wearing face masks was inadequate, 3) Tubercle bacilli were detected from the necropsy workers' aprons and the air-conditioning equipment of the necropsy room. 4) Formalin treatment of resected organs, especially the lungs, was inadequate. 5) The air conditioners in necropsy rooms were not effective.
    Considering these findings, improvement of the working conditions and environment of the necropsy rooms is needed.
  • 前崎 繁文, 増本 英男, 荒木 潤, 浅井 貞宏
    1994 年 69 巻 9 号 p. 555-558
    発行日: 1994/09/15
    公開日: 2011/05/24
    ジャーナル フリー
    The pathohistological findings of transbronchial lung biopsy (TBLB) were compared between Mycobacterium tuberculosis infection (group A) and Mycobacteria other than Mycobacterium tuberculosis (MOTT) infections (group B). The number of positive pathological findings in TBLB were 14 (70 %) in group A and 2 (16 %) in group B, respectively. Eleven cases (55 %) in group A were positive for acid-fast bacilli in TBLB by Ziehl-eelsen stain, and 3 cases of group A showed granulomatous lesion in TBLB. In pathohistological findings of group B, 2 cases (16 %) were granulomatous lesion, 4 cases (33 %) were fibrosis, and 3 cases (25 %) were inflamatroy changes. The pathohistological examination of TBLB was more useful for the diagnosis of pulmonary tuberculosis than for MOTT infection.
  • SM週2日法の是非をめぐって
    豊田 恵美子, 鈴木 恒雄, 田川 渓子, 高原 誠, 伊藤 通成, 荒井 他嘉司, 可部 順三郎, 馬場 治賢
    1994 年 69 巻 9 号 p. 559-563
    発行日: 1994/09/15
    公開日: 2011/05/24
    ジャーナル フリー
    For the purpose to compare the effectiveness of SM and EB as a third drug in the standard regimens and to know whether the addition of SM twice weekly to INH and RFP could be acceptable for the treatment of pulmonary tuberculosis, the efficacy, adverse effects and results of long-term follow-up of the groups consisting of 105 patients treated with SM twice weekly for 6 months in addition to INH and RFP for 9 months (S2 group) and 107 patients treated with EB for 6 months in addition to INH and RFP for 9 months (E group) were observed. The speed of negative conversion of sputum and that of X-ray findings improvement were slightly faster in S2 group than E group but the difference was statistically not signifficant. The incidence of adverse effects such as elevation of serum transaminase values, gastrointestinal troubles, drug allergy and others was not similar in two groups. The relapse was observed in 2 cases of S2 group and 5 cases of E group.
    We concluded that SM twice weekly to INH and RFP is similarly effective as EB in combination with INH and RFP, and the this regimen could be used as standard regimen for pulmonary tuberculosis.
  • 中園 智昭, 尾形 英雄, 水谷 清二, 木野 智慧光
    1994 年 69 巻 9 号 p. 565-569
    発行日: 1994/09/15
    公開日: 2011/05/24
    ジャーナル フリー
    Hilar lymph node tuberculosis with atelectasis of the left upper division in a 23 year-old woman was reported. After 3 months' antituberculous chemotherapy, atelectasis on her chest X ray disappeared completely. The case was considered as so-called epituberculosis. Bronchoscopy revealed the improvement of bronchial obstruction due to hilar lymph node tuberculosis. As the majority of epituberculosis cases were found in infants with soft and elastic bronchi, such an adult case like ours was considered to be rare.
  • 山本 三郎, 大森 正子
    1994 年 69 巻 9 号 p. 571-579
    発行日: 1994/09/15
    公開日: 2011/05/24
    ジャーナル フリー
  • 1994 年 69 巻 9 号 p. 583-585
    発行日: 1994/09/15
    公開日: 2011/05/24
    ジャーナル フリー
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