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Volume 26, Issue 4
Displaying 1-13 of 13 articles from this issue
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SHIGETO YAMADA1979 Volume 26 Issue 4 Pages 319-330
Published: January 31, 1980
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSThe metabolic profiling of rat brain homogenate was performed by gas chromatography-mass spectrometry (GC/MS). Twenty-five compounds in the organic acid fraction in the rat brain homogenate were identified. On the studies of sample preparation, DEAF-Sephadex separation method was more reproducible than solvent extraction. More compounds were detected by the use of ethanol for deproteinization than by the use of perchloric acid (PCA). Changes of the concentration of the compounds during maturation showed good agreements with those of previous report.View full abstractDownload PDF (4431K) -
NAOYUKI USDA, TAKESUKE MUTEKI, MASAHIRO TAJIRI, FUMITAKA TAYAMA, YOSHI ...1979 Volume 26 Issue 4 Pages 331-334
Published: January 31, 1980
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSWe have investigated about the effect of pentoxifylline on the circulatory behavior of the brain by the method of four electrodes impedance plethysmography. Intravenous administration of pentoxifyllines (200 mg) has caused a remarkable increase of the cerebral impedance amplitude which may reflect a pulsatile blood flow increase of the brain with an average increase of 140 per cents of the control. Besides, it has been reported that the clinical case of aortitis syndrome which manifested different cerebral impedance pattern between the right and the left sides with a narrowed lumen or stenosis of the left internal carotid artery. And then this difference in the amplitude of the cerebral impedance has been disappeared with increasing the reduced amplitude in the affected side by administration of pentoxifylline (200 mg I. V.). It may be, therefore, safely asserted that the effect of pentoxifylline upon deformability of the erythrocytes would induce the cerebral blood flow increase remarkably in specific way which is remained to be investigated further.View full abstractDownload PDF (1908K) -
HISAMITSU KOGA, KIYOSHI YANO1979 Volume 26 Issue 4 Pages 335-338
Published: January 31, 1980
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSWe designed “iso-image” in kidney scan with 99 m Tc DTPA and obtained successful results; namely that the administered doses of 99 m Tc DTPA was found to vary according to body weight. We thought that this was useful in the dynamic study in kidney scan.View full abstractDownload PDF (312K) -
(1) MEASUREMENTS OF THE INTERNAL MINOR DIMENSION OF THE LEFT VENTRICLE WITH A PULSE-TRANSIT ULTRASONIC METHODMASUAKI FUJIYAMA, YOICHIRO FURUTA, TOSHIAKI TAKAGI, SHUNPO UEMURA, FUM ...1979 Volume 26 Issue 4 Pages 339-348
Published: January 31, 1980
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSWe measured the internal minor dimension in the normal canine left ventricle using a pulse-transit ultrasonic method. In this report, we explained our methods and techniques, and analyzed the phasic patterns of the dimensional curve. We recognized that our methods and techniques were adequate to measure the internal dimension, and that its phasic patterns were similar to the other reports in the opened chest experiments. The phasic patterns of the dimensional curve were changed under the influencing of the experimental state (opened chest or concious), the site of the transducers in the endocardium and the heart rate. The simultaneous measuring of the pressure and the internal dimension of the left ventricle and the describing of its pressure-dimension loops are the fundamental for the evaluating of the cardiac function.View full abstractDownload PDF (11467K) -
YASUHIRO NAKAMURA, AKIRA TANIMURA, CHIKAI YASUOKA, HIROHISA KATO1979 Volume 26 Issue 4 Pages 349-354
Published: January 31, 1980
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSAn autopsy case of 10 months old male infant with typical type II glycogenosis was reported. In addition to routine histopathological and histochemical studies on skeletal muscle biopsy and specimens obtained at autopsy, histochemical analyses of the enzyme activities, electromicroscopic studies on muscle biopsy, and cardiac muscle and liver obtained at autopsy were employed. In our case, His bundle electrogram was performed and histopathologically the shortening and some degenerations were found in the atrioventricular junction, especially in His bundle and central fibrous body.View full abstractDownload PDF (8314K) -
(1) AGING CHANGES IN THE HUMAN A-V NODE, HIS BUNDLE AND BUNDLE BRANCHAKIRA TANIMURA, NOBUKO NAKAJIMA1979 Volume 26 Issue 4 Pages 355-358
Published: January 31, 1980
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSSeventy-seven autopsy cases were examined about aging process of conduction tissue (A-V node, His bundle and bundle branch). With advancing age, the following changes occured : 1) Fine reticular fibers extended into A-V node and His-bundle from central fibrous body at first decade. After 30 years age collagenous fibers from central fibrous body connected with perivascular fibrosis and then nodal tissue was completely divided an individual nodal fiber. After 50 years age a portion of bundle branch frequently showed focal loss. 2) Nodal fibrosis was related to the myocardial fibrosis, but nodal fibrosis was milder than that of myocardial fibrosis. Close relation between nodal fibrosis and sclerotic change of nodal artery was not found. 3) Fatty infiltration in the conduction tissue was frequently found in all age groups, especially over 4th decade. It was no tendency of increase with advancing age.View full abstractDownload PDF (5154K) -
