北関東医学
Online ISSN : 1883-6135
Print ISSN : 0023-1908
ISSN-L : 0023-1908
12 巻, 5 号
選択された号の論文の6件中1~6を表示しています
  • 辻 達彦
    1962 年 12 巻 5 号 p. 287-297
    発行日: 1962年
    公開日: 2009/11/11
    ジャーナル フリー
  • 古川 研, 井関 尚栄, 石原 恵三
    1962 年 12 巻 5 号 p. 298-309
    発行日: 1962年
    公開日: 2009/11/11
    ジャーナル フリー
    1) In anti-stomach cancer polysaccharide rabbit serum, was found a precipitin which reacted with stomach cancer polysaccharide, and this antibody was absorbed with D-galactosamine hydrochloride and D-glucosamine hydrochloride. This antiserum did not react with purified O(H), Lea, A and B substances.
    2) O(H) substance in stomach cancer polysaccharide had generally weaker activity than that of polysaccharide from normal human stomach linings. The stomach cancer polysaccharides which had especially weak O(H) activity and strong Lea activity, and which had almost lost both O(H) and Lea activity strongly reacted with anti-stomach cancer polysaccharide rabbit serum. When O(H) substance was treated with an enzyme from a certain strain of Cl, tertium which decomposes O(H) and Lea substances and common antigenic substance between blood group substances and Diplococcus pneumoniae Type XIV, it came to precipitate with the antiserum mentioned above. It was subsequently estimated that so far as the stomach cancer polysaccharide concerns, an antigenicity which remains latent covered by other antigenic determinants in the normal stomach tissue, would be manifested in cancer tissue owing to abnormal proliferation.
    3) Polysaccharide from placental tissue reacted with anti-stomach cancer polysaccharide rabbit serum. And in antiserum, obtained by immunizing rabbit with this polysaccharide, was produced a precipitin, which reacted with enzyme-treated O(H) substance, and absorbed with D-galactosamine hydrochloride and D-glucosamine hydrochloride.
  • HW-1抗原の鈎虫卵陽性者並びに鈎虫卵陰性者に対する皮内反応
    沢田 利貞, 河野 恵, 佐藤 重房, 武井 一利
    1962 年 12 巻 5 号 p. 310-315
    発行日: 1962年
    公開日: 2009/11/11
    ジャーナル フリー
    Intradermal tests were carried on using antigen HW-1 prepared from the adult worms of Ancylostoma caninum, in injection of 0.01 ml of the antigen in a dilution of 1 : 100, 000 and the reactions were read 15 minutes after the injection by measuring the mean diameter of the wheal and the erythema. Similar tests were conducted using physiologic saline as an control, and the following results were obtained.
    Both wheal and erythema appeared by the injection of the antigen HW-1 When the mean diameter of the wheal elicited by the injection of the anitgen was over 9mm, the reaction was considered as positive, and when the mean diameter of the erythema elicited by the injection of the antigen was over 26mm, the reaction was considered as positive.
    The wheal appeared in 86.7% and the erythema appeared in 81.3% of the hookworm carrier.
    Then it is preferable to determine that the reaction is positive by the size of the wheal better, than that of the erythema.
    The wheal, elicited by the injection of saline, did not exceed over 9.0mm in every case.
  • 第1報 血清マグネシウムとの関係
    塚田 穣
    1962 年 12 巻 5 号 p. 316-323
    発行日: 1962年
    公開日: 2009/11/11
    ジャーナル フリー
    Investigation was performed on the role of salt, especially magnesium and calcium salt, in the formation of sero-xelo-gel figure (Shichijo's reaction), and the following results were obtained.
    1) When natrium salt of EDTA was added to type I serum, it was converted into type IX.
    2) Magnesium solution like calcium solntion could turn type IX serum negative.
    3) After addition of the same amounts of magnesium and calcium solutions, sero-xelo-gel figures were compared with each other, and it was found out that the former had rather stronger power to produce the figure.
    4) In the formation of the figure, magnesium and calcium ions were colloidchemically neither antagonistic nor synergic.
    5) Dilution turned type I serum positive. Also statistically, higher serum whole protein group gave higher positivity rate (types V ).
  • 第1編脾及びリンパ節の組織像について
    笹本 潔
    1962 年 12 巻 5 号 p. 324-333
    発行日: 1962年
    公開日: 2009/11/11
    ジャーナル フリー
    In this paper, the histopathological study of the spleen and the lymph nodes of mice having infected with virulent or attenuated S. enteritidis, was reported as a part of fundamental study of experimental salmonellosis.
    The group of mice infected with 10-7 mg or 10-2 mg microorganismus of virulent strain, almost died within 6 days in cause of septicaemia. On the contrary, the group with 10-5 mg of attenuated strain were no death entirely, and that obtained high igrade immunity 3 weeks after infection.
    Pathohistologically, the spleen and the lymph nodes of mice with virulent strain showed a few tubercule, multiple necrosis in the reticular tissue, and many bacterial colonies in the blood vessel and necrotic tissues. On the other hand, mice with attenuated strain exhibited formation of multipel tubercules, reticuloendotheliosis and no bacterial colony, in the spleen and the lymph nodes, and that proliferatiion of myeloid cells sround the trabeculae of the spleen, multiplication of plasma cell with many Rassel, s bodies and reticular stimulating cells (Lennert) on the lymphatic medullary cord, were characterized by this group.
    It is considered that those several pathohistological finding were related to reaction of mechanism immunized with living bacteria, as well as tubercule.
  • 田村 寛
    1962 年 12 巻 5 号 p. 339-355
    発行日: 1962年
    公開日: 2009/11/11
    ジャーナル フリー
    (i) Assay of PBI by Zak-Leffer's chloric acid method was reduplicated, and its reliability was confirmed.
    This method has advantage in that it is more simple and more rapidly performed than other methods, and can assay many samples at a time.
    (ii) PBI value for normal women as assayed by the chloric acid method ranged 3.27.0γ/dl, And it was found to be higher in luteal phase than in ovulatory phase.
    (iii) During pregnancy, especially in early period, PBI value was rather high, but in puerperium, it returned to the normal level.
    (iv) Pregnant women and patients with secondary amenorrhea complicated with various thyroid diseases were investigated for symptoms and hormones, and relation between gonad and thyroid was discussed.
    (v) After hysterosalpingography, which is frequently used in the field of obstetrics and gynecology, assayed values of PBI were sometimes abnormally high. Investigation was performed on its change and effect on thyroidal function.
    (vi) In patients with cervical cancer, PBI was assayed before and after operation without any consistent results. In cases who died from the relapse of the cancer immediately after the operation, PBI tended to decrease, while in cases without the relapse in one year after the operation, the value was higher than before the operation.
    (vii) In this way various, investigations were performed by means of PBI assay. As to correlation between gonad and thyroid, results of a definite tendency could not always been obtained, and details still remained to be investigated.
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