結核
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
70 巻, 11 号
選択された号の論文の5件中1~5を表示しています
  • 大矢 聡, 竹本 淳紀, 保坂 公徳, 工藤 豊, 荒川 正昭
    1995 年 70 巻 11 号 p. 615-619
    発行日: 1995/11/15
    公開日: 2011/05/24
    ジャーナル フリー
    We measured the in vitro antimicrobial activity of a new quinolone, levofloxacin (LVFX) against seven clinically isolated species of atypical mycobacteria, including 30 strains of M. avium complex. 8 of M. fortuitum, 4 of M. scrofulaceum, 2 of M. kansasii, 2 of M. gordonae, and 1 of M. chelonae (subsp chelonae). LVFX showed a potent antimicrobial activity against M. kansasii, M. gordonae and M. chelonae (subsp chelonae). In addition, it was suggested that LVFX may be effective for the treatment of infections caused by M. avium complex, since satisfactory antimicrobial activity was displayed against some strains of M. avium complex.
    Considering the fact that LVFX shows good concentration levers in sputum, this drug could be used in the chemotherapy against the infection with M. avium complex.
  • 倉澤 卓也, 池田 宣昭, 佐藤 敦夫, 中谷 光一, 松下 葉子, 井上 哲郎, 坂谷 光則, 小林 知加子, 駿田 直俊, 金井 廣一, ...
    1995 年 70 巻 11 号 p. 621-628
    発行日: 1995/11/15
    公開日: 2011/05/24
    ジャーナル フリー
    We studied the clinical features of sixty-one patients with non-tuberculous pulmonary mycobacteriosis (NTM), who were newly diagnosed at five national hospitals in Kinki area during 1993.
    The study subjects were composed of 31 patients with M. avium complex (MAC) disease (20 males and 15 females), 21 with M. kansasii (MK) disease (19 males and 3 females), 2 males with M. szulgai (MS) disease and 2 females with M. chelonae (MC) disease.
    The rate of NTM to all culture proven mycobacteriosis was 20.2% and the rate of NTM to all culture proven, newly discovered mycobacteriosis was 18.2% and the rates were higher than Sakatani's report in 1994 (14.0% in 1991). The ratio of MK to MAC was 22: 35, and the ratio of MK was higher than the report of Sakatani.
  • 小林 義隆, 高野 智子, 平山 典保, 佐藤 信英, 下出 久雄
    1995 年 70 巻 11 号 p. 629-634
    発行日: 1995/11/15
    公開日: 2011/05/24
    ジャーナル フリー
    We conducted a survey on nontuberculous mycobacteria (NTM) isolated in association with colonoscopy at two hospitals.
    NTM was isolated from the fluid-phase of colonic contents in 17.6% of the specimens obtained at hospital A and in 46.3% at hospital B. The rate of isolation from the preexamination suction fluid was 9.5% and 43.3% at hospital A and B, respectively. Tap water samples from both hospitals were examined and proved to be free from contamination with NTM. The mycobacterial species isolated at hospital A were M. chelonae subsp. abscessus, M. chelonae subsp. chelonae, M. fortuitum, and M. gordonae. M. chelonae subsp. abscessus was the only mycobacterial species isolated at hospital B. M. avium complex was not isolated at either hospital. By an additional procedure to cleans and decontamitate the endoscopes by suction with Maskin ethanol solution, the incidence of isolation of NTM from the fluid-phase of colonic contents was significantly reduced. None of the patients from whom NTM was isolated exhibited positive signs of colonic NTM infection by the endoscopic examination and none had anyunderlying diseases which might induce immune suppresion. We suspect that most of the NTM isolates have originated from the contaminated endoscope. In conclusion, when a colonoscopic examination is carried out in suspicion of NTM disease in intestine, it is essential to reassess the possibility of mycobacterial contamination of the colonoscopes and implement appropriate steps for cleansing and sterilization of them.
  • I. ヒト結核の感染・発病と免疫
    露口 泉夫, 冨岡 治明
    1995 年 70 巻 11 号 p. 635-663
    発行日: 1995/11/15
    公開日: 2011/05/24
    ジャーナル フリー
  • 厚生省保健医療局エイズ結核感染症課編
    1995 年 70 巻 11 号 p. 669-671
    発行日: 1995/11/15
    公開日: 2011/05/24
    ジャーナル フリー
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