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Volume 32, Issue 4
Displaying 1-10 of 10 articles from this issue
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An Experimental StudyKAZUNORI FUKUDA, SHIN - ICHI MATSUMOTO, MASAYOSHI KAGE, MASAHIRO ARAKA ...1985 Volume 32 Issue 4 Pages 255-261
Published: March 31, 1986
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSThe pathogenesis of idiopathic portal hypertension (IPH) was explored in animal experiments. In order to produce experimentally a condition of portal hypertension, portal vein embolization by lycopodiums and structural liver damage by intraportal injection of toxic chemicals were produced in rabbits. Obliteration of intrahepatic portal vein branches alone did not produce sustained portal hypertension due to the development of adequate intrahepatic collateral vessels. Liver damage induced by chemicals was morphologically similar to that seen in IPH and was associated with an increase of portal venous pressure for several months; however, portal venous pressure gradually declined and significant splenomegaly could not be produced. Besides hepatic vascular resistance due to obliteration of intrahepatic portal vein branches and structural liver damage, the possibility of the existence of additional factor (s) is suggested to explain portal hypertension and marked splenomegaly in IPH.View full abstractDownload PDF (4494K) -
TSUYOSHI NISHIMURA, YASUAKI FUJIYOSHI, KOJI IRIE, AKIRA TANIMURA1985 Volume 32 Issue 4 Pages 263-271
Published: March 31, 1986
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSInfluenzal pneumonia was experimentally induced in mice. The respiratory system during the acute phase was investigated by light and electron microscopy. Bronchial desquamation and necrosis were noted from the 2nd day to the 5th day and were most noticeable during the 3rd day. An electron dense degenerative substance was demonstrated in the degenerated epithelial cells on the 2nd and 3rd days. On the 3rd day, flattend basal cells appeared in the large bronchus. The basal cells were covered with one layer of cuboidal or flattened epithelial cells, both ciliated and non-ciliated. The epithelial cells had large nuclei and narrowly restricted cytoplasm. On the 5th day, stratified regenerating epithelial cells lined both the large and small bronchi. In the large bronchus, non-ciliated epithelial cells had cytoplasmic projections. Alveolar epithelial desquamation and necrosis, interstitial pneumonia and collapse of the lung were noted from the 2nd to the 5th day. On the 4th day, the collapse of the lung was most noticeable. No regenerative alveolar epithelium was demon-strated in these experiments.View full abstractDownload PDF (10172K) -
TEIJI HAMADA, KIYOTAKA YOSHIMATSU, TOSHIYUKI OOSHIMA, NORIO KUBO, MASA ...1985 Volume 32 Issue 4 Pages 273-278
Published: March 31, 1986
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSThe 75g GTT was performed on 722 pregnant women to clarify the glucose tolerance during pregnancy. The results were as follows : (1) Plasma glucose values after 75g GTT were the same in category A (with potential diabetes or glycosuria) before and after 28 weeks of pregnancy, but for women in categories B (without potential diabetes and glycosuria) and C (excluding the neonatal complications in category B), the plasma glucose values were higher during or after 28 weeks of pregnancy than before the 28th week. (2) The plasma glucose after glucose loading was higher in category A than in category B or C, but there was no difference between category B and C. (3) The plasma insulin values in category B were the same before and after 28 weeks of pregnancy; but for women in categories A and C, the values were significantly higher after 28 weeks of pregnancy. (4) The incidence of a low insulinogenic index was 12.1% in category A, which was significantly higher than the indexes for categories B and C. These results may be useful to establish the normal limit of glucose values after 75g glucose loading during pregnancy.View full abstractDownload PDF (696K) -
TEIJI HAMADA, KIYOTAKA YOSHIMATSU, TOSHIYUKI OOSHIMA, NORIO KUBO, TOSH ...1985 Volume 32 Issue 4 Pages 279-283
Published: March 31, 1986
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSThe 75g GTT was performed on 259 pregnant women to clarify the relationship between age and glucose tolerance during normal pregnancy. Glucose tolerance in healthy women during late pregnancy gradually decreased with advancing age. In pregnant women over 30 years of age, the average plasma glucose levels after glucose loading were significantly higher than the levels at 20-24 years of age. These findings will be useful in the determination of screening criteria for gestational diabetes mellitus.View full abstractDownload PDF (502K) -
