All issues
Volume 48, Issue 3
Displaying 1-13 of 13 articles from this issue
- |<
- <
- 1
- >
- >|
-
NAOFUMI ERIGUCHI, SHIGEAKI AOYAGI, TSUYOSHI TAMAE, NAOMITSU KANAZAWA, ...2001 Volume 48 Issue 3 Pages 193-195
Published: September 14, 2001
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThis retrospective study presents the results of surgical treatments for large cyst of the liver over 10 cm in diameter in 9 patients diagnosed and treated at Kurume University Hospital. There were 8 women and 1 man, with an average age of 71.6 years. Although the chief complaints were abdominal pain or fullness, 1 had obstructive jaundice due to biliary compression by a large cyst. Cyst size ranged from 10 cm to 27 cm. There are several treatment modalities for giant hepatic cyst, such as cyst resection, unroofing, and scierotherapy after cyst drainage. Operative procedures in the patients reported here were surgical resection of the liver cyst in 3 patients, unroofing with ethanol scierotherapy in 1 patient and laparoscopic treatment in 2 patients. Sclerotherapy after percutaneous transhepatic cyst drainage was performed in 3 patients because their general condition was poor. There were no postoperative complications among these patients. Costs varied among the patients and depended mainly on the method of treatment and period of hospital stay. We discuss operative procedures and costs of treatment of each patient and review the literature.View full abstractDownload PDF (453K) -
KEISHIRO AOYAGI, KIKUO KOHFUJI, SHOJIRO YANO, NAOTAKA MURAKAMI, MOTOSH ...2001 Volume 48 Issue 3 Pages 197-200
Published: September 14, 2001
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe expression of epidermal growth factor (EGF), epidermal growth factor receptor (EGFR), transforming growth factor α (TGF α), and of c-erbB-2 was immunohistochemically investigated in resected gastric carcinoma (in 39 cases of superspreading type and in 11 cases of penetrating type), to understand the differential biological features of these two types of gastric carcinoma. EGF, EGFR and c-erbB-2 positive cases were preferentially found in penetrating type rather than in superspreading type (p<0.05, p<0.01, and p<0.05, respectively). The positive rates of EGFR and c-erbB-2 were significantly higher in submucosal gastric carcinoma than in intramucosal gastric carcinoma (p<0.01, p<0.05, respectively). These results suggested that the autocrine mechanism of the growth factors and the expression of c-erbB-2 were correlated to the degree of gastric wall invasion.View full abstractDownload PDF (682K) -
YASUMI ARAKI, NOBUYA ISHIBASHI, YUKIYA KISHIMOTO, KEIKO MATONO, MOTONO ...2001 Volume 48 Issue 3 Pages 201-204
Published: September 14, 2001
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe aim of this study was designed to investigate the outcome from using the new circular stapling device in the surgical treatment for mucosal prolapse of the rectum associated with outlet obstruction. The treatment consisted of resection of the mucosal prolapse through a transverse incision and resecting a suitable part of the mucosa between the rectum and the anal canal, using an HCS33 circular stapler. Eleven patients successfully underwent this operation without morbidity or mortality, and were assessed clinically and by rectoanal manometry and defecography pre- and post-operation. The mean operating time was 39 (range 22-49) min. The postoperative proctalgia and complications were mild, and the patients were discharged at 4 days after the operation. The pre-operative constipation was improved, and the patient's satisfaction was increased at one month after operation in comparison with the preoperative level. Rectoanal function test at 6 months after the operation demonstrated normalization of the maximum resting and squeezing pressures of the anal canal and rectal compliance to the normal levels. No patient has had recurrence of symptoms during the follow-up period. Our data suggest that this procedure may be a useful surgical treatment, as it causes little postoperative complication and enables early discharge of the patients. However, long-term outcomes of recurrence, continence, and constipation need to be evaluated in a more extended follow-up.View full abstractDownload PDF (4705K) -
MITSUE TAKEYA, HIROSHI HASUO, NORIHIRO MURAOKA, TAKASHI AKASU2001 Volume 48 Issue 3 Pages 205-210
Published: September 14, 2001
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSChanges in the membrane potential of neurons in the hippocampal CA2 and CA1 regions were recorded by optical recording techniques. After stimulation of the Schaffer collaterals at the hippocampal CA2 region, excitatory optical signals first occurred adjacent stimulus electrode and then flamed-up signals spread toward the hippocampal CA1 region. The optical signal was blocked by tetrodotoxin (TTX) (1 μM). Propagation of the optical signal was blocked in an artificial cerebrospinal fluid (ACSF) containing 0 mM Ca2+ and 6 mM Mg2+. 6, 7-Dinitroquinoxaline-2, 3 (1 H, 4H)-dione (DNQX) (20 μM) also blocked the optical signals that spread to the hippocampal CA1 region. The time course of the optical signal recorded at a unit area (49 pixels) on the propagation pathway was characterized by fast and slow components. TTX (1 μM) blocked both fast and slow components of the optical signal. The slow component of the optical signal was preferentially depressed by either removal of external Ca2+ or by bath-application of DNQX (20 μM). When bicuculline (15 μM) was applied to the bath-solution, the intensity and propagation area of the optical signal were increased. The results indicate that stimulation of the Schaffer collaterals in the hippocampal CA2 region produces the propagation of the optical signal to the hippocampal CA1 region, and that the optical signal involves the action potential and excitatory and inhibitory postsynaptic potentials.View full abstractDownload PDF (7833K) -
