The Keio Journal of Medicine
Online ISSN : 1880-1293
Print ISSN : 0022-9717
ISSN-L : 0022-9717
Volume 11, Issue 2
Displaying 1-5 of 5 articles from this issue
  • KIYOMICHI HANABUSA
    1962 Volume 11 Issue 2 Pages 65-67
    Published: 1962
    Released on J-STAGE: March 27, 2009
    JOURNAL FREE ACCESS
    1. The amino acids composing urease were identified by paper chromato-graphy and colour reactions of protein. It was found that urease contains, at least, 16 amino acids.
    2. Among the amino acids found in urease, it was presumed that cystine is present in the smallest quantity and glutamic acid, aspartic acid, and leucine+ isoleucine are in a relatively large amount.
    3. The presence of carbohydrate and phosphorus in this enzyme was not demonstrated.
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  • ICHIRO NAKAYAMA, HISAKICHI MATSUBAYASHI
    1962 Volume 11 Issue 2 Pages 69-81
    Published: 1962
    Released on J-STAGE: March 27, 2009
    JOURNAL FREE ACCESS
    Mice which were infected with Beverley strain of Toxoplasma were examined for distribution and growth of the cysts in central nervous system as well as in eyes.
    1) The cysts were distributed throughout the central nervous system. Among four parts of central nervous system, the cysts were found most abundant-ly in telencephalon and cysts in medulla spinalis were the smallest in number. The largest number of cysts found in telencephalon was 134.52 per mg of the tissue.
    2) Number of cysts in central nervous system increased 1 to 2 weeks after the inoculation and it maintained the same level for several weeks. After 9th week of the infection the cysts began to decrease in number.
    3) Cysts in central nervous system continued to increase in diameter until 15th week of the infection. Cysts in cellebellum were the largest in size among those in 4 parts of the organ. The largest cyst in cellebellum was 107.9μ in diameter.
    4) Presence of the organism in eyes were examined in 34 mice. Cysts were detected directly from eyes in 25 cases and the organism was demonstrated from 5 cases only after subinoculation with the emulsified eyes into clean mice.
    5) The cysts in eyes were found only in the inner surface of retina. Cysts were also found in oculomotor muscles.
    6) Cysts in eyes were generally smaller in number as well as in size compared to those in central nervous system.
    7) No pathological findings were recognized in the tissue of eyes and central nervous system around the cysts.
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  • PRELIMINARY REPORT
    TATSUYUKI KUDO
    1962 Volume 11 Issue 2 Pages 83-85
    Published: 1962
    Released on J-STAGE: March 27, 2009
    JOURNAL FREE ACCESS
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  • HIDEYUKI TOFUKUJI, HIROSHI TAZAKI, TATSUYA HASHIMOTO
    1962 Volume 11 Issue 2 Pages 87-92
    Published: 1962
    Released on J-STAGE: March 27, 2009
    JOURNAL FREE ACCESS
    A case of fused pelvic kidney is reported. The patient was a 55-year-old Japanese male complaining of low back pain for one year.
    Urological examination revealed a fused pelvic kidney which was later confirmed by exploratory laparotomy. Radiological examination, especially the “series renal arteriography” was indispensable for the diagnosis of the case.
    The literature on fused pelvic kidney is reviewed and discussed.
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  • MASAKO MURAOKA, ATSUSHI TAKADA, TAKEO UEDA
    1962 Volume 11 Issue 2 Pages 95-103
    Published: 1962
    Released on J-STAGE: March 27, 2009
    JOURNAL FREE ACCESS
    To find chemotherapeutic agents against the virus, 5-alkyluracils, 5-alkyl-isocytosines and 5-alkyl-6-methylisocytosines were synthesized. By the primary screening test on the type-1 strain of adeno virus, 5-ethyluracil, 5-butyluracil and 5-hexyl-6-methylisocytosine selected. Among the three compounds, 5-hexyl-6-methylisocytosine was effective on the type-1 strain of adeno virus for the secondary screening test, while the other two compounds did not show any effect on the virus. The all tested compounds did not show any inhibitory effect on the poliomyelitis virus and vaccinia virus.
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