The Keio Journal of Medicine
Online ISSN : 1880-1293
Print ISSN : 0022-9717
ISSN-L : 0022-9717
Volume 13, Issue 2
Displaying 1-7 of 7 articles from this issue
  • NOBUKATSU SHIMADA, HIROHARU MATSUDA, TAKEO AMAAKI
    1964 Volume 13 Issue 2 Pages 67-75
    Published: 1964
    Released on J-STAGE: March 27, 2009
    JOURNAL FREE ACCESS
    Download PDF (449K)
  • EIICHI SUGAYA, TADAYOSHI AKIBA, MASAHARU TSUCHIYA, YASUYOSHI KIRYU, MI ...
    1964 Volume 13 Issue 2 Pages 77-85
    Published: 1964
    Released on J-STAGE: March 27, 2009
    JOURNAL FREE ACCESS
    1. Electrical reflex response of vago-vagal reflex was studied by stimulating the cervical vagus nerve of the right side and recording from the cervical vagus nerve of the left side.
    2. The electrical response of vago-vagal reflex can be grossely divided into three groups: constant 5-10 msec, latency response, labile 20-30 msec, and 60-90 msec. latency responses.
    3. These reflex responses are abolished by myanesin.
    4. Strychnine augments this reflex response and evokes the spontaneous burst-like discharge in higher doses.
    5. The responsible afferent fibers of reflex response are probably the B and delta fibers.
    6. Systemic cooling evokes the remarkable augmentation of vago-vagal reflex response.
    7. Mechanism of “Irritation syndrome” is discussed in connection with these observations.
    Download PDF (2044K)
  • YOICHI YAMAGUCHI, MASAHARU TSUCHIYA, TADAYOSHI AKIBA, MITSUYA YASUDA, ...
    1964 Volume 13 Issue 2 Pages 87-99
    Published: 1964
    Released on J-STAGE: March 27, 2009
    JOURNAL FREE ACCESS
    1. In two patiens suffering from urinary retention of various causes, appearance of arrhythmias were seen at the time of overdistension of the urinary bladder, which promptly disappeared by emptying of the bladder by catheterisation.
    2. Experimental overdistension of the urinary bladder in animals resulted in transitory fall of blood pressure, pictures of coronary insufficiency in EKG and/or appearance of arrhythmias. These changes disappeared by relieving the bladder of overdistension.
    3. In guinea pigs it was shown that the EKG changes produced by over-distension of the urinary bladder were erased by transection of the spinal cord between the lumbar and sacral segment.
    4. Using electrophysiological technic, it was shown that the nervous transmission from the bladder wall to the heart was related to vago-vagal reflex.
    This research was reported at the 11th Congress of the Japanese branch of the international neurovegetative research, on the 8th July 1962.
    Download PDF (4025K)
  • YUJI SUEYOSHI, YOSHIBUMI IMAI
    1964 Volume 13 Issue 2 Pages 101-106
    Published: 1964
    Released on J-STAGE: March 27, 2009
    JOURNAL FREE ACCESS
    Download PDF (301K)
  • UTAKO OKAMOTO, YUMIKO TAKADA
    1964 Volume 13 Issue 2 Pages 107-113
    Published: 1964
    Released on J-STAGE: March 27, 2009
    JOURNAL FREE ACCESS
    1. The extraction with hypertonic solution of KCI, KI, or sucrose showed a fairly high activity of plasminogen activator of the kidney parenchyma, while the KSCN extract of the kidney parenchyma failed to demonstrate the activity in rabbits.
    2. The activator extracted from frozen kidney showed stronger activity than that from the fresh tissue.
    3. The activator activity of kidney parenchyma was completely inhibited, when EACA or AMCHA was added to the standard fibrin plate.
    4. KCl-extracted activator of the kidney parenchyma of rabbit was rather stable at pH 7, despite of its lability at acid reaction.
    5. A rather higher activity of the activator was demonstrated with KSCN-extract than with KCl- or sucrose-extract from the kidney pelvis.
    6. From rat kidney two kinds of extracts were obtained concerned with pH stability; KSCN-extract was acid stable but destroyed at pH 7, KCl-extract was acid labile but showed rather high activity at pH 7, after heating for 30 minutes at 37°C.
    Download PDF (366K)
  • YUMIKO TAKADA, AKIKAZU TAKADA, UTAKO OKAMOTO
    1964 Volume 13 Issue 2 Pages 115-121
    Published: 1964
    Released on J-STAGE: March 27, 2009
    JOURNAL FREE ACCESS
    Download PDF (253K)
  • TAKEO UEDA, SHIGESHI TOYOSHIMA, TADAKAZU TSUJI
    1964 Volume 13 Issue 2 Pages 123-127
    Published: 1964
    Released on J-STAGE: March 27, 2009
    JOURNAL FREE ACCESS
    1) Guanidine nitrate (G.N.) was found to inhibit the multiplication of the K-2211 strain of common cold virus. Based on this finding, the method of screening for the K-2211 strain virus was arranged.
    2) According to the above screening method, 1-(p-substituted phenyl)-3-dimethylamino-1-propanols were screened as to their antiviral activities for the K-2211 strain virus. 1-Biphenylyl-3-dimethylamino-l-propanol was found to possess the almost equal activity with that of G.N.
    3) The relationship between the antiviral properties and the chemical constitution of 1-(p-substituted phenyl)-3-dimethylamino-l-propanols was dis-cussed.
    Download PDF (275K)
feedback
Top