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Volume 73, Issue 1
Displaying 1-5 of 5 articles from this issue
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Shuichi YANO, Shinji SHISHIDO, Takeaki TORITANI, Katsuhiko YOSHIDA, Hi ...1998 Volume 73 Issue 1 Pages 1-3
Published: January 15, 1998
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSWe evaluated the diagnostic value of thoracoscopic examinations in eleven patients whohad pleural effusion and were diagnosed as tuberculous pleurisy. The characteristic whiteor yellowish-white micronodules were observed by thoracoscopy in eight patients and alltheir biopsied tissue were compatible with tuberculosis. We had some cases which werenot determined as tuberculous pleurisy from bacteriological examinations and were determinedonly from the thoracoscopic findings.View full abstractDownload PDF (492K) -
Jun-ichi FUKUI1998 Volume 73 Issue 1 Pages 5-12
Published: January 15, 1998
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSMycobacterium avium-intracellulare complex (MAC) consists of 28 serotypes. Co-infectionof several specific serotype strains with the advent of acquired immunodeficiencysyndrome (AIDS) has been dramatically increasing in the past fifteen years, although thereason for this fact is not clearly understood. Since the cell surface lipid components of MAC impaired the capacity of human peripheral blood mononuclear cells (PBMC) to proliferate, some particular glycopeptidolipid (GPL) with serologically specific carbohydratechains are supposed to inhibit blastogenesis and to affect the immune response in MACinfection. In this study, we have investigated the effect of serovar 4 and 16GPLs on thehuman PBMC function and cell mediated immunity. As the result, it was demonstratedthat the percentage of viable cells was decreased prominently after the incubation of PBMC with the serovar 4 GPL. Blastogenic responses of PBMC to stimulation with thepurified protein derivatives (PPD) were inhibited by the presence of GPL dosedependently.In the case of stimulation with anti-CD3 antibody (a-CD3 Ab), blastogenicresponse of PBMC was suppressed markedly by GPL at the concentration of 175μg/ml. Flow-cytometric analysis demonstrated that the expression of interleukin-2 receptor alphaon a-CD3 Ab-stimulated T lymphocyte was markedly inhibited in the presence of GPL. Enzyme-linked immunosorbent assay showed that the production of interleukin-2 by a-CD3 Ab-stimulated PBMC was reduced dose-dependently after the incubation of PBMC with GPL. In these results, there was no remarkable difference between serovar 4 andserovar 16 GPLs. These results indicate that serovar 4 and 16 GPLs inhibit the cell mediatedimmunity and serovar 4 GPL can affect the viability of PBMC.View full abstractDownload PDF (1266K) -
Tadayoshi IMAIZUMI1998 Volume 73 Issue 1 Pages 13-15
Published: January 15, 1998
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSRemnant like particle (RLP) is a lipoprotein produced by decomposition ofchylomicron or very low density lipoprotein (VLDL). PLP was observed on serum ofcases with active pulmonary tuberculosis.
Serum level of RLP was decreased in all of the patients with pulmonary tuberculosisbelow 2.5mg/dl till 0mg/dl. The level was gradually elevated with clinical improvementof the disease.
It was suggested that denutrition of chronic infection would be reflected to serum RLPlevel in active tuberculosisView full abstractDownload PDF (294K) -
Masahiko YAMAMOTO, Mitsuo ASAKAWA1998 Volume 73 Issue 1 Pages 17-42
Published: January 15, 1998
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSDownload PDF (4200K) -
[in Japanese]1998 Volume 73 Issue 1 Pages 43-45
Published: January 15, 1998
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSDownload PDF (379K)
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