結核
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
71 巻, 7 号
選択された号の論文の3件中1~3を表示しています
  • 佐々木 結花, 山岸 文雄, 鈴木 公典, 斉藤 正佳, 泉崎 雅彦, 小泉 健一
    1996 年 71 巻 7 号 p. 427-430
    発行日: 1996/07/15
    公開日: 2011/05/24
    ジャーナル フリー
    Forty three patients detected by symptomatic visit and died of active pulmonary tuberculosis were investigated on their social background factors. As to age of 43 cases, 17 cases (40%) were fortieth of fiftieth; namely in young productive age. Sixteen were male and 13 cases lived alone and thirteen cases had no regular occupation when they were admitted. Three were too serious to talk about their case histories. Among other 13 cases, none visited a hospital within three months from the appearance of their symptoms and 8 cases visited a hospital after six months or long from the appearance of their symptoms. Thus, the patient's delay was obvious, and this was actually the cause of death in this cases.
  • 今泉 忠芳
    1996 年 71 巻 7 号 p. 431-434
    発行日: 1996/07/15
    公開日: 2011/05/24
    ジャーナル フリー
    Immunosuppressive acid protein (IAP) was measured in 28 cases with active lung tuberculosis, 24 cases with old lung tuberculosis, and 20 controls.
    IAP elevated in active lung tuberculosis, but not in old lung tuberculosis and the control.
    Elevated IAP in active tuberculosis fell down gradually with the clinical improvement of the disease. IAP seems to be better than erythrocyte sediment rate (ESR) in evaluations the activity of the disease, as it is more sensitive than ESR.
    It is suggested that IAP is an exallent marker to guess the clinical activity of lung tuberculosis.
  • 斧原 康人, 友田 恒一, 仲谷 宗裕, 吉川 雅則, 塚口 勝彦, 徳山 猛, 夫 彰啓, 福岡 和也, 山本 智生, 米田 尚弘, 成田 ...
    1996 年 71 巻 7 号 p. 435-438
    発行日: 1996/07/15
    公開日: 2011/05/24
    ジャーナル フリー
    It is assumed that soluble tumor necrosis factor receptor I and II (sTNF-R I, II) play important roles in the regulation of tumor necrosis factor alpha (TNF-α) activity.
    We measured the levels of circulating sTNF-R in patients with active pulmonary tuberculosis (n=31) and the correlation between TNF-α and sTNF-R in serum level was investigeted. We also compared sTNF-R levels before and after the treatment in 7 cases.
    Significant increase of circulating sTNF-R were found in patients with tuberculosis compared with the normal controls (n=28) (p<0.01). Moreover, significnt positive correlations were found between TNF-α and sTNF-RI and II (r=0.520, r=0.553) in serum comparing sTNF-R levels before and after the treatment for patients with tuberculosis, significant fall was found in sTNF-R I, but not in sTNF-R II.
    As a result, it is suggested that sTNF-R regulates TNF-α activity in patients with tuberculosis, and that sTNF-R I levels could be used as one of the indices to evaluate the clinical activity of tuberculosis.
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