The Kurume Medical Journal
Online ISSN : 1881-2090
Print ISSN : 0023-5679
ISSN-L : 0023-5679
Volume 34, Issue 4
Displaying 1-7 of 7 articles from this issue
  • Observations from 25 Autopsies
    KAZUNORI FUKUDA, MASAHIRO ARAKAWA, MASAYOSHI KAGE, MASAMICHI KOJIRO
    1987 Volume 34 Issue 4 Pages 165-175
    Published: March 31, 1988
    Released on J-STAGE: February 08, 2010
    JOURNAL FREE ACCESS
    Pathomorphological changes in the liver were studied in 25 Japanese autopsy cases of idiopathic portal hypertension (IPH), and the cause of histological progression of the hepatic lesion was discussed. The morphological changes in the IPH livers differed markedly from case to case, probably because of the different stages and/or different degrees of severity of the lesion. Most of the patient who had died of hepatic failure were elderly or had an advanced stage of the disease. The livers from these patients were usually atrophied. Parenchymal atrophy of the IPH livers is caused by an insufficiency of the portal blood supply, which is accelerated by progression of phlebosclerotic changes, secondary thrombi of the portal vein branches, and a decrease in the intrahepatic collateral vasculature. Although it is possible that aging and a prolonged duration of the clinical course are contributory factors in the progression of portal lesions, the pathogenesis of portal phlebosclerosis cannot be explained by passive congestion, alone. In the IPH liver, parenchymal atrophy and regeneration seem to exist together. It therefore appears that failure of compensatory parenchymal regeneration due to insufficient blood supply is a major factor in liver atrophy and deterioration of liver function.
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  • HIROYOSHI MIZOTE, GU LIN, SHIGEKI HIKIDA, YOSHIAKI TANAKA, RINKEN YOH, ...
    1987 Volume 34 Issue 4 Pages 177-182
    Published: March 31, 1988
    Released on J-STAGE: February 08, 2010
    JOURNAL FREE ACCESS
    Changes in acid-base balance, water-electrolyte metabolism and CVP were evaluated in 315 patients with postoperative ileus during the past 21 years. Infusion therapy for postoperative ileus is described.
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  • JINRYO TAKEDA, KEN HASHIMOTO, JUNJI MACHI, YUH HIRAI, CHIKARA YOSHIDA, ...
    1987 Volume 34 Issue 4 Pages 183-191
    Published: March 31, 1988
    Released on J-STAGE: February 08, 2010
    JOURNAL FREE ACCESS
    Four hundred fifty-nine solitary early gastric cancers were studied, retrospectively. There were 313 men and 146 women. The proportion for solitary early gastric cancer of the total gastric cancers was 23.4% (459/1960). Early cancers were grossly divided into three fundamental types. One hundred nine cancers (23.7%) were the elevated type, 8 cancers (1.7%) were the flat type, and the depressed type was the most frequent, present in 342 of the patients (74.5%). Early cancers were also divided into two groups based on the depth of cancer invasion. Cancers confined to the mucosa, m-cancers, were observed in 220 patients (47.9%), whereas cancers invading the submucosa, sm-cancers, were seen in 239 patients (52.1%). On microscopic examination, 329 cancers (71.7%) were the differentiated type and the remaining 130 cancers (28.3%) were the undifferentiated type. Positive lymph node metastases were noted in 48 of 459 patients, which is a lymph node metastasis rate of 10.4% . With m-cancers, only 4.1% (9/220) had lymph node metastases. On the other hand, in sm-cancers, 16.3% (39/139) had lymph node metastases (P<0.001) . The 5-year and 10-year survival rates were 96.8% and 96.8 % in m-cancer, and 94.8% and 90.1% in sm-cancers. The survival rates for differentiated land undifferentiated types of cancers were not significantly different.
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  • NOBUO KAKU, TAKAHIRO AKASHI, MASAHIRO SHINOZAKI, TAKESUKE MUTEKI
    1987 Volume 34 Issue 4 Pages 193-201
    Published: March 31, 1988
    Released on J-STAGE: February 08, 2010
    JOURNAL FREE ACCESS
    The prognosis for fulminant hepatitis (FH) complicated by in-fections is poor with a progressive reduction of host immuno-competency. Im-munological differences were examined in 13 patients who survived FH and 19 patients who died from the disease. Although T cells were at normal levels in those who survived the disease, they were reduced in many of those who died. B cells were markedly reduced both in the survivors and non-survivors. Lym-phocyte function, as evaluated by Con-A stimulation, tended to be greater in the survivors. Lymphocyte subset studies using monoclonal antibodies revealed normal or slightly reduced OKT 11, slightly increased OKT 4, and slightly re-duced OKT 8 and OKIa 1. For B cell subsets, IgG was markedly reduced from normal levels, IgA was slightly reduced, but the IgM level was normal. Im-munoglobulin (IgG, IgA, and IgM) levels were normal in both groups of pa-tients, but were significantly higher in the survivors than in the non-survivors. Transferrin was reduced in both groups; and it decreased significantly (p<0.05) during the hospitalization of the non-survivors. Fibronectin was reduced in both groups on admission, but it increased significantly (p<0.01) in the survivors while it decreased significantly (p<0.05) in those who died during hospitalization.
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  • A case report
    TOSHI ABE, HIDEAKI FUJITA, SHUUICHI HIGANO, NORIAKI TOMURA, ATUSHI INU ...
    1987 Volume 34 Issue 4 Pages 203-206
    Published: March 31, 1988
    Released on J-STAGE: February 08, 2010
    JOURNAL FREE ACCESS
    A case involving a 37-year-old man who suffered from a subarachnoid haemorrage due to a ruptured aneurysm arising from a fenestration of the basilar artery was reported. Previous reports were also reviewed. Hemodynamic mechanisms and local histological fragility were considered to be causative factors. Stereoscopic magnification angiography with an oblique projection was a useful technique for the diagnosis of the aneurysms.
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  • TAKAYUKI TOKIMASA
    1987 Volume 34 Issue 4 Pages 207-211
    Published: March 31, 1988
    Released on J-STAGE: February 08, 2010
    JOURNAL FREE ACCESS
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  • MASASHI TSURUSAKI
    1987 Volume 34 Issue 4 Pages 213-216
    Published: March 31, 1988
    Released on J-STAGE: February 08, 2010
    JOURNAL FREE ACCESS
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