The Keio Journal of Medicine
Online ISSN : 1880-1293
Print ISSN : 0022-9717
ISSN-L : 0022-9717
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Volume 13, Issue 3
Displaying 1-5 of 5 articles from this issue
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  • SEXUAL-CHROMATIN AND BREAST TUMORS
    THE RELATION BETWEEN SEXUAL-CHROMATIN AND HORMONE DEPENDENCY, AND DIFFERENTIATION OF CARCINOMA OF THE BREAST
    NOBUKATSU SHIMADA, HIROHARU MATSUDA, TAKEO AMAAKI
    1964 Volume 13 Issue 3 Pages 129-142
    Published: 1964
    Released on J-STAGE: March 27, 2009
    DOIhttps://doi.org/10.2302/kjm.13.129
    JOURNAL FREE ACCESS
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    Sexual-chomatin was microscopically counted following experiments during which rats were injected with sexual hormones and also during the examinations of human breast tissue. It was shown that the level of sexual-chromatin in animal tissue was dependent upon the level of estrogen, and that the level of sexual-chromatin of clinical cases responded well to the differentiation of carcinoma of the breast.
    From these results it is suggested that sexual-chromatin may be a clinical indicator of hormonal application to carcinoma of the breast.
    Notice: Our counts are significant beyond 0.003 probability of error.
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  • TRUE HERMAPHRODITES IN JAPAN
    REPORT OF A CASE AND REVIEW OF THE LITERATURE
    HIROSHI TAZAKI, NAOAKI IKEDA, SHUZABURO OMORI
    1964 Volume 13 Issue 3 Pages 143-154
    Published: 1964
    Released on J-STAGE: March 27, 2009
    DOIhttps://doi.org/10.2302/kjm.13.143
    JOURNAL FREE ACCESS
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    A case of true hermaphroditism was reported, in which bilateral ovotestes were found, drumstick was positive in 12 out of 500 polymorphous leukocytes of peripheral blood stream, and the chromosome karyotype was 46 XX.
    Fifty cases of true hermaphrodites reported in Japan were reviewed and briefly discussed.
    Grateful acknowledgement is made to Prof. H. Tamura, Assistant Prof. H. Tofukuji of Dept. of Urology, and Assistant Prof. H. Watanabe of Dept. of Pathology. Our thanks are also to Dr. K. Suzuki of Dept. of Urology.
    Our grateful acknowledgements are due to Dr. Akira Tonomura in the Dept. of Human Genetics, National Institute of Genetics, Mishima, Japan.
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  • FATTY LIVERS INDUCED BY AMINO ACIDS AND INFLUENCE OF OTHER AMINO ACIDS ON THEM
    YUJI SUEYOSHI, RYOICHI TOKUDA
    1964 Volume 13 Issue 3 Pages 155-164
    Published: 1964
    Released on J-STAGE: March 27, 2009
    DOIhttps://doi.org/10.2302/kjm.13.155
    JOURNAL FREE ACCESS
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  • PROLONGED HYPERPLASMINEMIA WITH MITOMYCIN C IN RABBITS
    REVERSIBLE DISAPPEARANCE OF TISSUE ACTIVATOR IN PARENCHYMA OF KIDNEY
    UTAKO OKAMOTO, YUMIKO TAKADA
    1964 Volume 13 Issue 3 Pages 165-172
    Published: 1964
    Released on J-STAGE: March 27, 2009
    DOIhttps://doi.org/10.2302/kjm.13.165
    JOURNAL FREE ACCESS
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    1. A long continued hyperplasminemia was produced by the consecutive administration of Mitomycin C to rabbits.
    2. An activator activity was observed in kidney parenchyma and kidney pelvis when the activator was extracted from fresh tissue with 2M KCI or 300/, sucrose.
    3. The activator activity of kidney parenchyma was completely disappeared after administration of Mitomycin C, while variation of the activity of pelvis was not significant even after the administration. The disappearance of activator activity was not explained by the increasing inhibitory action in kidney parenchyma.
    4. The recovery of the activator activity of kidney parenchyma was well demonstrated several days after ceasing the administration of Mitomycin C.
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  • MEASUREMENT OF CUTANEOUS CARBON DIOXIDE ELIMINATION IN MAN
    KAZUYA YAMAMOTO
    1964 Volume 13 Issue 3 Pages 173-176
    Published: 1964
    Released on J-STAGE: March 27, 2009
    DOIhttps://doi.org/10.2302/kjm.13.173
    JOURNAL FREE ACCESS
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    A gas chromatographic system for analysis of carbon dioxide delivered from the skin is described. The system utilizes a silica gel column arrangement for determination.
    The author is indebted to Dr. J. Kagawa, Dr. A. Takada, Mr. C. Sugimoto and Miss C. Kiire for their assistance.
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