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Volume 42, Issue 4
Displaying 1-19 of 19 articles from this issue
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Toyomi Fujino1993 Volume 42 Issue 4 Pages 158
Published: 1993
Released on J-STAGE: March 27, 2009
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Yasuhiro Hosoda1993 Volume 42 Issue 4 Pages 159
Published: 1993
Released on J-STAGE: March 27, 2009
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Toyomi Fujino1993 Volume 42 Issue 4 Pages 160
Published: 1993
Released on J-STAGE: March 27, 2009
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Marvin P Fried1993 Volume 42 Issue 4 Pages 161
Published: 1993
Released on J-STAGE: March 27, 2009
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Soichiro Iwao1993 Volume 42 Issue 4 Pages 162-163
Published: 1993
Released on J-STAGE: March 27, 2009
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George S Abela1993 Volume 42 Issue 4 Pages 164
Published: 1993
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSLaser applications in the cardiovascular system have continued to evolve. These include methods of reducing shock wave effects during laser angioplasty, progress in the area of direct myocardial reperfusion, and electrophysiological applications.View full abstractDownload PDF (68K) -
Jeffrey S Dover, Suzanne Linsmeier Kilmer, R Rox Anderson1993 Volume 42 Issue 4 Pages 165-168
Published: 1993
Released on J-STAGE: March 27, 2009
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Peter McL Black, Charles Guttmann, Ferenc Jolesz1993 Volume 42 Issue 4 Pages 169-170
Published: 1993
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSThe applications of laser in both adults and pediatric neurosurgery are being steadily refined today. For many routine tumor removals, contemporary lasers do not add to ultrasonic aspiration or suction resection. However, there are some tumors in which one CO2 laser is invaluable; brain stem astro cytomas, skull base tumors, and intraspinal tumors are examples. Similarly, in resections of spinal lipomas they are useful to vaporize lipomas from the roots. Laser welding of vessels is technically possible but has generally not been useful. Perhaps the most exciting application is a combination of laser energy transfer with stereotactic technology. The MRI can be used to visualize structural changes in cerebral tissue. We have used this technology in 40 rats with gliomas and have been able to demonstrate destruction.View full abstractDownload PDF (102K) -
Marvin P Fried1993 Volume 42 Issue 4 Pages 171-173
Published: 1993
Released on J-STAGE: March 27, 2009
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Hideki Morita, Junro Kohno, Mika Hori, Yukio Kitano1993 Volume 42 Issue 4 Pages 174-176
Published: 1993
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSPatients with atopic dermatitis (AD) were treated with diode low reactive level laser therapy (LLLT), and the following results were obtained. 1) Itchy sensation decreased in 79 of 112 cases (71%) after this therapy. 2) Skin eruptions improved in 69 of 112 cases (62%). 3) There were no side effects during and after LLLT. 4) Major histocompatibility complex (MHC) class II antigen and inter-cellular adhesion molecule (ICAM)-1 expression on epidermal cells decreased after the therapy. 5) The number of CD1 positive epidermal dendritic cells did not significantly change before and after LLLT.View full abstractDownload PDF (209K) -
Mamoru Abe, Kazuhisa Fujisawa, Hiromi Suzuki, Tomoji Sugimoto, Tetsuo ...1993 Volume 42 Issue 4 Pages 177-179
Published: 1993
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSThe effect of low reactive level laser therapy (LLLT: 830nm, 60mW, continuous wave) was studied using the model of a glioma implanted in mice. Two different models were used. In the first model, therapies were applied post the first day of glioma implantation; in the second model, post the fourteenth day of glioma implantation. Using the first model, therapies were designed as follows. 1) control group (no therapy), 2) direct LLLT (15 seconds twice per day; on the skin covering the implanted glioma), 3) indirect LLLT (15 seconds twice per day; on abdominal skin area rather than the site of the implanted glioma), 4) indirect LLLT (30 seconds twice per day), 5) anti-cancer drug (ACNU) group, 6) mouse β-interferon (Mu-β-IFN) group, 7) direct LLLT plus Mu-β-IFN group, 8) ACNU plus Mu-β-IFN group, 9) indirect LLLT (15 seconds twice per day) plus ACNU plus Mu-β-IFN group. Using the second model, therapies were designed as follows. 