TEIJI HAMADA, KIYOTAKA YOSHIMATSU, TOSHIYUKI OOSHIMA, NORIO KUBO, JUNJ ...1985 Volume 32 Issue 4 Pages 285-291
Published: March 31, 1986
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSPlasma glucose and plasma immunoreactive insulin (IRI) levels were measured during the 75g glucose tolerance test (GTT) in healthy pregnant women, to clarify the changes of glucose metabolism during the last trimester of pregnancy. The glucose tolerance decreased with gestational time. After 33 weeks of gestation, the peak levels of the post-glucose loading occur-red at 60 minutes instead of 30 minutes after glucose ingestion. The parameter that best reflected the decrease in glucose tolerance was the level 60 minutes after glucose ingestion, which at the 33rd gestational week was significantly higher than the level at the 28th gestational week. The IRI reaction accompanying the rise in plasma glucose appeared to increase gradually during gestation, even in the last trimester. The largest increases of plasma IRI levels after glucose loading were seen at or after the 36 th week of gestation.View full abstractDownload PDF (702K) -
SEIZABURO KASHIWAGI, JUN HAYASHI, HIDEYUKI NOMURA, WATARU KAJIYAMA, HI ...1985 Volume 32 Issue 4 Pages 293-296
Published: March 31, 1986
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSAn outbreak of Mycoplasma pneumoniae infections was demonstrated to have occurred from August to September 1984 in a hospital in Japan. This was the first recognized outbreak of the disease in a hospial. Eight elderly (50-86 years old) inpatients with underlying disease were affected. Five patients developed pneumonia and 3 bronchitis. Two patients, a 50-year-old male and a 75-year-old female, died. Both deaths were thought to be primarily due to underlying disease, liver cirrhosis in the male and cardiovascular disease in the female.View full abstractDownload PDF (457K) -
TOSHIMITSU SHINGU, KAYOKO YAMAMOTO, SEIZABURO KASHIWAGI, WATARU KAJIYA ...1985 Volume 32 Issue 4 Pages 297-300
Published: March 31, 1986
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSA 16-year-old Japanese boy with hemophilia A had been treated with commercial high-purity factor VIII concentrates since he was eight years old. He was negative for antibodies to human T-lymphotropic virus III (anti-HTLV-III) in Nov. 1982, but he became positive for anti-HTLV-III by Feb. 1983. Although the percentage of T4 helper/inducer cells and T4/T8 ratios were low, he was in good health and never complained of AIDS-like symptoms.View full abstractDownload PDF (439K) -
OSAMU NAGATA, KOJI UTO, HISAYO SUGIHARA, MASARU TAKII, YUMIKO NOHARA, ...1985 Volume 32 Issue 4 Pages 301-305
Published: March 31, 1986
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSImaging diagnosis based on ultrasonic findings of the liver with Schistosomiasis Japonica has been recently reported (Nakayama et al. 1981; Uto et al. 1984). In the present study, attempts were made to classify the ultrasonic patterns of the liver infected with Schistosoma Japonicum. The calcification and fibrosis of the liver were evaluated by comparative investigation with an ultrasonogram and computed tomography (CT). Schistosomiasis Japonica was examined in 23 patients who were more than 45 years of age. It was diagnosed by liver needle biopsy, an intracutaneous test, or autopsy. The cases with a fish scale and network pattern had attenuation of the liver on ultrasonography and were unspecific on CT. Histological findings demonstrated moderate liver fibrosis. The cases with a sieve pattern had attenuation on ultrasonography, and the CT disclosed a retractive liver and the CT number of that liver was increased. Histological findings demonstrated a severe fibrotic liver. The cases with a mottled pattern had increased reflective spotty echo with an acoustic shadow, and the CT disclosed calcification. The histological findings demonstrated a marked calcification of the eggs. The cases with a mixed pattern, which consisted of mottled and sieve based on fish scale and network, had no retraction with less increase in the CT number. These results suggest that the peculiar reflective echo pattern of Schistosomiasis Japonica was due to not only calcification but also fibrosis of the liver.View full abstractDownload PDF (3635K) -
MASARU TOMIMATSU, JUN NAKAMURA, YOICHIRO INOUE, HIDEKI KOJIMA, SHIGEMI ...1985 Volume 32 Issue 4 Pages 307-309
Published: March 31, 1986
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSDownload PDF (2151K) -
MUNEYASU SHIROZU, MASAHIKO HASHIMOTO, MASARU TOMIMATSU, YOICHI NAKAZAW ...1985 Volume 32 Issue 4 Pages 311-313
Published: March 31, 1986
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSDownload PDF (1974K)
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