北関東医学
Online ISSN : 1883-6135
Print ISSN : 0023-1908
ISSN-L : 0023-1908
15 巻, 6 号
選択された号の論文の9件中1~9を表示しています
  • 藤森 正雄, 安斉 徹男
    1965 年 15 巻 6 号 p. 411-417
    発行日: 1965/11/01
    公開日: 2009/10/15
    ジャーナル フリー
  • 2. 免疫操作による感染像の修飾
    福富 義典
    1965 年 15 巻 6 号 p. 418-424
    発行日: 1965/11/01
    公開日: 2009/10/15
    ジャーナル フリー
    Immunization with dead vaccine activates phagocytosis by RE cells. Increase of 0 antibody also plays a role in effective opsonizing. Marked effect is found especially when challenge is done at the same area of immunization. Usually, growth of intracellular bacteria and subsequent death of challenged mice is not inhibited after the immunization with dead vaccine. In the case of immunization with live vaccine, on the other hand, clearance of challenged bacteria seems to be rather weak, but intraceelluler growth of bacteria or re sultingsepsis is inhibited.
    These cellular immunity is found only in some group of RE cells. In the case of subcutaneous challengeethe first infiltration and phagocytosis by polymorphnuclear cells never suppress the grow th of bacteria, and only after the appearance of largemonuclear cells, the course of infection is interrupted. Principal participants in cellular immunity with live vaccine are larger mononuclear cells and are not polymorphnuclear cells.
  • 古川 研
    1965 年 15 巻 6 号 p. 444-452
    発行日: 1965/11/01
    公開日: 2009/10/15
    ジャーナル フリー
    Treatment with enzyme preparation from Clostridium tertium O(H), Lea destroys O(H) and Lea or Leb activities and cross reactivity with anti-Diplococcus pneumoniae Type XIV chicken serum of OLe(a+b-) and OLe(a-b+) erythrocytes and glycolipids from them. After enzyme treatment, fucose, galactose and N-acetylglucosamine are liberated from these red cells and glycolipids as monosaccharides. These results are similar to that of the enzyme action on the water-soluble blood group substances. Galactose and N-acetylglucosamine are assumed to be the determinants of the cross reactivity with anti-Diplococcus pneumoniae Type XIV chicken serum of blood group substances from red cells.
  • 小菅 隆夫, 本間 学, 小此木 丘
    1965 年 15 巻 6 号 p. 453-458
    発行日: 1965/11/01
    公開日: 2009/10/15
    ジャーナル フリー
    Neutralizing effects of Cepharanthin and Metabolase on the crude and the heated venom of Habu snake were investigated in vitro,
    1. Cepharanthin 500γ/0.1 ml and Metabolase 100γ/0.1 ml inhibited or reduced the haemorrhagic action of a dose of less than 125γ of Habu snake venom, and also inhibited the lethal activity of the same dose of the venom.
    2. However, both drugs had scarcely any inhibitory action on the myo-lytic changes produced by the crude and the heated venom.
    3. When Cepharanthin and Metabolase were used in combination, the effect which can not be gained with either of these drugs separately was recognized.
  • 松山 研二, 大根田 玄寿, 沢渡 誠志, 牛久保 量平
    1965 年 15 巻 6 号 p. 459-468
    発行日: 1965/11/01
    公開日: 2009/10/15
    ジャーナル フリー
    The effects of FK-482 (Fujisawa Pharm. Co.) and vitamin E on atherosclerosis were investigated in cholesterol-fed rabbits. FK-482 is a new compound, which is synthesized with vitamin E and ferulic acid, and may possess the properties of an antioxidant.
    1. FK -482 affords a fairly good degree of protection against aortic atherosclerosis.
    2. Vitamin E protects also against aortic atherosclerosis, but is less effective than FK- 482.
    3. FK-482 accelerates the reduction of high serum cholesterol level after suspension of cholesterol feeding.
    4. Lipid deposition in the reticuloendothelial system is conspicuous in rabbits treated with FK-482.
  • 森村 正東, 手島 栄三郎, 阪本 亨吉, 橋本 一, 堀川 謹三, 三橋 進
    1965 年 15 巻 6 号 p. 469-477
    発行日: 1965/11/01
    公開日: 2009/10/15
    ジャーナル フリー
    1) Isolation frequency of SM-resistant S. aureus in field survey has been decreasing year by year.
    2) SM-resistant strains which had been stocked in our laboratory for long months, often lost their SM-resistance. Meso-SM-resistance was more unstable than high SM-resistance.
    3) Mutation frequency from sensitivity to SM-resistance was examined for 22 strains. High-resistant colonies were more frequently isolated than meso-resistant ones.
    4) Genetically, high SM-resistance is rather stable and often links to TC, high PC and SA resistance.
  • 金子 寛
    1965 年 15 巻 6 号 p. 478-481
    発行日: 1965/11/01
    公開日: 2009/10/15
    ジャーナル フリー
    The patient was 11 years old girl with complaint of tumor in the anterior medial part of the neck. Before operation, the tumor seemed to be fibroma or chondroma for it's hardness and findings on scintigram. Detailed histopathological examinations of the tumor revealed it to be the papillary adenocarcinoma of aberrant thyroid gland. The patient, after operation, was given a course of irradiation therapy of 10, 000γ by the tele-cobalt. She seems to be in favourable condition today 15 months after operation.
    This patient's tumor occured in aberrant goiter which developed from the rest of thyroglossal duct, and grew up malignantly into adenocarcinoma.
  • 大前 暹二, 馬場 隆
    1965 年 15 巻 6 号 p. 482-484
    発行日: 1965/11/01
    公開日: 2009/10/15
    ジャーナル フリー
    A sixteen year old boy complained of difficulty in tongue movements because of the presence of a tumor, which was gradually enlarged since his birth, at the left side the tongue. The tumor was removed surgically and was examined histologically. The histological examination revealed that tumor was composed of the tissue similar to that of normal tongue. Therefore the tumor was a developmental anomaly of rare occurrence and was not a so-called true tumor. No reccurence was observed three years after operation.
  • 第2報 螢光抗体法による実験的アレルギー性結膜炎の研究
    管野 雄行
    1965 年 15 巻 6 号 p. 485-491
    発行日: 1965/11/01
    公開日: 2009/10/15
    ジャーナル フリー
    (1) Using the pollen of Pinus Thumbergii as an antigen, allergic conjunctivitis was experimentally provoked in male albino rabbits, and by means of fluorescence, relation between the circulating antibody 2nd the tissue antibody on the 35th day after the beginning of the experiment, and the effect of 6 -MP on the antibody were observed.
    (2) Fluorescences in the whole area of the conjunctiva were conspicuously more numerous in the sensitized than in the non-sensitized group, and the circulating antibody and antibody-producing (or containing) cells were approximately in parallel relation.
    (3) Comparison between the antigen-administered and the non-administered eye samples revealed that fluorescences were significantly more numerous in epithelial cells of the foimer than in those of the latter.
    (4) When the production of the circulating antibody was inhibited by oral administration of 6-MP, a mitotic poison, the incidence rate of fluorescence was lowered. And there was ample parallel relation between the fluorescence and the circulating antibody.
    (5) One and the same sample was twice stained with hematoxylin-eosin to identify the antibody producing or containing cells, and it was confirmed that not only lymphocytes and plasma cells but also eosinophils and pseudo-eosinophils were fluorescent.
    (6) As reported in the previous paper, eosinophils and pseudoeosinophils were observed more remarkably in the sensitized than in the non-sensitized animals. Specific features of their fluorescence will be studied later.
feedback
Top