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Volume 10, Issue 1
Displaying 1-6 of 6 articles from this issue
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II. THE FACTORS INFLUENCING THE PHAGOCYTOSIS OF MYCOBACTERIA BY L CELLS, ESPECIALLY THE EFFECTS OF OLD TUBERCULIN TREATMENT TO THE CELLSHIROYUKI SHIKATA, MASAHIRO NAKAMURA1963 Volume 10 Issue 1 Pages 1-11
Published: March 15, 1963
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe host-parasite relationship involving many factors is easily understood by observing a simple infection system from which the involved factors are possibly excluded. Furthermore, it is possible to study each role of the factors influencing the infection by utilizing the thus simplified infection system. It would be expected that, in the host-parasite relationship, the factors in the liquid component existing between the host and parasite might play important roles in susceptibility of the host against the parasites and in the completion of infection. The authors (1) investigated the effects of the sera on the phagocytosis in the course of cellmycobacteria infection system by using the L cell which was derived from mouse fibroblast.This present paper is to report the effect of old tuberculin of BCG on the course of infection of BCG to the L cell because it is conceivable that the effects of metabolates of the parasites on the phagocytosis or invasion to the cell are important.View full abstractDownload PDF (987K) -
YOSHIE UENO, YUTAKA MITSUFUJI, FUMIO OSHIMA, MASAHITO HIGUCHI, MASAHIR ...1963 Volume 10 Issue 1 Pages 12-20
Published: March 15, 1963
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSIn the previous paper (1), a method of isolation of Myc. lepraemurium from infected tissue by means of trypsin digestion prior to the procedure of Hanks' method (2) was described. It is fact, however, that contamination of the tissue component in the final product obtained can not be avoided even through careful procedure. This method has two additional disadvantages; a small yield of the bacilli and it is a complicated procedure.The present paper reports a new and simple isolation and purification method of Myc. lepraemurium, under sterile conditions, from the subcutaneous lepromata of the rat by using trypsin digestion with sodium desoxycholate treatment. The efficiency of this method was determined by observing Ziehl-Neelsen staining, Ziehl Nile blue staining (3) under a light microscope, and electron micrographes. Some enzymatic activities and the remaining infectivity of the final product as compared to that of the starting material were also observed.View full abstractDownload PDF (6627K) -
HIROSHI MUKASA, KAZUTOYO INANAGA1963 Volume 10 Issue 1 Pages 21-28
Published: March 15, 1963
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSAlthough chlorpromazine is one of the psychotherapeutic drugs used widely, its therapeutic effects have been inadequately correlated with its physiological response pattern. The authors and their co-workers have observed the effects of psychotherapeutic drugs on the EEG and minor tremor (MT) for the past several years, noticing that there exists a definite relation between the clinical and MT response pattern. The purpose of this article is to investigate whether a relation exists between the clinical and physiological responses to chlorpromazine, as indicated by EEG and MT.View full abstractDownload PDF (580K) -
KAZUTOYO INANAGA, HIROSHI MUKASA1963 Volume 10 Issue 1 Pages 29-36
Published: March 15, 1963
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe lid vibration test is generally used as a procedure measuring the motor function of the facial nerve, and exaggerated lid vibration has been considered as an expression of general nervous hyperirritability. However, it has never been subjected to datailed neurophysiological study.The authors have been studying the fine tremor on the body surface, which was called minor tremor by the authors and microvibration by Rohracher.In this report, the photopalpebral responses provoked by intermittent photic stimulation were observed in some neurological diseases by the same technique employed for the study of minor tremor.View full abstractDownload PDF (5598K) -
MUTSUYA TAKEUCHI, YUKIO TANAKA1963 Volume 10 Issue 1 Pages 37-50
Published: March 15, 1963
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSIn a previous paper (1960) the authors reported that a mixture of equal quantities of hexosamine and hexuronic acid was most effective for preventing the occurrence of experimental hepatic cancer of rat induced by oral administration of p-dimethylaminoazobenzene (DAB), compared to mixtures of another component of acid mucopolysaccharide (AMPS). The fact has thereafter made the authors interested in relationship between cancer and AMPS. On the other hand, it is presumed that AMPS is always found in the inflammatory focus of the injured tissue perhaps as a defense responses of the body and is possible to combine with basic substances as histamine and peptide produced by the abnormal breakdown of inflammatory tissue protein. These may suggest that AMPS not only compose the substrate of connective tissue but also has a role of preventing the growth of canceric tissues or neutrizing toxic substances produced by malignant tissue elements.Thus, an attempt was made in this paper to examine such possibilities by investigating detailed properties of each AMPS fraction (hyaluronic acid, chondroitin sulfuric acid, heparin and the like), of constituents soluble in physiologic saline solution, and of serum protein fractions, esp. the basic fractions, found in the tissue and blood of human well as experimental cancer.View full abstractDownload PDF (1446K) -
MORPHOLOGY OF LIVER : PART IHIROSHI TSUTSUMI, AKIRA WATANABE, TOSHIRO NAKASHIMA1963 Volume 10 Issue 1 Pages 51-60
Published: March 15, 1963
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe basin of the River Chikugo around Kurume is still one of the prominent areas in Japan infected with schistosomiasis japonica. Therefore, autopsies done in this district often reveal schistosome ova in the tissue specimens of each organ. Furthermore, as a residue of the present disease, very high pathological changes of the liver, advancing to a stage of liver cirrhosis with schistosomal ova, can be detected.During the seven years from 1955-1961 the authors found the ova of schistosoma japonicum in 34 cases of all the liver specimens prepared in their department. In this first report, macroscopical observations on the morphology of liver are described. Full particulars will be published later by Watanabe.View full abstractDownload PDF (10392K)
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