The Kurume Medical Journal
Online ISSN : 1881-2090
Print ISSN : 0023-5679
ISSN-L : 0023-5679
22 巻, 4 号
選択された号の論文の10件中1~10を表示しています
  • HIROSHI MASUDA, SHIGEKI SHICHIJO, HIROSHI IMAI, MUTSUYA TAKEUCHI
    1975 年 22 巻 4 号 p. 199-204
    発行日: 1976/03/25
    公開日: 2010/02/08
    ジャーナル フリー
    A rapid method is described for the chemical determination of keratan sulfate in patient's urine with mucopolysaccharidosis IV (Morquio syndrome). The method of estimation of the glycosaminoglycan relies upon its resistance to enzymic degradation, and involves cellulose acetate-strip electrophoresis. This quantitative method can be carried out in a few days and provides means of a chemical diagnosis of mucopolysaccharidosis IV (Morquio syndrome) in the clinical laboratory. Keratan sulfate/heparan sulfate ratio was 15.8 in this type, while it was 1.5±0.67 in normal, 0.3 in mucopolysaccharidosis I and 0.4 in mucopolysaccharidosis II, respectively.
  • I. ANTIGENIC PROPERTIES
    SHIGERU YAMAMOTO, HIDEFUMI KABUTA, KUMAO NISHIYAMA, HIROSHI WAKISAKA
    1975 年 22 巻 4 号 p. 205-217
    発行日: 1976/03/25
    公開日: 2010/02/08
    ジャーナル フリー
    One recombinant virus was obtained from a cross between herpes simplex virus type 1 and 2 which was neutralized well by both antisera to parent viruses. Reciprocal neutralization kinetic studies on the recombinant revealed that it was neutralized more rapidly than homologous viruses by any antiserum not only to parent viruses but also to the other type 1 and 2 strains examined. Conversely, the antiserum to the recombinant could neutralize only very slowly the other virus strains including parents. Such the characteristics and heat lability of the “new” virus suggests that the surface of the virion consists of antigenically mosaic structure mixed with various components which build up the antigenic structures of type 1 and 2.
  • MASAHIRO NAKAMURA, TOHRU ITOH, NAOKO HIRATA
    1975 年 22 巻 4 号 p. 219-221
    発行日: 1976/03/25
    公開日: 2010/02/08
    ジャーナル フリー
    A phenomenon that the growth of mycoplasma is inhibited by chloroform-inactivated mycoplasmas was described. The characteristics of the substance is not clear yet, but there is a possible method for subclassif ication of mycoplasmas which are classified by other routine methods, for instance antiserum growth inhibition, polyacrylamide gel diffusion, and so on.
  • MASANOBU URABE, SETSUHARU FUJITA, KOICHIRO TAKASAKI
    1975 年 22 巻 4 号 p. 223-230
    発行日: 1976/03/25
    公開日: 2010/02/08
    ジャーナル フリー
    Effects of d-methamphetamine and tyramine were studied on several physiological parameters in isolated rat heart muscle preparations. The sinoatrial rate and electrically-induced ventricular contractile force were suppressed dose-dependently by methamphetamine, although both the activities of cardiac muscle were effectively enhanced by tyramine. Clear-cut differences between the two amines were also demonstrated in their effect on ventricular excitability and functional refractoriness. Methamphetamine caused depressed excitability and increased refractoriness of cardiac muscle, whereas tyramine produced no change in its excitability, rather causing decreased refractoriness. It could be suggested from these results that methamphetamine is a direct cardiodepressant rather than a cardiac stimulant. In view of the structure-activity relationship, the direct cardiodepressant effect of methamphetamine was presumed to be basically related to so-called direct membrane effect.
  • KATSUYOSHI MAEDA
    1975 年 22 巻 4 号 p. 231-239
    発行日: 1976/03/25
    公開日: 2010/02/08
    ジャーナル フリー
    A fact-finding survey on Occupational Cervicobrachial Disorder in an assembly plant is described. In this plant, amplifiers of stereophonic sound system were assembled on the conveyor lines. About 90 workwomen were engaged in the lines and majority of them repeatedly used the arms and hands with the posture being restrained to the lines. 25 workwomen aged 18 - 30 who complained of stiffness and pain over the shoulder and neck etc. were examined. And working conditions were analysed from the viewpoint of industrial health. Occupational Cervicobrachial Disorder had been considered to be peculiar to business machine operators. But as a result of this survey, it was made clear that Occupational Cervicobrachial Disorder was not peculiar to business machine operators and might develop in assembly plant workers in bad working conditions.
