The KITAKANTO Medical Journal
Online ISSN : 1883-6135
Print ISSN : 0023-1908
ISSN-L : 0023-1908
Volume 33, Issue 1
Displaying 1-8 of 8 articles from this issue
  • A CASE STUDY IN RURAL COMMUNITIES IN JAVA ISLAND
    SHOSUKE SUZUKI
    1983 Volume 33 Issue 1 Pages 1-10
    Published: March 01, 1983
    Released on J-STAGE: November 11, 2009
    JOURNAL FREE ACCESS
    A holistic approach to human life and health was tried in the three kampung or homesteads, Pasirparahu (P), Slamungkal (S) and Brumbung (B), in Java Island, Indoneisa. P and S are in West Juva, and B is in Central Java. S is in a mountain village of m above the sea level, and the other two are on a plain. Some characteristics of natural environment and cultural background differ between P, S, and B. Home garden, house, water use, daily life, and dietary pattern are described. The methods applied are direct observation, hearing from informants, and measurement for dietary survey and map making. Health check was conducted calling to the total villagers in the three kampung by the author. Body height and weight, and skinfold thickness are smaller than those of Japanese. Blood pressure is, also, smaller and increased little with aging. Male adults eat 1 kg or more of steamed or boiled rice in a day with little animal foods. Ascaris and hookworm infestation in P is more than 50%, and that in B is about 15%. The reason of the difference should be attributable to the way of water use and to the difference in public health activity. Morbidity pattern and the rate show considerable differences between the three kampung.
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  • TAKEAKI NAGAMINE
    1983 Volume 33 Issue 1 Pages 11-28
    Published: March 01, 1983
    Released on J-STAGE: November 11, 2009
    JOURNAL FREE ACCESS
    Seventy five g oral glucose tolerance test (OGTT) has been recently proposed. Little is known, however, on the results by the new test in various liver diseases.
    Studies were conducted with 59 patients with liver diseases : 11 acute viral hepatitis (AVH), 5 chronic inactive hepatitis (CIH), 14 chronic active hepatitis (CAH), 13 liver cirrhosis (LC), 10 fatty liver (FL) and 6 hepatic fibrosis (HF). Eighteen healthy volunteers served as control. Blood samples were taken at 0, 30, 60, 90, 120 and 180 min after oral loading of 75 g glucose, and stored frozen until radioimmunoassay for immunoreactive insulin (IRI) and glucagon (IRG). Blood sugar levels were determined by glucose oxidase method.
    The results obtained herein were as follows :
    (1) None of the patients studied showed fasting blood sugar level more than 140 mg / dl. In contrast, 29 % of CAH, 23 % of LC and 17 % of HF had blood sugar level more than 200 mg / dl at 120 min, indicating the diabetic type (A committee report on the diagnosis of diabetes mellitus, Japan, 1982).
    (2) Exaggerated IRI responses to glucose stimulation were observed in most of the patients with liver diseases, particularly in LC and CAH.
    (3) A significant elevation in the basal IRG level was observed in LC. Circulating IRG levels tended to be suppressed by glucose.
    (4) The mean values of insulinogenic index (Δ IRI / Δ BS, 30 min) appeared to be higher in liver diseases than in diabetes mellitus, as described previously (AVH 2.26, CIH 0.64, CAH 0.81, LC 1.15, FL 1.32, HF 0.65).
    From these observations, it is concluded that approximately 20 % of CAH, LC and HF belongs to the diabetic type, according to 75 g OGTT. The degree of glucose intolerance in patients with liver diseases is relatively mild. However, we should emphasize that serum IRI response to glucose may be useful in the differential diagnosis between glucose intolerance in liver diseases and diabetes mellitus.
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  • SEIICHI HONMA
    1983 Volume 33 Issue 1 Pages 29-41
    Published: March 01, 1983
    Released on J-STAGE: November 11, 2009
    JOURNAL FREE ACCESS
    No significant difference of C.E.A. value was found between primary lung cancer and benign broncho-pulmonary diseases in tissues obtained by transbronchial lung biopsy. Even in the tissue obtained by surgery, C.E.A. values showed also no difference between lung cancer and other lung diseases. However, C.E.A. values in bronchial lavaged fluids were significantly higher in primary lung cancer than that of other lung diseases. Even if C.E.A. values in serum was normal, C.E.A. values in bronchial lavaged fluids was often high in patients of primary lung cancer. These findings suggest that the estimation of C.E.A. values in bronchial lavaged fluids has some supplemental benefit in diagnosis of lung cancer.
