All issues
Volume 37, Issue 3
Displaying 1-12 of 12 articles from this issue
- |<
- <
- 1
- >
- >|
-
AKIRA SHIDATA, KATSUHIRO FUKUDA, TOMIO HIROHATA1990 Volume 37 Issue 3 Pages 129-140
Published: November 01, 1990
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe present study was conducted to provide baseline data for an anti-smoking educational program. Nineteen public senior high schools in a prefecture in Kyushu, Japan, participated in the study. In July 1982, unsigned self-administered questionnaires on smoking habits were answered by 4689 students—3088 males and 1601 females—during a homeroom under the supervision of their class teacher. The proportions of students who admitted that they had smoked cigarettes were 45.9% for males and 18.2% for females at the ordinary schools, and 78.1% for males at vocational schools. Eleven to twenty percent of male students had already smoked cigarettes in primary school. More male students in vocational schools had smoked than either male or female students in ordinary schools. Over 40% of vocational school students were regular smokers, in contrast to 11.8% for males and 3.4% for females at ordinary schools. It was also noted that the younger the students, the earlier the age at which they had smoked their first cigarette. The incidence of smoking at the primary school age appeared to be correlated with the incidence of smoking by a family member and at high school age with the incidence of smoking by a friend. Spending money and a friend who smoked were strongly associated with current smoking status of high school students, while parental smoking had a weak association. These results suggest the need for antismoking education beginning in a lower grade in primary school.View full abstractDownload PDF (3563K) -
MASAHARU KONDO, CHIZUKO TANOUE, SHIGERU YAMAMOTO, MASAHISA SHINGU1990 Volume 37 Issue 3 Pages 141-147
Published: November 01, 1990
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe culture filtrate of G. haemolysans enhanced the growth of mycobacteria. The enhancing substance seemed to be effectively produced in BHI broth supplemented with human blood. The mycobacterial growth was inhibited by high concentrations of the culture filtrate, but was markedly enhanced at low concentrations such as 1/32 or 1/64 dilutions. The generation time at log phase was 7 to 9 hours compared with 14 hours for the control, leading to rapid detection of mycobacteria in culture. With sputa specimens from tuberculosis patients, the culture time to visual detection of mycobacterial growth was decreased by 59 to 67%.View full abstractDownload PDF (5459K) -
MASANOBU CHINAMI, KENTARO YUGE, MASASHI GOTO, YASUSHI OHTSU, MASAHISA ...1990 Volume 37 Issue 3 Pages 149-152
Published: November 01, 1990
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSTo study the effect of phosphorylation on protein conformation, a fluorescence spectroscopic study was performed on phosphorylated enolase and histoneHl proteins. The peak of fluorescence was 330 and 360 nm for each protein, respectively, when excited at 287 nm. The intensities of the fluorescence were measured during the phosphorylation reactions with the protein kinase A and p43v-abl, for serine, threonine and tyrosine, respectively. Slightly increased intensities at 330 and 360 nm for enolase and histoneH1 protein were observed by phosphorylation with p43v-abl, whereas decreased intensities occurred with the protein kinase A catalytic subunit. These data suggest that micro-structural changes are induced at the residue, either tyrosine, serine or threonine in the protein.View full abstractDownload PDF (396K) -
MASANOBU CHINAMI, MASAHISA SHINGU1990 Volume 37 Issue 3 Pages 153-157
Published: November 01, 1990
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe ATPase activity of RecA protein was examined by monitoring the changes of NMR phosphorus signals of ATP, ADP and inorganic phosphate. The areas of phosphorus-31 NMR peaks from inorganic phosphate and ADP, which increased with time, and the signals from ATP, which decreased with time, were fitted by a linear least square method to obtain the initial rate constants. The rate constants were examined for dependence on RecA protein concentration, temperature and pH. This assay system is useful for testing extrinsic physico-chemical effects on ATPase activity; because only essential components are present in a confined system, and the rate constants can be measured with a single step.View full abstractDownload PDF (1474K) -
KEN HASHIMOTO, JINRYO TAKEDA, TAKAHO TANAKA, KIKUO KOUFUJI, TOSHIO IWA ...1990 Volume 37 Issue 3 Pages 159-164
Published: November 01, 1990
