The Kurume Medical Journal
Online ISSN : 1881-2090
Print ISSN : 0023-5679
ISSN-L : 0023-5679
1 巻, 1 号
選択された号の論文の10件中1~10を表示しています
  • V. ON THE MECHANISM OF THE FORMATION OF VITAMIN C FROM 2-KETOGULONIC ACID METHYLESTER
    KEISUKE YASHIMA
    1954 年 1 巻 1 号 p. 1-10
    発行日: 1954/03/01
    公開日: 2009/08/11
    ジャーナル フリー
    The author has already reported that 2-ketogulonic acid methylester (KGM) has an antiscorbutic action and, in the presence of the extract from plant and animal tissues, SH-compounds, barbituric acid derivatives etc., turn into a Vitamin C-like substance, which, in the author's opinion, is decided as ascorbic acid (AsA) (1-4). If so, what sort of mechanism is at work for the formation of Vitamin C from KGM ? Is the Vitamin C produced directly by enolisation and lactonisation from KGM which may take place ? Or might it be assumed that Vitamin C is formed through some intermediary produced from KGM ? Sasamoto (5) has demonstrated that Vitamin C was produced from mannose via 2, 3-diketogulonic acid (DGA), while Suda (6) verified an increase in the reduction value of indophenol by incubating DGA with liver paste prepared from rabbits or white rats. Sasamoto and Beppu (7), on the other hand, proved this increased reduction value to be the real value of Vitamin C and demonstrated the possibility of the formation of AsA from DGA in vivo. Having been interested in the mechanism for the formation of Vitamin C from KGM, the author has tried the following experiments with a view to throwing some light on the problem.
  • HIROSHI SHIBUE
    1954 年 1 巻 1 号 p. 11-18
    発行日: 1954/03/01
    公開日: 2009/08/11
    ジャーナル フリー
    Two kinds of fresh-water shrimps, Neocaridina denticulata (de Haan) and Leander paucidens (de Haan), were identified as new second intermediate hosts of Phyllodistomum macrobrachicola Yamaguti, 1934. The author wishes to express his hearty thanks to Prof. Dr. K. Okabe who kindly directed this study.
  • YASUZÔ KOGA
    1954 年 1 巻 1 号 p. 19-25
    発行日: 1954/03/01
    公開日: 2009/08/11
    ジャーナル フリー
    In autumn of 1952, the author found a new species of encysted metacercaria in the nymphs of the stone flies collected from the rivers in Hita City, Ôita Prefecture, and in Kurume City, Fukuoka Prefecture. Some rats and a dog were given this new metacercaria experimentally and adult trematodes of a new species belonging to the family Lecithodendriidae were obtained from the small intestines of those experimental animals.
  • ESPECIALLY ON THE NEW CLASSIFICATION OF HUMAN TYPE O SALIVA BY PRECIPITIN REACTION.
    KATUZO INOUE
    1954 年 1 巻 1 号 p. 26-33
    発行日: 1954/03/01
    公開日: 2009/08/11
    ジャーナル フリー
    Remarkable studies on O substance have been reported by many workers : Hooker and Anderson (1921), Witebsky (1927), Yamasaki (1933), Fukao (1937), Schiff (1927), and Miyazaki (1930). Eisler (1930) confirmed anti dysentery bacilli goat serum agglutinated human blood cells, and Kagaya (1937) found that in red blood cells of white rat, rabbit, pig, dog, sheep, and cat and in kidney of guinea pig and horse, there was a common antigen to human O type blood cells-the third heterogen antigen. Inoue (1943) devided O substance into three parts, i.e. OI, OII and OIII, by agglutinin reaction with sera, of sheep and domestic fowl immunized with human O type blood cells, dysentery bacilli, blood cells of rabbit and white rat, and kidney of guinea pig. This finding was confirmed later by Yamaguchi (1943) and Nakano (1951). Ôta and Oka (1952) and Sakimura (1952) studied on A and B substances in human saliva, and Watanabe (1952) on secretive condition of partial antigens of O substance in human saliva by precipitin reaction and classified human O type saliva not only in usual secretive and nonsecretive types but in the more detailed types. The present investigation was designated to make clear the secretive condition of partial antigens of O substance, by analysing the partial antigens of human O type saliva using the partial antibodies prepared by absorption.
  • YOSHIHIKO ZINNAI
    1954 年 1 巻 1 号 p. 34-41
    発行日: 1954/03/01
    公開日: 2009/08/11
    ジャーナル フリー
    Since 1927 O substance has been investigated by many workers (Hooker and Anderson (1), Witebsky (2), Yamasaki (3) and so on) and noticeable studies have been reported. In 1937 Inoue (4) succeeded to devide O substance antigenically into three parts, i. e. OI, OII and OIII by means of agglutinin reaction with sheep and domestic fowl immune sera, prepared by immunizing the animals with human O type blood cells, Shiga dysentery bacilli, blood cells of rabbit and white rat, and kidney of guinea pig. Later, Watanabe (5) could analyse partial antigens of O substance by precipitin reaction. Shirai (6) reported by homogenous hemagglutination inhibition test that type substance was also contained in human sperm. In 1937 Katsuya (7) confirmed for the first time the presence of type precipitinogens in sperm using precipitin reaction. Fukao and his co-workers (8) found that human sperm as well as human saliva could be classified in secretive and non-secretive types. Watanabe (5) suggested that human O type saliva would be devided into more detailed types than usual secretive and non-secretive types, as he proved the presence of partial antigens in human O type saliva by precipitin reaction. The present investigation was conducted to find secretive condition of partial antigens of human O type sperm by means of precipitin reaction between sperm and partial antibodies of O substance.