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  • YOHICHI TAZAWA
    1983 Volume 33 Issue 1 Pages 43-56
    Published: March 01, 1983
    Released on J-STAGE: November 11, 2009
    JOURNAL FREE ACCESS
    Responses to eight odors of the lateral hypothalamic (LHA) neurons were studied in unanesthetized monkeys. It was proved that LHA neurons have as highly developed ability in odor discrimination as the lateroposterior portion of the orbitofrontal cortex (LPOF). Next, by means of horseradish peroxidase (HRP) and evoked potential methods, olfactory pathways to LHA were studied. Labeled neurons were found mainly in the septum (Spt) and partly in other areas, but scarcely in the prepyriform-amygdaloid areas and olfactory tubercle. Then, olfactory input to Spt area was proved electrophysiologically. Consequently, it was supposed very probable that olfactory impulses come to Spt through the medial olfactory tract directly and / or through the lateral olfactory tract and the olfactory tubercle indirectly, before reaching LHA.
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  • YASUHIRO UCHIYAMA
    1983 Volume 33 Issue 1 Pages 57-68
    Published: March 01, 1983
    Released on J-STAGE: November 11, 2009
    JOURNAL FREE ACCESS
    Systemic scleroderma is a connective tissue disorder characterized by skin sclerosis. This investigation deals with the content and distribution of skin glycosaminoglycan (GAG) in mice with experimentally-induced skin sclerosis. The skin sclerosis was induced either with bis (4-amino-3-methyl-cyclohexyl) methane (BAMM) which is the suspected causative agent of an occupational scleroderma developed in men engaged in the polymerization of epoxy resins or with the scleroderma-inducing GAG isolated from the urine of patietns with systemic scleroderma. Further, the influence of cold temperature on skin change was investigated in BAMM-induced experimental skin sclerosis because cold is related to the occurrence of systemic scleroderma. Skin GAG was isolated from the skin of mice by collagenase-digestion of specimens. The GAG content was determined as the volume of uronic acid and hexosamine. The distribution pattern of skin GAG was determined by the densitometry of alcianophilia of spots developed on cellulose acetate electrophoresis in comparison with that of standard GAGs.
    As a result, dermatan sulfate ratio to total GAG was significantly increased in mice with BAMM-induced skin sclerosis which were maintained in room temperature of 3°C for 12h and temperature of 22°-24°C for the rest time of day or in mice injected with partially purified sclero derma-inducing GAG. This result agrees well with GAG change in the indurative skin of patients with systemic scleroderma. The sclerodermatous skin change further, was observed in a high incidence in mice group with increased skin dermatan sulfate.
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  • MASATO TODA, TOYOJI OKUBO, HIROSHI OSHIMA
    1983 Volume 33 Issue 1 Pages 69-76
    Published: March 01, 1983
    Released on J-STAGE: November 11, 2009
    JOURNAL FREE ACCESS
    According to the serological grouping of temperate phages isolated from clinical isolates, many strains of them were a doubly lysogenic strain carring serotype A and B. Staphylococcus aureus MS3878 was also a doubly lysogenic strain carring serotype A and B. Phages induced from Staphylococcus aureus MS3878 were purified followed by density gradient centrifugation in CsCl, and these phages were used for transduction analysis. The transduction frequency of the nonconjugative drug resistance plasmids rms6 and rms7 with phage serotype A was about 10 -10, but that with phage serotype B was 10 -5 to 10 -7.
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  • MASUHIRO KATO, MATSUHISA INOUE
    1983 Volume 33 Issue 1 Pages 77-83
    Published: March 01, 1983
    Released on J-STAGE: November 11, 2009
    JOURNAL FREE ACCESS
    We performed the genetic analysis of non-conjugative single sulfanilamide (Su) -resistant gene (s) on gram-nagative bacteria. Almost all of the strains with non-conjugative Su restance carried nonconjugative Su plasmid, pSu. The molecular weight of most non-conjugative pSu plasmids ranged from 3.7 to 3.8 Md. pSu, except one, is mostly due to the formation of Su-resistant dihydropteroate synthetase (DHPS). From the transformation analysis, pSu plasmids were not restricted by Echerichia coli K12 restriction endonuclease system. Also DNA replication of the pSu plasmids required DNA polymerase 1. In addition, the pSu plasmid can be amplified in the presence of chloramphenicol. However, pSu plasmids are compatible with another multiple plasmids.
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  • IN FORTEEN CASES OF A.S.O.
    MASAMICHI KAWABE, MORITO KATO, TESTUO IIJIMA, TESTUO AXZAI
    1983 Volume 33 Issue 1 Pages 85-90
    Published: March 01, 1983
    Released on J-STAGE: November 11, 2009
    JOURNAL FREE ACCESS
    Since 1980, we performed the aorto-iliac and / or femoral, and femoro-popliteal bypass surgeries in 14 cases of A.S.O. (arterio sclerosis obliterans).
    The rate of patency was 92% (13 / 14). Bypass graft was occluded in only one case. Operations should be done immediately after angiography, because rapid obstructive process was seen in this case.
    U.K. (urokinase) used immidiatly after operation was very effective to prevent thrombosis and to preserve patency of the grafts.
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