1) control group (no therapy), 2) indirect LLLT (15 seconds twice per day), 3) indirect LLLT (15 seconds twice per day) plus Mu-β-IFN group, 4) Mu-β-IFN plus ACNU group. Our results indicated that, applied on the first day after glioma implatation, both direct and indirect LLLT were effective in inhibiting the tumor growth. In addition, it appeared that the effect of LLLT might be dose-dependent. Finally, the group of direct LLLT plus Mu-β-IFN was most effective in limiting the tumor growth and the incidence of growth as compaired with the other groups. However, when applied to the model fourteen days after glioma implantation, indirect LLLT contributed to tumor growth. LLLT (830nm, 60mW) may therefore be one of the biological responsive modifier's via skin tissue. Also, the active role of the LLLT in vivo model might depend on the biological interaction between the tumor bearing host and the tumor.View full abstractDownload PDF (179K) -
Takushi Tadakuma1993 Volume 42 Issue 4 Pages 180-182
Published: 1993
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSThe human immune system acts a defence mechanism against exogenous or indigenous potentially harmful bodies, such as bacteria and viruses. The major histocompatibility complex (MHC class I and class II antigens) form key elements of legitimate body components, and the organization of MHC molecules allows T-lymphocytes to distinguish between legitimate and foreign bodies. On detection of a foreign component, T-cells activate the necessary pathways for destruction of the foreign body. Occasionally however the system breaks down and the result is a disease of an autoimmune nature. Both visible light and infrared low reactive-level laser therapy (LLLT) has been shown to act on immune system cells in a number of ways, activating the irradiated cells to a higher level of activity. Infrared LLLT has been shown to increase both the phagocytic and chemotactic activity of human Leukocytes in vitro, for example. This is an example of photobiological activation. Photobiological cell-specific destruction is also possible using doses of low incident laser energy on cells which have been photosensitized for the specific wavelength of the laser, such as in photodynamic therapy (PDT) for superficial cancers. LLLT has also been shown to act directly and selectively on the autoimmune system, restoring immunocompetency to immunoincompetent cells. Although much more research needs to be done, there are enough experimental and clinical data to show that the laser, and LLLT in particular, has a possibly exciting role both in immunobiological therapy for diseases of the immune system, and to activate and boost the normal reaction of the immune system components against harmful foreign bodies.View full abstractDownload PDF (209K) -
Tsunenori Arai, Kyoichi Mizuno, Makoto Kikuchi1993 Volume 42 Issue 4 Pages 183-185
Published: 1993
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSA unique percutaneous transluminal coronary angioplasty system using new infrared therapy laser with infrared glass fiber delivery under novel angioscope guidance was described. Carbon monoxide (CO) laser emission of 5 mm in wavelength was employed as therapy laser to achieve precise ablation of atheromatous plaque with a flexible As-S infrared glass fiber for laser delivery. We developed the first medical CO laser as well as As-S infrared glass fiber cable. We also developed 5.5 Fr. thin angioscope catheter with complete directional manipulatability at its tip. The system control unit could manage to prevent failure irradiations and fiber damages. This novel angioplasty system was evaluated by a stenosis model of mongrel dogs. We demonstrated the usefulness of our system to overcome current issues on laser angioplasty using multi-fiber-catheter with over-the-guidewire system.View full abstractDownload PDF (3496K) -
Haruyuki Minamitani, Eiji Okada1993 Volume 42 Issue 4 Pages 186-190
Published: 1993
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSA microscopic laser Doppler velocimeter to measure blood velocity in single microvessels was developed. In order to measure the blood velocity in microvessels correctly, the influence of stray scattered light from vessel wall should be removed. Because it provokes low-frequency spurious components. The spectra of the spurious components overlap with that of Doppler signal and induces considerable error in the result of the blood velocity when the velocity is reduced. The optical configuration of the velocimeter was optimized to eliminate the influence of the stray scattered light. The blood velocity in microvessels in rat mesentery was measured with the microscopic laser Doppler velocimeter and the periodical fluctuation of the velocity was analyzed. Pulsatile velocity fluctuation could be observed even in capillary.View full abstractDownload PDF (341K) -