  • YOSHIO YOSHIZUMI, TOSHIO IMANARI
    1954 年 1 巻 1 号 p. 42-48
    発行日: 1954/03/01
    公開日: 2009/08/11
    ジャーナル フリー
    Hypertonic glucose solution injected into the lower portion of the thoracic aorta brought about a marked elevation of liver function. The result appeared to indicate that penicillin or a sulfaminide drug would prove more infallibly effective when injected in glucose solution into the aorta than when otherwise administered and that intra-aortic injection of a mixture of hypertonic glucose solution and penicillin or a sulfaminide drug would be a very reasonable therapy for the liver, gall-bladder, etc, with purulent diseases. On this assumption a mixture of hypertonic glucose solution and penicillin or a sulfaminide drug was injected into the lower portion or the thoracic aorta in purulent diseases of the liver and gall-bladder. The result was excellent and fever inreducible by any other drug therapy was often reduced instantaneously by this therapy. Even in cases in which this therapy fails to bring about a complete cure, a condition safe for surgical treatment will be induced by eliminating acute inflammation by this therapy.
  • TOHOSHI YANO
    1954 年 1 巻 1 号 p. 49-60
    発行日: 1954/03/01
    公開日: 2009/08/11
    ジャーナル フリー
    An error in the evaluation of sedimentation rate arising from a wrong technique or want of an adequate consideration of climatic and other conditions may often lead to a mistaken idea of the sedimentation rate peculiar to the disease and consequently to a wrong prognosis as to its progress. The author's experiments on this subject, started in October 1947 and continued up to the present, have disclosed an interesting fact that the clinical value of sedimentation rate is enhanced by a comparative study of the sedimentation reaction (abbreviated S.R. below) of arterial blood and that of venous blood. The S.R. of arterial blood has hitherto attracted little attention and there are only a few reports on the subject. This is why the author dares to present his data obtained in a very limited number of cases.
  • I. PURIFICATION BY MEANS OF VARIOUS ADSORBENTS AND PRECIPITANTS.
    YOH NAKAGAWA, AKIO AKASHI
    1954 年 1 巻 1 号 p. 61-66
    発行日: 1954/03/01
    公開日: 2009/08/11
    ジャーナル フリー
    It has been well known that differential centrifugation by the use of ultracentrifuge is the most effective method for the purification of animal viruses. However, as the use of ultracentrifuge is so far fairly limited in this country, other methods for partially purifying viruses should be investigated more in detail. Adsorption and elution of viruses by means of adsorbents have been attempted by numerous workers for the partial purification of viruses. As adsorbents, resins (1) (2), clay (3), kaolin (4) (5) (6) as well as chicken red blood cells (7) (8) (9), in the case of viruses having hemagglutinins, have been employed. In recent years it has been shown that methyl alcohol at low temperature precipitates various proteins as well as viruses without denature or inactivation. And this fact has found wide application in the purification of various viruses (10) (11) (12) (13). The present work deals with the purification of influenza virus by methods in which adsorbents and precipitants are used or combined.
  • KOKI ABE, KUNIO YANO
    1954 年 1 巻 1 号 p. 67-70
    発行日: 1954/03/01
    公開日: 2009/08/11
    ジャーナル フリー
  • KUNIO YANO
    1954 年 1 巻 1 号 p. 71-84
    発行日: 1954/03/01
    公開日: 2009/08/11
    ジャーナル フリー
    One important conclusion to be drawn from the foregoing results put together is: Prior to the age of 5 or 6 the blind and deaf taken as a group are not notably different from the normal in the average level of growth or the standard deviation. Later, however, the average level of growth rises higher for the latter than for the former as they advance in age, the difference reaching the maximum at 18 or 19 (ages at which the process) of growth is brought nearly to a close, while the standard deviation becomes greater with age for some time former than for the latter, the ratio culminating at about 14 or 15 in males and about 12 in females and then declining till it converges to 1, i.e., it becomes equal for the former and the latter group, at 18 or 19. This seems an important fact to be noted in all special-school education, because a widely varied distribution of the period of growth in children makes uniform education very difficult in these schools. A class formed by age, for instance, will naturally be a promiscuous mixture of children for different in the level of growth. Such in convenience is to be met with to some extent in schools for normal children, but it is incomparably greater in special schools, according to the author's own educational experience with physically handicapped children. It is therefore desirous that some adequate measures be taken for these children from a more reasonable point of view.
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