The KITAKANTO Medical Journal
Online ISSN : 1883-6135
Print ISSN : 0023-1908
ISSN-L : 0023-1908
Volume 13, Issue 6
Displaying 1-6 of 6 articles from this issue
  • [in Japanese]
    1963 Volume 13 Issue 6 Pages 335-339
    Published: November 01, 1963
    Released on J-STAGE: October 15, 2009
    JOURNAL FREE ACCESS
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  • Miyoko Ooyama
    1963 Volume 13 Issue 6 Pages 340-354
    Published: November 01, 1963
    Released on J-STAGE: October 15, 2009
    JOURNAL FREE ACCESS
    Two cases with acute intermittent porphyia were investigated clinically, and the following results were obtained.
    1) Typical gastro-intestinal, neurological and cardiovascular symptomes as acute intermittent porphyria were observed during the clinical course of these two cases. Chemical analyse of urine from both cases revealed an increased excretion of porphobilinogen and δ-amino laevulinic acid.
    2) Generalized muscular atrophy was one of the prominent features of acute phase in any of these cases. Creatinuria was detected in one case with severe muscular athrophy in acute phase of the disease. But excretion of creatinine was not increased significantly.
    3) No remarkable changes were observed in activity of creatine-phosphokinase and Aldolase of serum.
    4) Analysis of electromyogram revealed that muscular atrophy observed in both cases resulted from both myogenic and neurogenic disturbances.
    5) Atrophy of whole muscular fibers was observed in histological sections of M. quadriceps femoris obtained by biopsy. But no changes in interstitial tissue could be found.
    6) Creatin excreted to urine was decreased to normal level, after the recovery from muscular atrophy. No abnormalities were detected in electromyogram after the complete recovery from muscular atrophy.
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  • H. Hosaka
    1963 Volume 13 Issue 6 Pages 355-367
    Published: November 01, 1963
    Released on J-STAGE: October 15, 2009
    JOURNAL FREE ACCESS
    I. Clinical observation of the “rebound phenomenon” of human ovarian function The so-called “rebound phenomenon” by Matsumoto anp Igarashi was.
    clinically reexamined, and especially the indication and application of this phenomenon were studied with the following results.
    1) Debouts pill of estrogen or estradiol benzoate was given to 162 sterile women in the for mer half of the menstrual cycle, and as the result ovulation was inhibited in 79.5% the high phase of BBT was prolonged in the succeeding cycles of its 51.9%, and 17.8% became pregnant
    2) Improvement was produced by this treatment in cases with remrkable luteal dysfunction and the high phase of BBT lasting 79 days, but pregnancy was induced in few of them.
    Pregnancy, however, occurrd in many with the 1012 dayhigh phase, which was slightly shortened by this treatment.
    3) In 2 out of 4 cases with anovulatory cycle, ovulation was induced by the treatment, but the rebound effect was not certain.
    4) Out of the used estrogen preparations, estradol valevianate had highest efficacy.
    5) To produce the rebound effect, it is necessary to inhibit ovulation. And for this purposeit is desirable that estrogen may begiven within 7 days of the menstrual cycle.Also cervical mucus gives the indication of the adequate time of the administration.
    6) The rebound effect was not observed in the administration of 19-norsteroids, especially norethysterone.
    7) In addition, a few rebounb phenomena of other special types were observed and discussed.
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  • II. Endocrinological observation of the rebound phenomenon of human ovarian funfunction
    H. Hosaka
    1963 Volume 13 Issue 6 Pages 368-379
    Published: November 01, 1963
    Released on J-STAGE: October 15, 2009
    JOURNAL FREE ACCESS
    By assaying various urinary hormones, especially gonadotropin, it was investigated whether the rebound phenomenon of the human ovarian function can be regarded as belonging to a series of reactions of the hypophyseo-ovarian system.
    1) After administration of Debout's pill of estrogen, Crook & Butt's GA and GB were determined. The results showed that these frac-tions were increased in the ovulatory and luteal phase of the rebound cycle. According to the biological assay, thg fractions tended to increased in the follicular and ovulatory phase.
    2) Three spayed women were given 10 mg of benzesterol, and GA and GB were found remarkably increased over the pre-adminis-tration values, indicating the rebound phenomenon in gonadotropin.
    3) Further, estrogen and 17-KS tended to increase in the rebound cycle, but no remarkable change in 170HCS.
    4) There were no remarkable increase in GA and GB after administration of 19-norsteroid.
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  • HIDEO ISHII, HIROSHI KANEKO, ISUZU KAWABATA
    1963 Volume 13 Issue 6 Pages 380-387
    Published: November 01, 1963
    Released on J-STAGE: October 15, 2009
    JOURNAL FREE ACCESS
    Statistical observations were performed from April 1957 through March 1963 on 60 inpatients with laryngeal tumor in Department of Oto-rhino-laryngology, School of Medicine, Gunma University, and the results were discussed from various viewpoints. Especially laryngeal tumor was divided into 6 types by the international classification (1961), and comments in literatur were made on it. It goes without saying that early discovery and early diagnosis are the prerequisite for the treatment of malignant tumors. However, prognosis of tumors was largely dependent not only on early discovery but also on the site and extension of tumors. Since laryngeal tumor has high recovery rate, pronounciation training after laryngectomy will become increasingly important as a means of rehabilitation.
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  • PRELIMINARY SURVEY OF AN ASSOCIATION BETWEEN WATER FACTOR AND PREVALENCE OF RAISED BLOOD PRESSURES
    Tatsuhiko Tsuji, Minoru Tsukada, Goro Kojima, Masao Nitta, Sukeshi Fuj ...
    1963 Volume 13 Issue 6 Pages 388-393
    Published: November 01, 1963
    Released on J-STAGE: October 15, 2009
    JOURNAL FREE ACCESS
    Preliminary survey of an association between drinking water and prevalence of raised blood pressures in a small rural population (pop. 370) was reported. There has been a belief among the natives that local accumulation of hypertensive patients was due to drinking water from particular springs, which were primary source of drinking uses until 1959 when the water supply system was established. Blood pressure measurements and morbidity investigation revealed the followings : The greater prevalence of hypertensive patients in the population as compared with neighbouring communities was not conclusive. However, it was disclosed that the families which had used spring water showed more hypertensive patients than the families with wells, although the statistical significance was not attained. It was also felt that suitable control families were so scarce in the same region that epidemiological findings were insufficient. Therefore, no estimate of added risk from causative agent, if ever, in spring water was given. (Chemical analysis of drinking waters will be reported in a following paper.)
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