YUTAKA OGATA, KAZUHIDE MIURA, AKIRA OHKITA, HIDEAKI NAGASE, KAZUO SHIR ...2001 Volume 48 Issue 3 Pages 211-218
Published: September 14, 2001
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSWe have evaluated the degree of MMP-9 and TIMP-1 messenger RNA (mRNA) expressions according to cell types in tumor tissues, and evaluated the implication of balance between the MMP-9 mRNA and the TIMP-1 mRNA expression in liver metastasis using orthotopicimplanted colon cancer in nude mouse, and also in 47 patients with colorectal cancer. The grade of MMP-9 or TIMP-1 mRNA expression was classified into 4 categories according to positive cell ratio. A higher grade of MMP-9 mRNA expression in tumor cells was correlated with liver metastasis in the experimental colon cancer, but was not statistically correlated in the clinical colorectal cancer. In contrast, the expression of TIMP-1 mRNA in the stromal cells of human colorectal cancer was correlated with liver metastasis. In both experimental and clinical colorectal cancer, a balance between the expression of MMP-9 mRNA and that of TIMP-1 mRNA was correlated with the occurrence of liver metastasis. The imbalance of MMP-9 dominance in tumor cells was implicated in liver metastasis. However, there was no significant relationship between the incidence of liver metastasis and the expression patterns of MMP-9 and TIMP-1 mRNA in the stromal cells. These results suggest that the balance between the expressions of MMP-9 and TIMP-1 in the tumor cells is more closely related to tumor biological behavior rather than the balance in the stromal cells.View full abstractDownload PDF (4416K) -
NAOFUMI ERIGUCHI, SHIGEAKI AOYAGI, TSUYOSHI TAMAE, NAOMITSU KANAZAWA, ...2001 Volume 48 Issue 3 Pages 219-221
Published: September 14, 2001
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSSeven cases of xanthogranulomatous cholecystitis are presented, and their clinicopathological appearance is described. Three men and 4 women with xanthogranulomatous cholecystitis, aged 53-72 years old, were reviewed. Five patients had had previous attacks of acute cholecystitis lasting from 3 weeks to 6 months. Abdominal ultrasonography was performed in all patients, and computed tomography in 5 patients. Cholelithiasis and sludge were present in all patients. The gallbladder wall was thickened in all patients. On computed tomography, one patient showed no abnormal finding, and 4 patients had abnormal findings such as increased wall thickness and irregularity, and pericholecystic abnormalities. A diagnosis of gallbladder carcinoma was made preoperatively in 1 patient. During laparotomy, the gallbladders in all patients showed signs of chronic cholecystitis, and cholecystectomies were performed. Histological findings showed xanthogranulomatous cholecystitis, and 4 patients had stones in the gallbladder wall. Despite the characteristic histologic appearance of xanthogranulomatous cholecystitis, radiologic findings are nonspecific, varying from signs observed in other forms of cholecystitis to the appearance of a gallbladder neoplasm. We report here 7 cases of xanthogranulomatous cholecystitis and review the literature.View full abstractDownload PDF (520K) -
AKIRA ISHIBASHI, YOSHITAKE YOKOKURA2001 Volume 48 Issue 3 Pages 223-226
Published: September 14, 2001
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSAn analysis was conducted to determine at discharge the outcomes associated with risk factors in 246 patients with ischemic cerebrovascular disease who were admitted within 48 hours after the onset of the disease. Statistical analysis in this study disclosed that atrial fibrillation was a significant risk factor contributing to the worse outcomes among the subtypes of the ischemic cerebrovascular disease.View full abstractDownload PDF (1757K) -
TSUNETOSHI ARAKI, NOBUO KAKU2001 Volume 48 Issue 3 Pages 227-231
Published: September 14, 2001
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSTo assess the effectiveness of non-surgical treatment for severe blunt liver injuries, we retrospectively examined the files of 147 patients (excluding cases with cardiopulmonary arrest on arrival). The patients were divided into three groups according to the date of admission: Group-A (1982-85), B (1986-90) and C (1991-95). The patients were further divided on the basis of the type of injury, according to the classification proposed by the Japanese Association for the Surgery of Trauma (JAST). The types of injuries reported here were of type II, IIIa or IIIb. There was no difference in the patients' background, injury severity score (ISS), amount of intra-peritoneal hemorrhage, and amount of blood transfusion among the three groups, A, B and C. Surgical treatment was carried out in all Group-A patients, in 81.8% of Group-B patients and in 31 % of Group-C patients. The hospitalization period was shorter in the Group-C, and the frequency of fatal outcome was also lower in Group-C. Non-surgical treatment has been performed since 1988 in