The Keio Journal of Medicine
Online ISSN : 1880-1293
Print ISSN : 0022-9717
ISSN-L : 0022-9717
Volume 2, Issue 4
Displaying 1-4 of 4 articles from this issue
  • TAKASHI HAYASHI, ISAMU SUDA
    1953 Volume 2 Issue 4 Pages 125-140
    Published: 1953
    Released on J-STAGE: March 27, 2009
    JOURNAL FREE ACCESS
    1. In monkeys, the stimulation of the Area 4, 3-1-2 produced a focal epileptic seizure of which initial convulsion was determined by the site of stimulation within the areas.
    2. On the contrary, the stimulation of the Area 6 produced the generalized epileptic seizure from the beginning, but it produced a focal one, when a point of the Area 4 was preliminarily stimulated with subliminal strength for the seizure or when a sensory nerve of body was stimulated.
    3. During epileptic seizure which was produced by the stimulation of the motor or the extramotor cortex, when a part of the motor area (Area 4 in monkeys) was extirpated, the seizure was not changed, nor ceased, but the extirpation of the whole Area 4 made the seizure stop at once.
    4. If the above results are related as a form of law, the first law is “the law of initiation and continuation of epileptic seizure from motor cortex”. The second one is “the law of final common area for epileptic seizure from motor cortex”. The third law is “the law of substitution of cortex for epileptic seizure”. And the fourth law is “the law of pointing action of the motor area for the epileptogenic mode from the extramotor”.
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  • MISAO UEMURA, KIKUO KAWASHIMA, YOSHIO OGINO
    1953 Volume 2 Issue 4 Pages 141-148
    Published: 1953
    Released on J-STAGE: March 27, 2009
    JOURNAL FREE ACCESS
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  • SHOGO SASAKI
    1953 Volume 2 Issue 4 Pages 149-158
    Published: 1953
    Released on J-STAGE: March 27, 2009
    JOURNAL FREE ACCESS
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  • CHEMOTHERAPEUTIC DRUGS AGAINST VIRUSES XVI
    TAKEO UEDA, SHIGESHI TOYOSHIMA, TSUNEO WACHI
    1953 Volume 2 Issue 4 Pages 159-165
    Published: 1953
    Released on J-STAGE: March 27, 2009
    JOURNAL FREE ACCESS
    (1) PANS-No. 610 shows a remarkable effect on the Japanese encephalitis virus in vitro and in vivo. It is effective even at a longer interval after the inoculation of the virus.
    (2) The drug shows a weak effect in vitro and in vivo on the Lansing virus.
    (3) The drug possesses a comparatively low toxicity.
    (4) It is assumed that the effect of the drug on the Japanese encephalitis virus might be caused by its neurotropy, cerebrotropy and penetration-power into cells in host, related to its surfactant properties.
    (5) The drug is of promise for the treatment of the diseases caused by the Japanese encephalitis virus.
    (6) It may be claimed that the drug is the only compound which has been confirmed to have chemotherapeutic effects on patients suffering from the so-called small virus such as the Japanese encephalitis virus.
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