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe results of the surgical resection of the paraaortic lymph nodes metastases of the gastric cancer were evaluated in 116 cases. The frequency of the dissection of paraaortic lymph nodes (No. 16 lymph node) was 20%; the metastatic ratio was 24%. When classified by regions, the highest frequency of metastasis was observed in the cases of upper gastric cancer. The effect of the dissection of No. 16 was more conspicuous when No. 16 metastases were absent than when No. 16 metastases were present. Particularly, the prognosis was improved in the case of n1 and n2 population of the cases which were positive with respect to the proximal lymph node metastasis. It appears altogether that the dissection has considerable significance as prophylactic treatment.View full abstractDownload PDF (2802K) -
JINRYO TAKEDA, KEN HASHIMOTO, TAKAHO TANAKA, KIKUO KOUFUJI, TOURU UMEZ ...1990 Volume 37 Issue 3 Pages 165-170
Published: November 01, 1990
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSFrom 1985 to 1989, a total of 598 gastric cancer patients underwent gastrectomies in the First Department of Surgery at Kurume University School of Medicine. Of these, 24 patients (4.0%) incurred a subphrenic abscess, postoperatively. Subphrenic abscesses occurred most frequently after total gastrectomies at a rate of 17 of 197 (8.8%) cases. Leaking gastrointestinal anastomoses were responsible for 12 of the 17 (70.5%) abscesses. In 384 cases of distal gastrectomy, only 6 (1.69) cases with a subphrenic abscess occurred, and only 3 were due to anastomotic leakage. Among the total of 24 cases with subphrenic abscesses, 16 (67%) were related to an anastomotic leakage including a pancreatic fistula, while the other 8 (33%) showed no leakage by contrast roentgenography. When chest roentgenography shows a pleural effusion and an elevation of the diaphragm, then a subphrenic abscess must be suspected. The majority of patients were treated by replacing the intraabdominal drainage catheter inserted during the gastrectomy with a larger catheter. The overall operative mortality rate was 4.1%, due to a death in only one (MOF) patient.View full abstractDownload PDF (1922K) -
A Case ReportMASAYUKI NAKAMURA, AKIHIRO IEMURA, MASAMICHI KOJIRO, HIROSHI UMETANI, ...1990 Volume 37 Issue 3 Pages 171-175
Published: November 01, 1990
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSA 57 year-old man was admitted to the hospital because of bloody stools. A barium enema and coloscopy disclosed a tumor of the rectum. The resected tumor was diagnosed as a leiomyosarcoma, histologically. Many epithelioid granulomas with Langhans type giant cells were found in the tumor, and there was no evidence suggestive of generalized sarcoidosis, tuberculosis or mycosis. Thus, the epithelioid granulomas seen in the leiomyosarcoma were interpreted as a sarcoid-like reaction. As far as could be determined, there has been no reported case of a sarcoid-like reaction associated with a leiomyosarcoma. The occurrence of the sarcoid-like reaction in the present case could be due to the reaction to the metabolites or a degenerative substance of the leiomyosarcoma, or to host resistance to the tumor itself.View full abstractDownload PDF (4886K) -
TADASHI ISOMURA, KOUICHI HISATOMI, HIROTO INUZUKA, SHIGEMITSU SUZUKI, ...1990 Volume 37 Issue 3 Pages 177-183
Published: November 01, 1990
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSWe examined the ultrastructure of right and left ventricular myocardial biopsies obtaind prior to cardiopulmonary bypass in fourteen patients undergoing total correction of tetralogy of Fallot (TOF). Twelve patients were undergoing primary one-stage repair and two patients had had a previous Blalock-Taussig shunt operation. The ages of the patients ranged from 3 to 35 years. In left ventricular (LV) myocytes, the sarcolemma often formed pouches filled with mitochondria and the muscle fibers showed a disoriented arrangement. In addition, the myofibrils showed hypercontraction and the Z-bands were thickened; the degree of the myofibril contraction was more severe than that in right ventricular (RV) myocytes. These ultrastractural findings are similar to those observed in myocytes under hypoxic conditions. The number of lysosomes in LV myocytes, but not in RV myocyte increased in the older patients. While we have not established a causal relationship between the ultrastractural findings and clinical features in our cases, our observations are consistent with the possibilitv that early total correction of TOF may be required to prevent the development of hypoxic changes and degeneration of heart muscle.View full abstractDownload PDF (4900K) -
TADASHI NISHIKAWA, ITSUYUKI KOGA, YASUNORI UCHIDA, MASATOSHI TANAKA1990 Volume 37 Issue 3 Pages 185-187
Published: November 01, 1990