our center, and its frequency has been increasing since then. It was applied to 6 cases (18.2%) of Type II injuries in Group-B. In total, 69% of the cases in Group-C were non-surgically treated, including cases of Type IIIa and Type IIIb injuries. Non-surgical treatment prevented 8 out of 9 cases of severe liver injury from having fatal outcomes in 1995. Moreover, 5 of those cases were of the most serious type (Type IIIb). There were three fatalities in Group-C and none in Group-B. Out of all the non-surgically treated cases, injuries to the head were the cause of fatality. Any treatment of cases showing inferior vena cava damage was generally ineffective due to heavy bleeding, unless the bleeding was stopped by surgical intervention. Non-surgical treatment is suitable for blunt liver injuries, including severe liver injuries, provided that bleeding control and close observation are maintained.View full abstractDownload PDF (2274K) -
FUMIHIKO YAMASHITA, EIZABURO SASATOMI, MASAHARU KIYAMA, KAZUTA FUKUMOR ...2001 Volume 48 Issue 3 Pages 233-236
Published: September 14, 2001
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSA case of gastrointestinal stromal tumor (GIST) in stomach was presented. Serial barium meal x-ray examinations revealed an enlarging elevated lesion on the fornix of the stomach. Tumor volume doubling time was found to be 299 days. Microscopic and immunohistochemical studies of the resected tumor disclosed GIST, uncommitted type, low grade malignant/potentially malignant. A radiographic feature of this rare type of gastric submucosal tumor was demonstrated in this report.View full abstractDownload PDF (6111K) -
A Case ReportTOSHIHIRO NOAKE, SHOGO YOSHIDA, HIROMASA FUJITA, NOBUYA ISHIBASHI, KAZ ...2001 Volume 48 Issue 3 Pages 237-240
Published: September 14, 2001
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSWe report a case of intussusception during enteral nutrition after esophagectomy. The case was a 60-year-old patient who underwent subtotal esophagectomy via the right thoracoabdominal approach, reconstructed with esophagogastrostomy. He underwent tube feeding through gastrostomy after surgery. The tip of the feeding tube was emplaced in the jejunum. He complained of intermittent abdominal pain and the drainage volume through the gastric decompression tube was increased on the 2nd week from surgery. There was no abnormal finding on abdominal CT or on radiography of the digestive tract, and so a diagnosis of intussusception was made and laparotomy was performed. There was descending intussusception with the jejunum where the feeding tube was emplaced. Enterectomy was not necessary in this case. Adult intussusception is rare. The surgery is sometimes the cause for intussusception. Another cause is use of a long intestinal tube. Since enteral nutrition has priority for nutritional support after esophagectomy, it is important to make an early decision whether surgical intervention is required or not, using abdominal examination by CT, ultrasound and contrast radiography, when bowel obstruction occurs during enteral nutrition through a feeding tube.View full abstractDownload PDF (3024K) -
HISAFUMI KINOSHITA, SHINJI SATO, MITSUO HASHIMOTO, KOTARO HASHINO, MAS ...2001 Volume 48 Issue 3 Pages 241-245
Published: September 14, 2001
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSWe report a case of primary hepatocellular carcinoma (referred to as hepatocellular carcinoma below) apparently rupturing after angiography. The patient was a 62-year-old male who was admitted for the treatment of hepatocellular carcinoma. Ultrasonography (US) and computed tomography (CT) on admission showed a tumor occupying the entire left lobe of the liver and partly protruding outside the liver and a tumor embolus in the portal vein. We performed preoperative angiography, after which fever and abdominal discomfort appeared. Two days after the angiography, abdominal pain and a rapid increase in the size of the abdominal tumor were noted. US also revealed an unquestionable increase in the size of the tumor, leading to a diagnosis of intratumoral hemorrhage due to the rupture of hepatocellular carcinoma. Since child classification A, clinical stage I and ICG 11.7% indicated an adequate functional reserve of the liver, we performed an emergency operation. Laparotomy revealed that the tumor occupied almost the entire left lobe of the liver, partly protruded outside it, and was bleeding from part of its anterior surface. The volume of intra-abdominal hemorrhage was about 100 ml. A portal tumor embolus was present in the portal vein from the horizontal part to the trunk. We performed resection of the left and caudate lobes of the liver with removal of the portal tumor embolus. The resected specimens showed a hemorrhage in and around the tumor. We speculated that in a hepatocellular carcinoma that involves the surface of the liver and is complicated by tumor embolism of the portal vein, angiography could trigger the rupture of the carcinoma.View full abstractDownload PDF (10528K) -
TOSHIMASA MATSUOKA, HIROSHI HASUO, TAKASHI AKASU2001 Volume 48 Issue 3 Pages 247-250
Published: September 14, 2001
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSDownload PDF (573K) -
YASUMI ARAKI, NOBUYA ISHIBASHI, YUKIYA KISHIMOTO, MOTONORI NAKAGAWA, K ...2001 Volume 48 Issue 3 Pages 251-253
Published: September 14, 2001
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSDownload PDF (2509K)
- |<
- <
- 1
- >
- >|