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Volume 26, Issue 3
Displaying 1-13 of 13 articles from this issue
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HANS POPPER, LOUIS B. THOMAS1979 Volume 26 Issue 3 Pages 189-204
Published: October 15, 1979
Released on J-STAGE: August 11, 2009
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WATARU MORI1979 Volume 26 Issue 3 Pages 205-213
Published: October 15, 1979
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSAn immunological method for human hemoglobin assay was established, using which contents of fetal hemoglobin in the blood of hepatocellular carcinoma patients as well as in the extract of hehatocellular carcinoma tissue were measured. With the hemolysate, 4 out of 7 hepatocellular carcinoma cases showed slight but definite increase, 2 out of 10 in the serum and 6 out of 8 in the tissue extract. No such excess of fetal hemoglobin was found in cirrhosis or metastatic hepatic cancer cases as far as examined. Immunofluorescent study revealed that the mode of fetal hemoglobin distribution in the red blood cell in cases of hepatocellular carcinoma was quite similar to that in other instances of fetal hemoglobin increase, such as leukemia, aplastic anemia, etc. Immunochemical analysis of fetal hemoglobin appearing in cases of hepatocellular carcinoma again revealed quite the same character as the one existing in the normal cord blood. Discussions are made on the rationality in considering fetal hemoglobin as one of carcinoembryonic proteins on the one hand, on the similarity and difference between fetal hemoglobin and alpha-fetoprotein on the other.View full abstractDownload PDF (1166K) -
MASAHIKO OKUDAIRA, KEN-ICHI SASAKI1979 Volume 26 Issue 3 Pages 215-230
Published: October 15, 1979
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe results obtained by injection studies on normal vascular patterns of the liver and their architectural changes in various hepatic malignancies were described. Multiferous histopathological and microangiographical characteristics of primary focus of hepatocellular carcinoma (HCC) were pointed out. For the accurate determination of grade of malignancy of HCC should be based on the predominant type of differentiation. The reason of a low incidence of distant metastasis of HCC was discussed.View full abstractDownload PDF (25620K) -
HEPATOCELLULAR CARCINOMA AND PORTAL HYPERTENSIONTOSHIRO NAKASHIMA, KAZUYOSHI SAKAMOTO, TAMIO IKARI, SADAAKI KUWAO, EIS ...1979 Volume 26 Issue 3 Pages 231-245
Published: October 15, 1979
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSPatients with hepatocellular carcinoma developing remote extrahepatic metastases and portal hypertension seem to be encountered clinically more often in recent years, presumably due to prolonged survival attributable to early diagnosis and chemotherapy. The cause of portal hypertension was investigated from the pathological point of view in 225 autopsy livers bearing hepatocellular carcinoma. It was found that the contributing factors are : 1) compression of small hepatic vein branches by regenerative nodulues of the accompanying cirrhosis, 2) increased arteries supplying the tumor and marked increase of arterial blood flowing into the liver, 3) abnormal communications between the hepatic artery and portal vein through tumor thrombi, and 4) marked disturbances in venous blood flow in the liver due to tumor thrombi and dilated arterio-portal anastomoses through plexuses of capillaries around the bile ducts.View full abstractDownload PDF (17922K) -
KUNIO OKUDA, YASUHIKO KUBO1979 Volume 26 Issue 3 Pages 247-260
Published: October 15, 1979
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSA classification of the patients with hepatocellular carcinoma based on clinical manifestations and disease course is proposed. It is primarily based on the Berman's classification (1951) with additional three more types, namely, “frank”, “febrile”, “acute abdominal”, “metastatic”, “occult”, “cirrhotic”, “cholestatic”, and “hepatitic” types. Certain clinical characteristics are shown to be related to liver pathology. Such classification is of practical value in assessing prognosis and determining the therapeutic measure. Beside these clinical types, certain features of tumor pathology are shown to be closely related to clinical manifestations, such as encapsulated carcinoma, clear cell carcinoma, sclerosing carcinoma and intravascular tumor growth.View full abstractDownload PDF (18213K) -
ALTERATION OF PARKINSONIAN TREMOR BY L-DOPA AND SURGICAL TREATMENTMASAFUMI YOSHIDA1979 Volume 26 Issue 3 Pages 261-272
Published: October 15, 1979
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSParkinsonian tremor was analysed by accelerometers and electromyogram. Measurement was made during rest, posturing, finger-finger test and finger-nose test of the upper limbs and parkinsonian tremor in different status was characterized by pattern of tremor provocation by above procedures. L-Dopa treatment did not alter parkinsonian tremor markedly, whereas thalamotomy markedly reduced the tremor, especially its resting component. Postoperative residual tremulous movement was dominated by postural and dysmetric components. This residual tremulous movement was correlated to the intrathalamic therapeutic lesions and discussion was made as to the mechanism of tremogenesis.View full abstractDownload PDF (1536K) -
ICHIRO YOSHIDA1979 Volume 26 Issue 3 Pages 273-279
Published: October 15, 1979
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe 4-pentenoic acid, one of short-chain fatty acids, produced fatty changes in rat liver. Abnormal mitochondrial changes had been seen prior to the appearance of fatty droplets by electronmicroscope. Mitochondria were swollen with decreased density of matrix. Dense-bodies were disappeared. Although there had been prominent mitochondrial changes, hepatic ATP concentrations in rats were not decreased. These results suggest that antecedent mitochondrial changes may play a primary role in the pathogenesis of fatty liver induced by 4-pentenoic acid, although hepatic ATP changes in concentration did not accompany the mitochondrial damage.View full abstractDownload PDF (6869K) -