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSTwo cases of tardive akathisia, which were misdiagnosed as anxiety originating from a schizophrenic disorder, had been treated with anxiolytics in addition to neuroleptics and anticholinergics. The diagnoses wère changed to tardive akathisia, the anticholinergics were discontinued, and the patients were treated with clonidine successfully. In view of the similar effects of clonidine and anticholinergics, the pathophysiology of tardive akathisia must be very similar to that of tardive dyskinesia.View full abstractDownload PDF (350K) -
SHINSHI NODA, SHIGERU MIYAHARA, KEI MATSUOKA, KOSAKU ETO, YUHEI ITO, S ...1990 Volume 37 Issue 3 Pages 189-193
Published: November 01, 1990
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe outcome of antireflux surgery for vesico-ureteral reflux (VUR) was studied in 39 children (65 renal units). The T max of the renogram improved significantly after operations in 51 (78.5%) of the 65 renal units due to a reduction of the back pressure. Improvements in scarring were observed in only 3 (7.3%) of 41 scarred kidneys. The growth of 38 kidneys was examined using the renal ratio, more than 2 years (mean, 3 years and 1 month) after the operation. The normal renal ratio was restored in 1 of 12 small kid-neys with a preoperative size of less than the mean -2SD. The other 11 kidneys remained small, but 6 of these grew with a normal growth curve. The growth of the remaining 5 kidneys was unremarkable. Of the 26 kidneys with a normal renal ratio, 4 became small after the operation, but all the others had growth within the normal range.View full abstractDownload PDF (2180K) -
A report of studies in SwedenAKIO KATAOKA, MICHIAKI YAKUSHIJI1990 Volume 37 Issue 3 Pages 195-201
Published: November 01, 1990
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSHuman papillomavirus (HPV) was detected by non-isotopic sub-genomic probes on Southern blot hybridization (Oncor Inc. Gaithenberg, MD). The 108 samples which were obtained from patients below the age of 30 (mean age 19.0±2.8 yrs). All samples were collected from the ectocervical mucosa by CytobrushR (Medscand, Malmö, Sweden) as previously described. HPV-DNA was detected in 16 cases (15%). In 36 cases (33%) the patients presented clinical findings of condyloma or cervical intra-epithelial neoplasia (CIN) at simultaneous vaginal ectocervical smears. HPV-DNA was detected in 12 out of 36 cases. On the other hand, in the patients without subclinical findings HPV-DNA were detected in only 4 out of 70 cases (6%). HPV-DNA was detected in one of the 4 patients with accuminate condyloma of the cervix and in 4 out of 16 cases with similar lesions in the vulva. The only HPV type found in these patients was type 6. Papillomavirus was also detected in 5 out of 16 cases (31%) with flat condylomas, most studied types being represented here. CIN was only reported two patients both of them carrying HPV-DNA (types 16 and 18 respectively). The most common type of virus was HPV 6. Combined infections with two or three types were seen in 5 out of 16 HPV-positive cases (31%). Such cases are readily detected and typed with the present Southern blot procedure, where the use of subgenomic probes enables the distinction of all types, even when present in the same sample.View full abstractDownload PDF (861K) -
Clinical Evaluation and Arachidonic acid MetabolismTEIJI AKAGI, HIROHISA KATO, OSAMU INOUE, NOBORU SATO1990 Volume 37 Issue 3 Pages 203-208
Published: November 01, 1990
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSAspirin is the basic treatment for Kawasaki disease, however its optimal dose is, controversial. We investigated the therapeutic efficacy of highdose (100 mg/kg/day, n=30) versus low-dose (30 mg/kg/day, n=30) aspirin. Duration of fever, trasaminase, plasma thromboxane B2 (TxB2) and 6-ketoprostaglandin F1α (PGF1α) levels were compared before enrollment and on days 4, 7 and 14. In the high-dose group, duration of fever was significantly shorter than that of low-dose group (3.2±1.8 versus 5.4±4.3 days, p<0.05), however, serum glutamic pyruvic transaminase levels were elevated (157.4±187.7 versus 48.0±58.2I.U./liter, p<0.005). No differences in the incidence of coronary artery lesions were observed (5 of 30 versus 7 of 30). Plasma TxB2 production was completely blocked in both groups, plasma 6-keto-PGF1α levels in the high-dose group on day 14 was lower than that in the low-dose group (39±26 versus 160±207 pg/ml, p<0.05). This latter observation suggest that high-dose therapy may be disadvantageous as anti-thrombotic treatment, and supports the notion that low dose therapy is safe in the acute stage of Kawasaki disease.View full abstractDownload PDF (746K)
- |<
- <
- 1
- >
- >|