(2) AGING CHANGES OF SINO-ATRIAL NODESAKIRA TANIMURA, NOBUKO NAKAJIMA1979 Volume 26 Issue 4 Pages 359-362
Published: January 31, 1980
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSEighty two hearts in hypertensives and nonhypertensives were used in order to make the basis of evaluation of the histopathologic finding in sino-atrial node. In early decades, 2/3 or more of sino-atrial node consisted of nodal fiber. With advancing age, collagenous and elastic fibers in nodal tissue increased. Seventh decade or over collagenous and elastic fibers occupied 2/3 or more of nodal tissue. Fatty infiltration into nodal tissue was frequently seen in early life. Changes of central arteries were seen in hypertensives. However, there were no differences between hypertensives and nonhypertensives in sino-atrial nodes.View full abstractDownload PDF (4292K) -
YASUKO KOHNO, KUMIKO MATSUO, SHIGEKO TAKEDA, MASATOSHI TANAKA, NOBUYUK ...1979 Volume 26 Issue 4 Pages 363-369
Published: January 31, 1980
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSQuenching effects of 26 kinds of compounds on the fluorometric assay of tryptophan were studied. Investigated compounds were monoamines, their precursors and metabolites, and drugs used in the study of monoamines. The fluorescence of 1μg of tryptophan was decreased in the presence of the same amount of L-DOPA, catecholamines, DOPAC, 5-HTP, 5-HT, MK 486 or Ro 4-4602 when these samples were prepared in 0.1 M phosphate buffer (pH 7.4) and estimated by the method of Denckla and Dewey. The degree of quenching was varied according to the diluent of the compounds and tryptophan. These results suggest that the direct application of the ultraf iltrate for the assay of free tryptophan might be quenched after administration of drugs. The decreased fluorescence of tryptophan by above compounds, except 5-HTP, was recovered after introducing separation procedure of tryptophan by the Dowex column.View full abstractDownload PDF (951K) -
KIICHIRO MORITA, EIJI KATO, KENJI KUBA1979 Volume 26 Issue 4 Pages 371-376
Published: January 31, 1980
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSEffects of caffeine (2-6 mM) on the nicotinic transmission of the bullfrog sympathetic ganglion was studied by using an intracellular recording technique. Caffeine (2-4 mM) decreased the amplitude, quantal content and quantal size of the fast e. p. s. p. and the amplitude of ACh potential. Under these conditions, resting membrane potential was almost unchanged with a slight decrease in the membrane resistance. Injection of “EGTA” increased the amplitude of the fast e. p. s. p. under the effect of caffeine (6 mM). These results suggest that caffeine suppresses the nicotinic transmission of the bullfrog sympathetic ganglion by both the pre- and postsynaptic actions and that a considerable portion of the postsynaptic action was the result of a rise in the intracellular free Ca2+ concentration.View full abstractDownload PDF (2617K) -
TAKAYUKI TOKIMASA, HIROSHI HASUO, KYOZO KOKETSU, SHOICHI MINOTA1979 Volume 26 Issue 4 Pages 377-379
Published: January 31, 1980
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSDecreases in the amplitude and duration of the action potential of bullfrog atrium muscle by the mu scarinic action of ACh or carbachol, were found to be restored to a certain extent when the application of ACh or carbachol was sustained. This suggests that the muscarinic receptor-ion channel complex which is responsible for these decreases shows the desensitization to the action of ACh or its agonist.View full abstractDownload PDF (1624K) -
MEGUMU YOSHIMURA, HIDEHO HIGASHI, SYOGORO NISHI1979 Volume 26 Issue 4 Pages 381-385
Published: January 31, 1980
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSIntracellular recording was made from B neurons of bullfrog paravertebral ganglia in situ. Analysis of the tonically occurring fast e. p. s, p. s revealed that approximately 50 % of B neurons receive a multineuronal innervation and that the rest receive a unineuronal innervation which had been thought to be the characteristic innervation pattern in the amphibian sympathetic ganglia. Similar results were also obtained from the analysis of the fast e. p. s. p. s evoked by stimulation of the spinal nerves containing the spinal B fiber outflows.View full abstractDownload PDF (2605K) -
MITSUO YOKOYAMA, C. HOWARD TSENG, WILLIAM T. CHAO, MICHAEL J. O'DONNEL ...1979 Volume 26 Issue 4 Pages 387-395
Published: January 31, 1980
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSOur study was undertaken to determine if the humoral immune status of leprosy patients varied with either the type of the disease or the geographic location of the disease. Another variable investigated was whether or not treatment versus non-treatment had any selected effect on the humoral immune status. Serum immunoglobulin levels were determined by single radial immunodif f usion and other immunoserologic profile testing was performed whenever possible. Immunoglobulin levels did show a difference between the different disease types of leprosy and the authors also feel that environmental and genetic factors may play a more significant role than previously thought.View full abstractDownload PDF (984K) -
PRELIMINARY REPORTMASAHIRO NAKAMURA1979 Volume 26 Issue 4 Pages 397-400
Published: January 31, 1980
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSEffect of soluble starch on the growth of Mycobacterim lepraemurium in cell-free liquid medium was studied. The growth of M. lepraemurium was significantly stimulated when soluble starch was added to NC-5 medium at the final concentration of 0.2 %. A lot of clumps of bacterial cell was found in the smear for bacillary count at the cultivation period of 6 to 8 weeks at 30°C.View full abstractDownload PDF (3191K)
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