Toshio Ohshiro, Toyomi Fujino1993 Volume 42 Issue 4 Pages 191-195
Published: 1993
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSVery shortly after the laser's first successful firing in 1960, applications were found in the medical field in the specialities of ophthalmology and dermatology and have since expanded to include indications in plastic and reconstructive surgery. In the photodestructive mode, laser energy is used selectively to vaporize, incise, excise, ablade and coagulate target tissue; the surgical laser can also degrade or denature protein in the target tissue, and the latter photoreaction now forms the basis for laser tissue welding in a variety of tissue types. The author refers to these photodestructive applications as high reactive level laser treatment, or HLLT. In laser therapeutic applications, the temperature of the cells may rise only very slightly or not at all, and there is no immediate irreversible change in the target tissue architecture. The level of reaction is thus lower than the cell survival threshold, giving a direct photoactivative effect. The author refers to this as low reactive-level laser therapy, or LLLT: LLLT applications include pain attenuation, wound healing acceleration; enhanced remodeling in accelerated bone and tendon repair; restoration of normal neural function; normalization of abnormal hormonal function; modulation of the autoimmune system; control of hyper and hypotension and so on. HLLT and LLLT are contrasted and compared, and applications of both HLLT and LLLT in PRS are discussed in brief.View full abstractDownload PDF (3227K) -
Katsumi Tsukazaki, Kazushige Kiguchi, Shiro Nozawa1993 Volume 42 Issue 4 Pages 205
Published: 1993
Released on J-STAGE: March 27, 2009
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Mamoru Watanabe, Yoshinori Sugino, Yutaka Imai, Koichiro Kumai, Toshif ...1993 Volume 42 Issue 4 Pages 206-208
Published: 1993
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSThe efficacy and safety of the endoscopic laser therapy for eradication of early cancer in the stomach was revaluated in fourty-eight patients. In 37 of the 42 patients (88%) treated with the laser therapy alone, the procedure was effective and the complete eradication was confirmed at the end of the follow-up period. In seven of fourteen patients with the incomplete treatment, residual cancer cells were successfully removed by repeated laser therapy. The endoscopic mucosal resection was effective in 21 of the 30 patients (70%) with the early gastric cancer. Interestingly, six of the eleven cases with incomplete treatment with the endoscopic mucosal resection underwent the laser therapy and the complete eradication was achieved in all patients. Although the endoscopic mucosal resection is now the main method for the endoscopic treatment of the early gastric cancer, these data favor offering the endoscopic laser therapy as the combined method with the mucosal resection therapy.View full abstractDownload PDF (201K) -
Shiro Baba, Hiroshi Asanuma, Hiroshi Tazaki1993 Volume 42 Issue 4 Pages 209-211
Published: 1993
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSThe efficacy of the second generation dye-laser lithotriptor (Pulsolith) with high power output was studied in 35 patients with ureteral stones. Ninety per cent of the calcium oxalate monohydrate stones were fragmented, although it required more total energy as compared to that delivered to calcium oxalate dihydrate or phosphate stones. Cystine stones remain resistant to dye-laser lithotripsy. The calculi including cystine stone were immersed in rifampicin or tetracycline solutions and the effect of optical coupling on fragmentation efficacy was measured in vitro. The optical coupling seemed to improve photo-acoustic effect, but the fragmentation rate for cystine stones remained only 10 per cent of that for calcium oxalate.View full abstractDownload PDF (243K) -
Nobuyoshi Shimizu, Shinsei Minoshima, Jun Kudoh, Kazuhiko Kawasaki, Yi ...1993 Volume 42 Issue 4 Pages 212-216
Published: 1993
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSMore than 30 human genes have been mapped by a combination of the fluorescent in situ hybridization (FISH) and spot blot hybridization in this laboratory for the past five years. Furthermore, the Keio strategy has been established for the molecular analysis of the human genome using flow-sorted human chromosomes.View full abstractDownload PDF (2046K)
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