巻号一覧
21 巻, 2 号
選択された号の論文の5件中1～5を表示しています
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北条 靖1971 年 21 巻 2 号 p. 81-93
発行日: 1971年
公開日: 2010/02/09
ジャーナル フリーThis report is concerned with adjuvant chemotherapy of gastric cancer. Since 1962, we had_ tried gastric arterial infusion of anti-cancer agents during radical operation of stomach cancer.
Recently, Hepatic arterial infusion has been combined simultaneously with gastric arterial infusion. The side effects of Mitomycin C (MMC) and 5-Fluorouracil (5-FU) on the iron metabolism in the bone marrow in regard to ferrokinetics and hematopoietic impairment produced by that infusion treatment were studied after Huff's method.
1) In blood picture and liver function, there were little disorder.
2) Plasma iron disappearance time 1/2 (PIDT 1/2) markedly increased postoperatively after 4 days, but after 14 days, it was about the same as the preoperative.
On the other hand, during the past three years in our surgery, 5-FU was administered intravenously of 55 patients with carcinoma or sarcoma of the stomach.
3) The toxicity of the drugs was found in patients subjectively and in 3 cases objectively, and the common toxic reactions were as follows : 9 diarrhea, 6 loose stool, 5 nausea and vomiting, 4 general fatigue, 4 anorexia, 1 stomatitis; 2 liver disorder, 1 leucopenia.
4) For the purpose of prevention of these toxic reactions, Inosine, Vitamin B6 and B12, and Glutathione were given to patients after surgery, with a little favorable effect.抄録全体を表示PDF形式でダウンロード (1825K) -
第13報局所Shwartzman反応における免疫粘着現象 (予報)鈴木 成欣, 松村 龍雄1971 年 21 巻 2 号 p. 94-103
発行日: 1971年
公開日: 2009/10/15
ジャーナル フリーIn an attempt to clarify the mechanism of the local Shwartzman reaction, immunological investigation using immune adherence phenomenon was carried out. And the following results were obtained.
1) Normal rabbits were found naturally sensitized to the endotoxin.
2) After the preparatory injection, the serum complement was decreased and the antibody forming cells in the spleen appeared.
3) After the provocative injection, in vitro clumping as well as rosette formation of the leucocytes by adding complement and endotoxin were intensified.
On the basis of these findings, the role of immune complex and immune adherence phenomenon in the etiology of the local Shwartzman reaction was discussed.抄録全体を表示PDF形式でダウンロード (2899K) -
その1 “におい” 識別の学習と嗅神経の経路傷害の影響牧野 総太郎1971 年 21 巻 2 号 p. 104-113
発行日: 1971年
公開日: 2009/10/15
ジャーナル フリーNaramycinを無条件刺激, 0.0001% Anise Oil, 0.0001%Clove Oilを条件刺激として摂水行動により'におい'の識別能力を調べた.そして前交連前枝や外嗅索を切断し, また嗅球を除去してそれが喫におい'識別能力におよぼす影響をしらべ, これらの神経系が'におい'の識別において果たす役割とその大きさを研究した.
1 無処置正常ラットは約6日間の識別学習によって完全に'におい'の識別が可能となった.'におい'の組合せを変えて学習を反復すると識別条件反応の成立は次第に早くなった.
2 'におい'の識別学習を終えたラットの片側の嗅球を除去すると識別能力は低下するが, 日と共に徐々に回復して22ないし25日後にほぼ完全に回復することが明らかにされた.しかし両側嗅神経系による識別能力を片側だけで完全に代償できないことも分った.また, 嗅球のレベルにおいては'におい'識別に関して左右の優位性はなかった.
3 前交連前枝切断と外嗅索切断は共に'におい'の識別学習の効果を低下させたが, 後者の方が影響が大であった.また切断後の識別能力においても後者の方がより大きい影響を与えた.その点でA.C.Allisonの言うように外嗅索が'におい'のより精密な識別の役割をはたしていると思われる.
4 両側の前交連前枝と外嗅索を全部切断したラット群は, 両側の嗅球を除去した群にくらべ識別学習においても, 切断手術後の識別能力の回復においても, はるかにすぐれていた. これは第3の嗅覚経路の存在を示唆するものである.
5 三叉神経は'におい'の識別に関与するが'におい'識別力全体からみればその役割は小さいと考えられる.抄録全体を表示PDF形式でダウンロード (1781K) -
阿部 政雄1971 年 21 巻 2 号 p. 114-121
発行日: 1971年
公開日: 2009/10/15
ジャーナル フリーAn antitumor agent against Yoshida Sarcoma was produced in rat bone marrow cells which were sensitized in vitro with the medium containing the supernatant fluid of medium of X-irradiated Yoshida sarcoma cells.
From 2, 000R to 4, 000R were optimal doses to release an antigenic cellular agent from irradiated Yoshida Sarcoma cells. And a small amount of serum component was necsesary in culture medium of the tumor cells to obtain the antigenic agent.
Specific activity of antigenic activity was determined between tumor cells and normal tissue cells using C3H/He mouse mammary carcinoma and C3H/He mouse kidney cells.
Lymph node cells sensitized with the tumor cell-antigenic-agent did not inhibit the cell growth of normal kidney cells while inhibit the cell growth of target mouse mammary carcinoma cells.
Effect of sensitized lymph node cells and X-Ray irradiation against tumor growth of C3H/He mouse mammary carcinoma which were inoculated into thigh muscle determined.
The tumors were reduced remarkably when they were treated with sensitized lymph node cells and X-Ray irradiation.抄録全体を表示PDF形式でダウンロード (1129K) -
松本 政雄, 北村 奉正, 菊地 幸江, 尾方 正矩1971 年 21 巻 2 号 p. 132-137
発行日: 1971年
公開日: 2009/10/15
ジャーナル フリーThe authors devised an apparatus to obtain the score indicating ability for the quick motion, in which the response to the optical stimulus done within a certain time limit (300msec or 480 msec) could be indicated as well as the total number of the stimuli.
The five neon lamps which were lighted to give optical stimulus and the five keys to push as the response to the given stimulus were arranged on a board (a lamp and key were assembled in one set).
By employing the above apparatus the score to decide the ability was obtained, which was indicated with the number of responses done within the time limit (300msec) for ten stimuli.
The results were the following :
1. The score distributed in a wide range, and differed in each subject.
2. The score seemed to represent agility of daily movement observed on the subject.
3. The score of the same subject obtained on different day, varied little.
4. The score of the same subject obtained in different times varied little and the training effects seem to be negligible the one 2025 times repetition on the same day, the other for 10 days.抄録全体を表示PDF形式でダウンロード (1004K)
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