SANAE OKITA, HIROYUKI NAKANO1979 Volume 26 Issue 3 Pages 281-286
Published: October 15, 1979
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe adrenal medulla of the adult cats fixed with various fixative methods were examined by electron microscopy. In addition to the two kinds of well-known typical secretory granules, there existed colloidal bodies usually several times as large as the typical secretory granules in diameter both in the noradrenaline-storing cell and adrenaline-storing cell. They were round or elliptic, sometimes irregular in shape, containing the fine, homogeneous f locculent material with a lower density than that of the typical secretory granules. The mechanism of releasing their contents into the intercellular space was taken into consideration. Moreover, the ability of cell division was also confirmed in the adrenal medullary cells of the adult cat.View full abstractDownload PDF (7345K) -
KOHTA YATSUKA, AKIHIKO IBOSHI, TAKASHI FUKUSHIMA, TAKAAKI KITA, JINRYO ...1979 Volume 26 Issue 3 Pages 287-293
Published: October 15, 1979
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSFrom January 1971 to December 1977 left transdiaphragmatic approach and cervical esophagogastrostomy with gastric tube in one stage without surgical positional change was performed on 53 patients with esophageal cancer of the middle or lower thoracic esophagus. The esophagogastrostomy with end to side anastomosis was constructed in the left neck in 50 patients. There were no instance of postoperative anastomotic leakage or stenosis. Four of these patients died of pulmonary complications or cardiac insufficiency within one month of operation. The operation with this approach has several advantages as follows ; The change of surgical posture was not necessary during the operation. The second merit is a decrease on the incidence of postoperative pulmonary complications depending upon this technic without upper median abdominal incision. Moreover, this approach has another advantage on the dissection of upper mediastinal metastatic lymph nodes such as Botallo's node. 1) 53 cases of the resectable esophageal cancer from 1971 through 1977 in our department, were treated with good prognosis. 2) Mostly, we interposed the plastic gastric tube along the retromediastinal route with few complications. 3) The esophagogastrostomy with end to end or end to side anastomosis individually, according to the general conditions of patients. 4) Early tube feeding by means of a plastic gastric tube showed the ideal physiological quality and provided well improved nutrition. 5) The good adequate blood supply of the plastic gastric tube was found not to cause the ischemic change and the necrosis of its stump. 6) The left transthoracic transdiaphragmatic operative approach diminished the postoperative stress and pulmonary complications. 7) This operation satisfied the radical dissection of lymph nodes. 8) The second operation for closure of fistula is harmless and simple.View full abstractDownload PDF (4200K) -
TSUNETAKA MATOBA, JUN NAKAMURA, KINSHI NAGAE, SHIGEMICHI KAMIMOTO, TAD ...1979 Volume 26 Issue 3 Pages 295-301
Published: October 15, 1979
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSVibration disease results from the usage of vibrating tools such as chain saws or pneumatic hammers for a long period. One of the principal manifestations of this disease is Raynaud's phenomenon in the fingers. In order to examine peripheral circulatory functions, a thermography was applied to the patients with vibration disease. The distribution of skin temperature in digits was clearly demonstrated by a thermography. By combination with auditory stimuli, a thermography showed dynamic changes of skin temperature in time. The recovery time course of skin temperature once reduced by auditory stimuli was related to the activity level of the autonomic nerve. However, this relation was not observed in cold water immersion test which was used as one of the peripheral circulatory function tests. These results suggest that a thermography combined with auditory stimuli is useful to detect not only the distribution of skin temperature but also the activity level of the autonomic nerve.View full abstractDownload PDF (6184K) -
JUNICHI ABE1979 Volume 26 Issue 3 Pages 303-310
Published: October 15, 1979
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe stromal surface of the mammary gland myoepithelial cells of rats under normal and experimental conditions, which were treated with HCl-collagenase method introduced by Evan et al. (1976), have been studied by scanning electron microscopy. Treatment of the mammary gland with HCl and collagenase removed almost completely the extracellular materials such as collagens and the basal lamina and revealed the myoepithelial cells enclosing the glandular alveolus. Myoepithelial cells consisting of an elongated cell body and long, bifurcating processes grasped the glandular alveolus in the form of a delicate network. With the application of oxytocin, the myoepithelial cells were involved in the morphological changes suggestive of contraction. They had a row of prominent folds arranged perpendicularly to the long axis of the cell body and its processes.View full abstractDownload PDF (10046K) -
HIDEKI KIDA, SHIGEMI ANRAKU1979 Volume 26 Issue 3 Pages 311-314
Published: October 15, 1979
Released on J-STAGE: August 11, 2009
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KUNIHIKO FUNATSU, TADASHI NISHIKAWA, NOBUO TOSHIMA, MASATOSHI TANAKA1979 Volume 26 Issue 3 Pages 315-317
Published: October 15, 1979
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSDownload PDF (394K)
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