The Kurume Medical Journal
Online ISSN : 1881-2090
Print ISSN : 0023-5679
ISSN-L : 0023-5679
Volume 10, Issue 3
Displaying 1-10 of 10 articles from this issue
  • IKUICHIRO HIROTO
    1963 Volume 10 Issue 3 Pages 129-136
    Published: September 30, 1963
    Released on J-STAGE: August 11, 2009
    JOURNAL FREE ACCESS
    The cervical lymphatic system consists of : (1) the deep cervical lymphatic system along the jugular vein : (2) the superficial cervical lymphatic system along the accessory nerve : and (3) the paratracheal lymphatic system along the recurrent laryngeal nerve. The aim of the neck dissection is, as a matter of course, to excise completely these cervical nodes which already have had or may possibly come to have metastasis, for the removal of carcinoma.The routine technique of the neck dissection is the excision en bloc of the deep cervical and the superficial lymphatic nodes together with their adjacent tissues : the paratracheal lymphatic nodes seem not to be included in this range of excision. This is because of the lower incidence of metastasis in the paratracheal nodes. However, in some cases, it may be contract to the aim of neck dissection. Then, in what situations should the paratracheal nodes be excised? This problem is the main theme of the present paper.
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  • MAKOTO KURATA
    1963 Volume 10 Issue 3 Pages 137-161
    Published: September 30, 1963
    Released on J-STAGE: August 11, 2009
    JOURNAL FREE ACCESS
    Schistosomiasis japonica is an endemic disease found mainly in Japan, Formosa, Central and South China, the Philippines and Celebes. Studies conducted by Fujii (1847), Katsurada (1904), Miyairi (1914), Fujinami, Miyagawa, Tsuchiya, Faust and Meleney and others have determined the parasites, the intermediate hosts and the clinical and pathological features of this disease. A number of subsequent investigators have made contributions toward further clarification of the parasitosis. In more recent years, a considerable number of informations, especially, clinicopathological aspects of the disease have been added. Since this university hospital is located in one of the endemic areas, we often come across patients of schistomiasis. The present paper deals with several recent investigations which were carried out on patients and also on animals experimentally infected with Schistosoma japonicum.
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  • IKUICHIRO HIROTO
    1963 Volume 10 Issue 3 Pages 162-172
    Published: September 30, 1963
    Released on J-STAGE: August 11, 2009
    JOURNAL FREE ACCESS
    The surgical treatment of cancer in the hypopharynx and cervical esophagus consists in 1) cervical esophagectomy or total pharyngoesophagectomy with conservation of the larynx, 2) pharyngolaryngectomy, 3) pharyngolaryngoesophagectomy, 4) subtotal esophagectomy and cervical esophagogastrostomy. They are either associated with radiotherapy or not. Prognostic study of 56 cases who came under the author's surgical care disclosed that 2 cases of cervical esophagectomy all died within 1.5 years, 3 cases of pharyngolaryngectomy also all died in less than 2 years, and survival over 5 years was only found among 51 cases of pharyngolaryngoesophagectomy. The pharyngolaryngoesophagectomy should be emphasized as a worthwhile surgery without thoracotomy for hypopharyngoesophageal carcinoma, even if the larynx is not yet involved. Therefore, this report mainly discusses pharyngolaryngoesophagectomy from the surgical point of view.
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  • IKUICHIRO HIROTO, TATSUMI IZAWA
    1963 Volume 10 Issue 3 Pages 173-186
    Published: September 30, 1963
    Released on J-STAGE: August 11, 2009
    JOURNAL FREE ACCESS
    It is well known that, in carcinoma in otorhinolaryngological field, metastases are histologically recognized at high rates in the swollen regional lymph nodes, especially in the cases of pharyngeal and laryngeal carcinomas. In maxillary carcinoma, however, there are many cases in which no metastasis are found histologically in the cervical glands, even if they are swollen. Microscopic metastases are demonstrated only when maxillary carcinoma extends to the nasal cavity from the maxillary sinus or when the cancer is treated by surgery. There are two theories as to the mechanism of this metastasis; it is due to 1) anatomical characteristic of maxillary sinus and 2) some stimulations such as inflammation.The present communication reports our fundamental studies which aimed at elucidating factors stimulating metastasis and in which the changes in the lymph were studied under various conditions in rabbits after inplantation of Brown-Pearce cancer.
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  • KENICHI NODA
    1963 Volume 10 Issue 3 Pages 187-191
    Published: September 30, 1963
    Released on J-STAGE: August 11, 2009
    JOURNAL FREE ACCESS
    For living cell membrane, a stable dynamic ionic state across the membrane is required in order to maintain the intracellular electrical neutrality, Gibbs-Donnan's equilibration and the balance of osmotic pressure. When the outflux of K ions is discussed from these points of view, the potential gradient, the concentration gradient of K and the hydrodynamic pressure are assumed as the driving forces. Moreover, it is currently considered that K+ efflux is passively controlled by the potential gradient which is a mirror of the concentration difference of K+. However, the present author (1, 2) obtained experimental results which contradict this conception.In this paper, the investigation of the ionic interrelationship between K+ outflux and external sodium ions has been attempted in order to determine the detail of the passive outward movement of K ions.
