In the cases of radiotherapy of cervical cancer of uterus, radiosensitivity of cancer tissue has an important influence on the prognosis and on the selection of the therapeutic method. For radiotherapist, it is very beneficial to interpret radiosensitivity before radiotherapy or on the early time of radiotherapy.
We classified epidermoid carcinoma of cervix into three sub-types, each of which has respectively different radiosensitivity. Three sub-type s are as followed.
Type I : Keratinizing type, high degree of Keratinization.
Type II : Basal cell type, uniform proliferation of spindle cell. Type III : Intermediate type, intermediate disposition between keratinizing type and basal cell type.
As to early time of irradiation, keratinizing type has low radiosensitivity, and basal cell type has high radiosensitivity. Intermediate type has middle radiosensitivity.
Moreover early radiosensitivity correlate with prognosis. Early radiosensitivity could be manifest ed by histological changes observed 6 hours after 400 rad irradiation.

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Endoscopical, histological and autoradiographic studies on gastric type epithelium in the mucosa of duodenal bulb were performed.
Materials were consist of 117 cases ; 84 cases with ulcerative lesion, 9 cases with protruded lesions, 14 cases with no lesion endoscopicaly but with hyperacidity, 10 cases of resected duodenal ulcer. Gastric type epithelium was observed frequently in ulcerative and erosive lesions in the duodenal mucosa even in cases with normo-or hypoacidity.
In autoradiographic studies using ³H-thymidine in ulcerative and erosive lesions, we found results as follows;
1) In early stage, the uptake of tritiated thymidine by the regenerative epithelium covering the base of ulcer was not observed. And labeled cells with ³H-thymidine were located in the glands lying near the base of ulcer. The uptake of tritiated thymidine was not observed in Brunner's glands.
2) At the end of regenerative stage, we found two types of epithelium, intestinal type and gastric type epithlium. ³H-thymidine labeled cells were not observed in gastric type epithelium and located only in the neck regions of the gland as ordinary gastric gland.
Intestinal type epithelium showed the same pattern as ordinary intestinal epithelium.

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Two cases of lung cancer in which the tumor adhesion to the aortic wall was considered on the bronchial angiogram are presented. In these cases, the bronchial angiographic (BAG) findings are as follows : (1) neovascularity along the outer margin of the aorta, (2) neovascularity crossing and encompassing the aorta.
In 1st case, the mediastinal lymphadenopathy with adhesion to the aortic wall in which metastatic lymph nodes could not be torn off the aorta was surgically proven. In 2nd case, although not surgically proven, CT scan demonstrated no radiolucency between the primary lung tumor and the aortic wall. This CT finding is also considered to be equal to the above BAG findings. After completion of radiotherapy, CT revealed that lung mass was disappeared almost completely and that the aortic outline was normally rounded.

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An extremely rare case of primary malignant lymphoma of the parotid gland in a male aged 71 was reported.
According to previous literatures, about 50 cases have been represented by December 1979 although the documentations are not always satisfactory. And only one case has been reported in Japan in 1937.
The patient was admitted in our hospital with a complaint of a swelling of about 3.5×4.0-cm in the left parotid region. No significant findings are seen in physical and laboratory examinations. Radical superficial parotidectomy was performed initially in the diagnosis of mixed tumor clinically and histopathological study revealed non-Hodgkin lymphoma, nodular well differentiated lymphocytic type by Rappaport's classification.
Fifty-one months later, bilateral hilar enlargement and right pulmonary abnormal shadows appeared associated with moderate amounts of right pleural effusion. Besides, on barium study of the stomach a large irregular submucosal mass was thought in the region of the gastric fundus, and then a extragastric lesion was suspected which indicated retroperitoneal lymphadenopathy. Immediately, radiotherapy with chemotherapy using cyclophosphamide and steroid were started by thinking of metastases of the malignant lymphoma. The masses responded very well temporally, but frosted glass-like pulmonary abnormal shadows appeared again which exacerbated progressively, resulting in death with severe dyspnea. He lived for 56 months after his initial diagnosis of malignant lymphoma.
At autopsy, there was no evidence of malignant lymphoma throughout, pathologically. And the pulmonary abnormal shadows were thought to be a result of cyclophosphamide therapy, probably.
In the present case a diagnosis of primary malignant lymphoma of the parotid gland was made on the criteria decided by Hyman and Wolff in 1976.

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The patient was a 70-year-old man who visited our hospital with the chief complaint of hematuria on November 21, 1977. He was performed partial cystectomy for the bladder tumor in 1970. The multiple tumors of the bladder were found on cystoscopy. Biopsy of the bladder showed transitional cell carcinoma, Grade I.
After the paramedian incision the internal iliac artery was exposed extraperitoneally. At the same time, the superior gluteal artery was ligated. The cannula was inserted into the internal iliac artery. 5mg of NK631 was continuously infused via the cannula per day. 120mg of NK631 was infused via the cannula of the right side. After infusion of 60mg of NK631 via the cannula of the left side bleeding of the bladder occured. Infusion was stoped and blood transfusion of 2600ml was undergone. 90mg was medicated via the left cannula in all.
Effects of continuous infusion were judged cystoscopically. The tumors of the right side disappeared or reduced remarkably. But the tumors of the left side were invariable. Side effects of infusion of NK631 were abdominal discomfort and alopetica. Afterward the patient was undergone TUR-Bt and bladder instillation of Adriamycin, Mitomycin C. The recurrence of the tumor has not occured up to the present December, 1979.

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One year and 10 months old boy with XYY syndrome was reported. He was born of a 32 year old mother who had had two normal children previously. Although no clinical abnormality was evident at birth, his development was delayed. He held his head at 6 months and sat alone at 1 year. Although he came to the age of 1 year and 10 months, he could neither walk alone nor speak anything.On physical examination, his weight was 12 kg (+0.4 SD) and his height 88cm (+1.4 SD). He had slightly apathetic facial appearance and brown hair. Neurological examination was normal except for slight muscle hypotonia. Routine laboratory studies were within normal limits. D.Q. scores was 47 by Tsumori and Inage scale for infant developmental test. Chromosome analysis revealed 47, XYY. Growth hormone showed late response after injection of insulin, TRH and LH-RH, but other pituitary hormones showed normal responses. CT scanning revealed low density area in the left temporal tip.
XYY syndrome is characterized by tall stature, aberrant behavior and mild mental subnormality. In 1961 Sandberg et al. reported the first case of XYY syndrome. Since Jacobs et al. reported a high frequency of 47, XYY individuals in penal institutions, an association between the extra Y chromosome and criminal or antisocial behavior was noticed. But in recent wider investigations XYY syndrome was found to be one of the most common chromosome abnormalities in man. And XYY men in normal development were reported. To establish clinical or behavioral characteristics of XYY syndrome, longitudinal prospective studies of XYY infants and children are necessary. It was interesting that this case revealed developmental delay and low density by CT scanning.

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Body computed tomography equipment (GE CT/T X-2) was installated in May, 1979. Data on utilization of body CT were reported. In the initial 8 months, 889 patients were examined. An average of 30 patients were examined per week. Patients from other hospitals for CT scanning were159 and composed 18%. Personnel were 1 radiologist, 1 x-ray technologist and 0.2 nurse on average. The abdomen, pelvis and chest composed 82% of examinations. Most examinations required 10 or more slices. Intravenous contrast material was used more than 50% of the time in these studies. Side effects appeared in 8.9% of patients. One patient with shock stayed one day in ICU department. Only 50% of patients were examined by 7th day after scheduling of CT scanning and 60% by 10th day.

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[in Japanese]

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