  • KIROKU OHISHI, SHOJI TOKUNAGA, MICHIYASU NONAKA, MICHIHIRO KOGA
    1975 年 22 巻 4 号 p. 241-245
    発行日: 1976/03/25
    公開日: 2010/02/08
    ジャーナル フリー
    Among acquired valve diseases, surgical results are not quite satisfactory in combined valve diseases with tricuspid insufficiency. We classified tricuspid insufficiency into three grades depending on the degree of regurgitation through the tricuspid valve and surgical results including hemodynamic changes after surgery and prognosis were studied from the point of relation to the degree of regurgitation.
  • I. CORROSION CASTING METHOD OF RENAL BLOOD VESSELS FOR SCANNING ELECTRON MICROSCOPY
    SHINSHI NODA, TAKATO KAWADA, NOBUYUKI MIYOSHI, KOSAKU ETO
    1975 年 22 巻 4 号 p. 247-251
    発行日: 1976/03/25
    公開日: 2010/02/08
    ジャーナル フリー
    The method to prepare reno-vascular castings for scanning electron microscopy was described. This new devised method, a frozen cracking of the vascular casts following resin injection, made it possible to observe easily and distinctly the normal renal microcirculation including pentubular and glomerular capillary architecture.
  • HIDEKI KOJIMA
    1975 年 22 巻 4 号 p. 253-260
    発行日: 1976/03/25
    公開日: 2010/02/08
    ジャーナル フリー
    The formaldehyde induced fluorescence microscopy was applied to bullfrog sympathetic ganglia in order to clarify the cellular localization of catecholamines. The distinctly different two types of cells (small cells showing an extremely bright yellow fluorescence and ordinary ganglion cells showing a green to yellow-green fluorescence) were observed in sections of sympathetic ganglia treated with formaldehyde vapour of 75% humidity equilibration at 80°C for 1 hour. Small cells often formed clusters of several cells, and were located near blood vessels. Treatment with formaldehye vapour of 90% humidity equilibration for 2 hours at 80°C caused diffusion of the fluorescent material in two different cell types. An extremely bright yellow fluorescence was found to be intensified when treated with optimum formaldehyde vapour either at 80°C for 15 min or 50°C for 30 min, whereas a green to yellow-green fluorescence was most intense under the condition of formaldehyde vapour at 80°C for 3 hours.Thus, it may be concluded that the small cell cluster contains a primary catecholamine (dopamine or noradrenaline) and that the ganglion cell contains mainly a secondary catecholamine (adrenaline).
  • SHINSHI NODA, KOSAKU ETO
    1975 年 22 巻 4 号 p. 261-268
    発行日: 1976/03/25
    公開日: 2010/02/08
    ジャーナル フリー
    Some interesting results were obtained by light- and electron microscopic investigation of human prostate cancer cellls. There were the f ilamentous structures with the diameter of 450-500 Å and the length less than 3.6 μ and the filled globular particles of which interspace was 10 Å and arrangement was like crystal. The diameter of the globular particles was similar to that of the filamentous structure. This type of particle is supposed to have certain correlation to papova virus group which is a DNA virus, when viewed from its shape or structure.
  • KAZUOKI YOKOCHI, HIROHISA KATO, SHIGEYUKI KOIKE, CHIHEI TANAKA, YUSHI ...
    1975 年 22 巻 4 号 p. 269-278
    発行日: 1976/03/25
    公開日: 2010/02/08
    ジャーナル フリー
    Echocardiograms were recorded in 35 neonates with congenital heart disease who had respiratory distress, severe cyanosis or heart murmur in early neonatal period, 5 physically normal newborn infants and 4 with idiopathic respiratory distress syndrome.Examinations were performed to detect the relationship between the aorta and the pulmonary artery, the tricuspid valve and the Ynitral valve, and the continuity between the atrio-ventricular valve and the semilunar valve and the presence of the ventricular or the atrial septum by a sector scanning method of the echocardiography, and in almost all cases an accurate diagnosis was made before the cardiac catheterization.We were convinced that the echocardiographic technique was available to identify these structural abnormalities and to recognize the relationship of the great vessels and those of the atrio-ventricular valves. Since this new technique is rapid and noninvasive, this method should be indicated for the neonate with severe cardio-pulmonary syndrome to diagnose the accurate cardiac anomalies or to differentiate from other lesions.
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