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  • TATSUO MORITA, MUTSUYA TAKEUCHI
    1963 Volume 10 Issue 3 Pages 192-206
    Published: September 30, 1963
    Released on J-STAGE: August 11, 2009
    JOURNAL FREE ACCESS
    It is well established that disturbed connective tissue formation or delayed wound healing found in scorbutic guinea pig which has no ability to synthetize 1-ascorbic acid (vitamin C) in the body, is easily improved or cured by oral or subcutaneous administration of vitamin C. Recently Gould who has postulated a direct effect of 1-ascorbic acid on the collagen formation by employing the polyvinyl sponge insertion method, pointed out that the direct injection of vitamin C into the granulation formed around the sponge inserted into the skin was more effective in increasing collagen formation of the focus in guinea pigs with scurvy than any other method of vitamin C administration, such as oral, subcutaneous, etc. The mechanism by which vitamin C enhances collagen formation, however, is still poorly understood.It is presently accepted that the sponge method and carrageenin granuloma are useful for the biochemical study of connective tissue formation. Kimoto et al. and Mizuochi examined the chemical properties of connective tissue of experimental rat granuloma induced by sodium alginate in place of carrageenin, since the former is not only easily separated from the surrounding tissues but also a sufficient amount of specimen can be obtained for chemical determination as well as for histological observation.By using Kimot's alginate granuloma the authors examined biochemically and histologically the effect of vitamin C on the connective tissue formation in order to elucidate the role of this vitamin in the animal with and without ability to biosyn thetize 1-ascorbic acid. The present paper involves the chemical results of this study which measured the amount of hydroxyproline which is a specific component of collagen fiber and which increases in parallel with fibers formation, and assayed hexosamine, an indispensable component of mucopolysaccharide which constitutes the intercellular substance of connective tissue. The histrogical results will be published elsewhere.
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  • MASAHISA SHINGU, SHIGERU YAMAMOTO, KENJI KURODA
    1963 Volume 10 Issue 3 Pages 207-213
    Published: September 30, 1963
    Released on J-STAGE: August 11, 2009
    JOURNAL FREE ACCESS
    The virulent tests on polioviruses not only afford the important means for investigating their variation and heredity, but especially need examination of the recovery of virulence which might possibly be brought about by passing through the human body. The virulence test using monkeys has been widely recognized as the best method, but it is followed by economic and technical difficulties. In order to eliminate such difficulties, several methods have been proposed for the in vitro marker test.The present paper deals with a new in vitro method for virulence tests on polioviruses by using the primary human amnion cell, with the result of intraspinal injection of polioviruses into mice.
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  • TAKEO OKANO, HIROJI ESAKI, YOSHIMARO MIYAZAKI, TAKUSHI FUJITA, HIDEO O ...
    1963 Volume 10 Issue 3 Pages 214-224
    Published: September 30, 1963
    Released on J-STAGE: August 11, 2009
    JOURNAL FREE ACCESS
    The authors previously reported in Part I the effect of salt water intake on the growth of rat. In this paper, the effect of salt water intake on the blood pressure of rat is reported.
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  • SOJI MATSUFUJI, MASAO FUKUDA, SHIGEHISA NAKAMURA
    1963 Volume 10 Issue 3 Pages 225-231
    Published: September 30, 1963
    Released on J-STAGE: August 11, 2009
    JOURNAL FREE ACCESS
    Contrary to other infectius diseases, the antibody production in vivo is very low in candidiasis. Healthy individuals harbor Candida albicans saprophytically, and therefore has serologically less specificity.As an immune reaction for Candida, agglutination test has generally been used. However, it tends to give a spontaneous agglutination. It is slso known that a cross agglutination would occur between Candida and bacteria strains or among Candida strains themselves. Akiba and Ata reported that a cross reaction was observed between Candida albicans and Mycobacterium tuberculosis. A series of experiments was therefore carried out to study a common antigen for tubercle bacillus and Candida albicans.
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  • TAKESUKE MUTEKI, KAZUHIRO KAWABE, KANZI HIROHASHI, MASAYA NISHIMURA
    1963 Volume 10 Issue 3 Pages 232-240
    Published: September 30, 1963
    Released on J-STAGE: August 11, 2009
    JOURNAL FREE ACCESS
    Anesthetic technique for open cardiac surgery has been discussed from various viewpoints. However, anesthetic management during cardio-pulmonary bypass provide many problems for discussion since the bubble oxygenator is efficient in removing volatile anesthetics, and the concentration of any circulating non-volatile drugs is diluted by the addition of the blood volume of the pump to the blood volume of the patient. If no anesthetic agent is added to the oxygenator system, the patient tends to awake during the period of bypass.The authors have especially considered the obtainment of a complete quiet surgical field during bypass by use of hypothermia and muscle relaxants.This is a clinical report on the use of Mylaxen (Hexa-fluorenium bromide) for the maintenance of apnea during open cardiac operation using extracorporeal circulation as compared with the use of two other muscle relaxants, Imbretil, and D-tubocurarine.
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