The Kurume Medical Journal
Online ISSN : 1881-2090
Print ISSN : 0023-5679
ISSN-L : 0023-5679
Volume 53, Issue 1+2
Displaying 1-7 of 7 articles from this issue
Original Contribution
  • AKIHIKO MIYAMOTO, YUTA SHIBAMOTO, CHIKAO SUGIE, MASATO ITO, SHIHO AYAK ...
    2006 Volume 53 Issue 1+2 Pages 1-5
    Published: July 15, 2006
    Released on J-STAGE: October 11, 2006
    JOURNAL FREE ACCESS
    The purpose of this study was to investigate radioadaptive response in 4 cell-lines under identical conditions using a colony assay. First, 4 cell-lines (V79, HeLa S3, EMT6 and SCCVII) were exposed to 8 Gy at various intervals after pretreatment with an adapting dose of 50 mGy or without it. Second, V79 cells were exposed to 8 Gy at 4.5 hrs after an adapting dose of 0 to 400 mGy. Third, V79 cells were exposed to 2, 4 or 6 Gy at 6 hrs after an adapting dose of 0 or 50 mGy. In the last experiment, an adapting dose was given either immediately after cell plating or 24 hrs later. Cell survival was assessed by a standard colony assay. Adaptive response was not observed in any of the 4 lines tested. In V79 cells, no adaptive response was seen even by changing the adapting dose, challenging dose, and timing of adapting radiation after cell plating. Although radioadaptive response has been reported for the V79 cell-line, we could not reproduce the result. We also failed to demonstrate the phenomenon in the other 3 tumor cell-lines in culture.
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  • JIN SOO PARK, KENSEI NAGATA
    2006 Volume 53 Issue 1+2 Pages 7-12
    Published: July 15, 2006
    Released on J-STAGE: October 11, 2006
    JOURNAL FREE ACCESS
    We describe a technique of double-door laminoplasty for the management of cervical myelopathy using the autologous spinous process instead of an artificial spacer. The aims in the present study were to determine the fusion rate and the incidence rate of breakage in the autologous spinous process, and to assess its efficacy for cervical laminoplasty. Twenty-three patients of cervical myelopathy were treated with double-door laminoplasty followed by implantation of the autologous spinous process. The spinous process from C3 to C7 was resected, at 8 mm from the basal part of the spinous process. The autologous spinous process was made from the removed spinous process, and was implanted between each expanded laminae. Post-operative CT scanning determined the fusion rate between the expanded laminae and the autologous spinous process as 70.4% at 3 months, and 93.5% at 6 months, after the operation. There was no dissociation and no breakage in the autologous spinous process during the follow-up observation period. There were certain advantages to our technique including the high fusion rate and good stability in the autologous spinous process. In addition, this technique was less expensive than other techniques using an artificial spacer. These findings indicated that this technique was a reliable procedure for effectively treating of cervical myelopathy which are caused by multisegmental cervical canal stenosis.
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  • YOSHIKADO MIYAGAWA, YASUNORI MISHIMA, HIDEKI HARADA, SEIJI WATANABE, T ...
    2006 Volume 53 Issue 1+2 Pages 13-22
    Published: July 15, 2006
    Released on J-STAGE: October 11, 2006
    JOURNAL FREE ACCESS
    The present study reports the effects of systemic deep hypothermia (SDH) and subarachnoid block (SAB) on the longitudinally conducting evoked spinal cord potential (conducting ESCP) in man. Before induction of anesthesia, a pair of bipolar catheter electrodes was introduced to the epidural space: one at the level of the cervical enlargement and the other at the lumbosacral enlargement. The conducting ESCP was produced by electrical stimulation through the upper electrode and recorded through the lower electrode, and vice versa. SDH Study: Subjects were 6 patients who underwent replacement surgery of an aortic aneurysm with deep hypothermia anesthesia. The peak latency of the ESCP was gradually prolonged and the duration was widened with cooling via extracorporeal circulation. The amplitude of ESCP showed a biphasic change over the course of cooling with a turning point of around 30°C in esophageal temperature. The ESCP was well observed until blood temperatures as low as near 10°C. The result shows that ESCP is available as an intra-operative monitoring parameter of the spinal function even under SDH. SAB Study: Subjects were 7 patients, 6 of whom had SAB and the remaining 1 intravenous application of a local anesthetic. The conducting ESCP was markedly depressed or disappeared completely even after SAB with clinical doses of various local anesthetics, while it was hardly affected by the intravenous application. The result implies that SAB causes, at least partially, the conduction block within the spinal cord.
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  • HIROYUKI MIHASHI, AKIHIKO KAWAHARA, MASAYOSHI KAGE, MASAMICHI KOJIRO, ...
