For living cell membrane, a stable dynamic ionic state across the membrane is required in order to maintain the intracellular electrical neutrality, Gibbs-Donnan's equilibration and the balance of osmotic pressure. When the outflux of K ions is discussed from these points of view, the potential gradient, the concentration gradient of K and the hydrodynamic pressure are assumed as the driving forces. Moreover, it is currently considered that K
+ efflux is passively controlled by the potential gradient which is a mirror of the concentration difference of K
+. However, the present author (1, 2) obtained experimental results which contradict this conception.In this paper, the investigation of the ionic interrelationship between K
+ outflux and external sodium ions has been attempted in order to determine the detail of the passive outward movement of K ions.
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