Kekkaku(Tuberculosis)
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
Volume 74, Issue 12
Displaying 1-5 of 5 articles from this issue
  • Yutaka ITOU, Yoshirou MOCHIZUKI, Yasuharu NAKAHARA, Tetsuji KAWAMURA, ...
    1999 Volume 74 Issue 12 Pages 843-847
    Published: December 15, 1999
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    We reviewed the chest CT findings of 15 patients with “primary infection of Mycobacterium avium complex”. All of them were female and the average age of them was 64.9 years old. They received no or only insufficient therapy. Comparing the chest CT findings followed up for the average of 60.9 months interval, only three patients showed clear progression. All of the cases with less than three lobes involved at the onset unchanged or improved. On the radiographic features at the onset, small nodulousor infiltrative shadows were seen in all patients, and bronchiectasis in three patients. Cavity was not seen. The lesions of 12 patients were located in the right upper lobe, 13 patients in the right middle lobe and 14 patients in the left lingula. Mild and limited cases may have potential with no or very slow progression, and case by case selective treatment should be considered.
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  • Yuka SASAKI, Fumio YAMAGISHI, Takenori YAGI, Fuminobu KURODA, Hideki Y ...
    1999 Volume 74 Issue 12 Pages 849-854
    Published: December 15, 1999
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    We experienced an outbreak of tuberculosis among young adults in close contact. The index case (case 1) was 22-year-old builder and was symptomatic for 9 months before diagnosis as pulmonary tuberculosis (PTB). His sputum smear was positive for tubercle bacilli. On immediate family contacts examination carried out at our hospital, his brother and sister (case 3, case 4) were detected as having PTB. His mother (case 5) and father (case 6) were later detected as having PTB by their symptomatic visits after some months, as tuberculin test as not done at first examination.
    Case 7 was 19-yearold-man, and was undiagnosed for 5 months. His sputum smear was positive. Immediately, contacts examination for case 7 as carried out at our hospital, and his colleague (case 8) was detected as having PTB. By interview with the case 7, it was found that the case 1 and the case 7 were close friends and spent long time together.
    Case 10 was 30-year-old builder, and he was accidentally referred to our hospital and was diagnosed as PTB. By the interview with the case 10, it was found that the case 1 and case 10 were members of builders group. This fact was informed to the F health center, and contacts examination for other members of the group were carried out by the F health center, and two young men were detected as having PTB. Analysis of restriction fragment length polymorphism (RFLP) showed that the case 1, the case 5, the case 7, and the case 10 were caused by the same strain of M. tuberculosis. Based on these findings, it is highly suspected that this outbreak was origined from the case 1, and 13 developed tuberculosis and 13 were primarily infected among contacts.
    The characteristics of this outbreak was that the family and contacts examination were enforced and most of the cases were detected at our hospital. If the outbreak of tuberculosis highly suspected, physicians should actively cooperate with health centers for contacts examination.
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  • Masayo KOBAYASHI
    1999 Volume 74 Issue 12 Pages 855-861
    Published: December 15, 1999
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    The purpose of the study is to clarify chronological changes and the regional difference of the incidence of tuberculosis in Tochigi Prefecture. The difference between the first period (1980-1984) and the second period (1990-1994) was analyzed.
    The results are as follows;
    1. The decrease of incidence in the age groups of 20-29 years and over 70 years slowed down in all types of tuberculosis and infectious pulmonary tuberculosis.
    2. The incidence of tuberculosis in the southern part of Tochigi Prefecture was higher than in the other parts, and this could be explained by the fact that the people in the southern part were exposed heavier to tuberculosis infection in the past than the people in other parts.
    3. In the public health center areas where the incidence rate of tuberculosis was high, the slow decline or even increase of the incidence rate among age groups less than 30 years and over 70 years of age was observed and this seemed to affect the higher incidence in these areas.
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  • Tomoyo NARITA, Yoko NAGATA, Kazuko UEMA
    1999 Volume 74 Issue 12 Pages 863-868
    Published: December 15, 1999
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    We experienced an outbreak of tuberculosis in a salesmen's office during the period from 1993 to 1997. The outbreak was detected retrospectively. In July, 1997, a 47-year-old man was diagnosed as pulmonary tuberculosis. As he worked with a 42-year-old man who was already registered in our health center, we suspected an outbreak and started asurvey. Contact examinations were carried out for 9 employees of his office and 3 members of his friends. As the result of these examinations, one employee showed strongly positive tuberculin skin test, and was indicated isoniazid chemoprophylaxis. Furthermore, some contacts told us that seven cases of active tuberculosis and three cases of primary infection indicated chemoprophylaxis had occurred among employees and their family members. The index case was a 41-year-old man who was diagnosed as tuberculosis in January, 1993. The second case among employees had previous history of pulmonary tuberculosis.
    Almost the patients among the employees had a hard life suffering from debts, and had heavy alcohol use. These facts may partly explain the spread of tuberculosis in this office.
    As each case was registered at different health centers, we hadn't noticed the outbreak for 4 years. But it is true that insufficient approach of health centers to contacts caused a serious delay of detecting the outbreak. A thorough investigation for contacts and complete contact examinations are needed.
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  • 1999 Volume 74 Issue 12 Pages 869-905
    Published: December 15, 1999
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
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