    2006 Volume 53 Issue 1+2 Pages 23-27
    Published: July 15, 2006
    Released on J-STAGE: October 11, 2006
    JOURNAL FREE ACCESS
    We investigated 115 patients with salivary gland epithelial tumors who had undergone preoperative fine needle aspiration cytology (FNAC) of salivary glands and had been diagnosed by postoperative histopathological examination. We compared the findings of preoperative FNAC with their histopathological types in salivary gland tumors, and discuss the results and problems. The diagnostic accuracy, sensitivity, and specificity of preoperative FNAC of salivary glands were 98.2%, 88.2%, and 100%, respectively. The percentage of inadequate specimens was 6.1%. The rates of agreement in the diagnosis of pleomorphic adenoma, Warthin tumor, and basal cell adenoma were 96%, 92.9%, and 55.5%, respectively. The rate of agreement of histopathological types in the malignant tumors was 30%. We realized again not only that the diagnostic accuracy of preoperative FNAC for salivary gland tumors was high, but also that it was a safe, easy-to-perform, clinically very useful diagnostic procedure. However, this study exposed several problems which are the inadequate sampling rate and the difficulty in diagnosing malignant tumors. We have been making efforts to take appropriate specimens by writing comments on the cytological report indicating a re-examination, or by the presence of the clinical laboratory technician at the FNAC procedure. We consider it necessary to adequately re-aspirate the solid portion after cyst fluid aspiration, or to re-perform FNAC at a later date, and to improve the diagnostic accuracy by further experience with more patients.
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  • RYOICHI MITSUZONO, MAKOTO UBE
    2006 Volume 53 Issue 1+2 Pages 29-35
    Published: July 15, 2006
    Released on J-STAGE: October 11, 2006
    JOURNAL FREE ACCESS
    The purpose of this study was to investigate the cross-sectional and longitudinal effects of endurance training on the relationships of body composition, blood lipid profiles and sex hormones in adolescent female distance-runners. We cross-sectionally compared body composition, blood lipid profiles and blood sex hormones of non-athletes (n=7) and distance-runners (n=8), with the similar lower level of BMI (17.1 kg/m² vs. 18.7 kg/m², respectively). After the cross sectional comparison on the influence of endurance training, body composition, blood lipid profiles and blood sex hormones were examined at pre- and post-one year endurance training in the distance-runners (n=6) to determine longitudinal effects. %Fat in distance-runners revealed a tendency to be lower than that in non-athletes (23.8±3.5 vs 27.3±2.5%). Both groups showed good blood lipid profiles, such as high levels of high density lipoprotein-cholesterol (HDL-c), HDL-2c, and apolipoprotein A-I (ApoA-I). However, the estrogen (E2) level of distance-runners was less than one third of that in non-athletes (30.5±11.3 vs 112.9±66.2 pg/ml, p<0.01). In addition, the blood E2 levels (pg/ml) were significantly associated with the internal fat mass (IF, kg) in all subjects (r=–0.613, p<0.05, n=15). On the other hand, the overall body composition and good blood lipid profiles in the longitudinal comparison were maintained to a constant level for one year endurance training, except for significant elevations in the two enzyme activities and E2 level (LPL activity: from 145.3±40.8 to 362.2±65.8 ng/ml, HTGL activity: from 0.054±0.020 to 0.173±0.080μmole/ml/min, E2: from 30.7±13.2 to 65.6±24.2 pg/ml, p<0.05). These results suggest that the lipid profiles such as HDL-c and Apo A-I in adolescent female distance-runners could be rather affected by endurance training, despite the low level of E2 for a long term.
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Case Report
  • SHUNJI ARIKAWA, MASAFUMI UCHIDA, MASAHARU SHINAGAWA, TATSUYUKI TOHNAN, ...
    2006 Volume 53 Issue 1+2 Pages 37-40
    Published: July 15, 2006
    Released on J-STAGE: October 11, 2006
    JOURNAL FREE ACCESS
    A case of uterine lipoleiomyoma in a 72-year-old woman is presented. Although a series of imaging studies suggested a lipomatous tumor, diagnosis was difficult because the tumor appeared as a pedunculated mass extending from the uterine body. To distinguish the tumor from an ovarian lipomatous tumor, the “beak sign” in a magnetic resonance imaging study was diagnostic in this case. The purpose of this paper is to review lipomatous masses of the female pelvis, to discuss the differential diagnosis of the unusual imaging features, and to discuss imaging techniques to optimize pelvic mass characterization.
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  • TAKUMI KAWAGUCHI, EITARO TANIGUCHI, MINORU ITOU, JYUNJI AKIYOSHI, SATO ...
    2006 Volume 53 Issue 1+2 Pages 41-46
    Published: July 15, 2006
    Released on J-STAGE: October 11, 2006
    JOURNAL FREE ACCESS
    Loss of appetite is frequently seen and is a main factor affecting quality of life (QOL) in patients with advanced cancer. The etiology for loss of appetite in patients with cancer is multifactorial. The sensory properties of food are factors regulating appetite. Changes in taste, smell and texture of foods influence food intake. The appearance of the food is also a notable factor in sensory-specific satiety. We described a 46-year-old Japanese woman with multiple metastatic liver tumors. Although there was no obvious factor for loss of appetite, she suffered from a loss of appetite and subsequent malnutrition. In order to improve the appearance of food, we reduced the diet to 1000 kcal/day from 1500 kcal/day. On the new diet, the patient’s appetite significantly increased and patient’s nutritional status was improved. Eating whole diet was an important achievement and increased in mental aspects of QOL. Arrangement for the appearance of food may be a simple and nontoxic therapeutic strategy for patients with cancer suffering a loss of appetite.
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