The KITAKANTO Medical Journal
Online ISSN : 1883-6135
Print ISSN : 0023-1908
ISSN-L : 0023-1908
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Volume 12, Issue 3
Displaying 1-5 of 5 articles from this issue
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  • [title in Japanese]
    [in Japanese]
    1962 Volume 12 Issue 3 Pages 169-184
    Published: 1962
    Released on J-STAGE: February 22, 2010
    DOIhttps://doi.org/10.2974/kmj1951.12.169
    JOURNAL FREE ACCESS
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  • AN AUTOPSY CASE OF HODGKIN'S SARCOMA ACCOMPANING WITH THE REMARKABLE LEUCOCYTOSIS IN A GIRL
    Kiyoshi Sasdmoto, Kenzi Aoki, Kashiro Aida
    1962 Volume 12 Issue 3 Pages 185-198
    Published: 1962
    Released on J-STAGE: November 11, 2009
    DOIhttps://doi.org/10.2974/kmj1951.12.185
    JOURNAL FREE ACCESS
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    This report deals with a autopsy case of Hodgkin's sarcoma in a 7 years girl. Principal clinical findings are swelling of lymphonodules around the neck and splenomegaly. In the peripheral blood anemia and remarkable leucocytosis contained a small number of myeloblasts and a great deal of the atypical monocytoid cell (Hodgkin's cell) are noticed.
    Pathoanatomical finding :
    1. Swelling of lymphonociules in the whole body and the thyroid gland.
    2. Metastatic tumor formation in the heart, the lungs, the pleura, the kidney, the pancreas and the diaphragm.
    3. Splenomegaly with a curious porphyry-like appearance.
    4. Atelectasis of the left lung and upward displase of the left diaphragm.
    5. Pleural effusion (100cc) and ascites (300cc) etc.
    Pathohistological finding :
    Lymphatic tumor tissue is constituted very variously with the proliferous reticulum cell, Hodgkin's cell, Sternberg's giant cell, fibroblast, collagenic fiber, lymphocytes and coagulative necrosis. And then some part of proliferous reticulum cell is characterized by pleomrorphism and mitosis of the nucleus and infiltrated character. Therefore, it is considered that this lymphatic tumor belong to a type of the Hodgkin's sarcoma.
    In the myeloid tissue, free enlarged reticulum cell (tumor cell) infiltrated diffusely and hematopoesis is held normality. Because we supposed that remarkable leucocytosis in the peripheral blood is due to the leukomoid reaction as a result of metastatic tumor formation in the myeloid tissue.
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  • LOCAL PATHOLOGICAL CHANGES FOLLOWING INJECTION OF HEAT-STABLE SUBSTANCES IN THE HABU-SNAKE (TRIMERESURUS FLAVOV IRIDIS) VENOM
    Takashi Okonogi, Shoji Hoshi, Manabu Homma, Kenzaburo Suto, Hisayoshi ...
    1962 Volume 12 Issue 3 Pages 199-207
    Published: 1962
    Released on J-STAGE: November 11, 2009
    DOIhttps://doi.org/10.2974/kmj1951.12.199
    JOURNAL FREE ACCESS
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    An injection of Habu-snake venom, heated for 10 minutes at 100°C., caused myolysis at the site, histologically. But different from crude venom action, no hemorrhagic changes were recognized. At first, disappearance of mitchondria in the muscular fibers was seen, and then muscular splitting and lysis followed.
    While the myolytic changes caused by crude venom began immediately af ter the injection, the beginning of the changes were delayed when the heated material were used.
    Anti-Habu-serum neutralised the toxicity of the heated venom, and also, E.D.T.A.-Ca, Cocarboxylase and α-Thiolactoylglicine-Na repressed the toxicity in vitro.
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  • ON THE CHEMICAL EFFECTS OF THE PURIFIFD A-AND B-DECOMPOSING ENZYMES ON BLOOD GROUP A AND B SUBSTANCES
    Shigeru Yamamoto, Keiichi Fujisawa
    1962 Volume 12 Issue 3 Pages 208-225
    Published: 1962
    Released on J-STAGE: November 11, 2009
    DOIhttps://doi.org/10.2974/kmj1951.12.208
    JOURNAL FREE ACCESS
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    1. The A-decomposing enzyme preparation purified from a culture filtrate of Clostridium tertium has an ability to destroy the A activity of human A blood group substance, releasing from it galactose, N-acetylgalactosamine, N-acetylglucosamine, and N-acetylmannosamine as simple sugar as well as a disaccharide which is presumed to be N-acetylgalactosaminoyl- (1→3) -D-galactose. Thus, the enzyme preparation contains a type of β-D-galactosidase which liberates from A substance galactose and galactose-containing disaccharide, and also N-acetylhexosaminidase (s) which liberates N-acetylhexosamines.It is considered from these results that the component sugar of A substance derived from human gastric linings consits of L-fucose, D-galactose and in addition, aminosugars such as N-acetylgalactosamine, N-acetylglucosamine, and N-acetylmannosamine.
    2. It is deduced that the B-decomposing enzyme preparation purified from a culture filtrate of Clostridium maebashi destroys the B activity of human B blood group substance to release from it D-galactose, non-reducing end galactosyl residue combined with second sugar probably through α-1→6 or 1→3 linkage. The enzyme preparation contains an enzyme which would be nominated B-decomposingα-D-galactosidase, because of failure to release any component sugar of B substarce except D-galactose and also to hydrolyze α-linked D-galactose-containing oligosaccharides such as melibiose, stachyose, and verbascose.
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  • [title in Japanese]
    1962 Volume 12 Issue 3 Pages 226
    Published: 1962
    Released on J-STAGE: November 11, 2009
    DOIhttps://doi.org/10.2974/kmj1951.12.226
    JOURNAL FREE ACCESS
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